Custom Peptides
Cayman Chemical O6-BenzylgunIn 10mg
A guanine analog with antineoplastic activity; irreversibly inactivates AGT, with 40% reduction in alkyltransferase activity achieved at 0.06 µM with recombinant human AGT; effective in vivo as well as in vitro
Cayman Chemical LAPtrIfluoroacetate salt 10mg
An antiviral peptide; inhibits the HCV 5’-UTR-PTB and HCV 5’-UTR-PCBP2 interaction; inhibits HCV IRES-mediated translation in a reporter assay using Huh7 cells at 60 µM
Cayman Chemical VnP16trIfluoroACTAte salt 10mg
A synthetic peptide fragment of vitronectin; induces attachment and cell spreading of isolated human osteogenic cells when applied to cell plates at 9.1 UG/cm2; induces osteogenesis of human skin-derived mesenchymal precursors and MC3T3-E1 mouse calvarial osteoblast precursors; decreases IL-1α-induced bone loss and decreases the number of calvarial osteoclasts in mice; increases bone mineral density and decreases trabecular bone loss in a mouse model of ovariectomy-induced bone loss
Cayman Chemical PB22 NpentnoIc ACD metabo 10mg
A potential metabolite of PB-22; intended for forensic and research purposes
Cayman Chemical FexapotIdetrIfluoroacetAT 10mg
A peptide with anticancer activity; induces apoptosis in LNCaP prostate cancer cells at 2.5 mg/ml; reduces the numbers of prostate glandular epithelial cells without affecting other cell types and decreases prostate volume in rats when administered intraprostatically at 0.6 mg/animal per week
Cayman Chemical D609potasIum salt 10mg
A competitive inhibitor of PC-PLC (Ki = 6.4 µM); has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D; reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations when used at concentrations of 100 and 200 mg/ml, respectively; has antioxidant, antiviral, and anti-tumor activities; inhibits LPS-stimulated NOS expression in phagocytes (IC50 = 20 UG/ml) and IL-1β-induced VCAM-1 expression in endothelial cells
Cayman Chemical 2C-ThydrochlorIde 10mg
A member of a family of 2,5-dimethoxy phenethylamines, substituted on the four position of the aromatic ring with an methylthio group; intended for forensic and research purposes
Cayman Chemical UAMC-3203hydrochlorIde 10mg
A ferroptosis inhibitor (IC50 = 10 nM for erastin-induced ferroptosis in IMR-32 cells); decreases iron-induced plasma LDH levels in a mouse model of acute iron poisoning at 20 µmol/kg; not toxic to mice at 20 µmol/kg for four weeks
Cayman Chemical Cholesterol-d6 10mg
An internal standard for the quantification of cholesterol by GC- or LC-MS
Cayman Chemical RosuvastatIncalcIum salt 10mg
An HMG-CoA reductase inhibitor (IC50 = 5 nM); inhibits cholesterol synthesis in isolated rat hepatocytes (IC50 = 0.16 nM); reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet at 10 mg/kg; decreases the area of aortic atherosclerotic lesions in the same model
Cayman Chemical PropIophenon 10mg
An analytical reference standard categorized as a precursor in the synthesis of cathinones; intended for research and forensic applications
Cayman Chemical TRx0237mesylate 10mg
An inhibitor of tau aggregation; inhibits tau-tau binding (IC50 = 238 µM) and tau aggregation in 3T6H cells expressing human tau (EC50 = 0.19 µM); increases hippocampal ACh and synaptophysin levels, as well as increases mitochondrial complex IV activity, decreases tau pathology, and reverses deficits in spatial learning in the L1 transgenic mouse model of Alzheimer’s disease
Cayman Chemical Indoxyl SulfATd5potasIum 10mg
An internal standard for the quantification of indoxyl sulfate by GC- or LC-MS
Cayman Chemical HomobrasInolIde 10mg
A brassinosteroid; field application increases the number of fruits per plant, fruit length, and fruit breadth in tomato plants at 0.12 g/ha