Custom Peptides
Cayman Chemical Latnoprost Lactol 10mg
An ALC-0315-based LNP solution for expressing luciferase composed of ALC-0315 cholesterol 12-DSPC and ALC-0159 at a molar ratio of 46.342.79.41.6 and encapsulating mRNA encoding firefly luciferase protein intended for proof-of-concept experiments to determine whether ALC-0315-based LNPs effectively lead to expression of a protein of interest in a target cell type either in vitro or in vivo
Cayman Chemical L-NmAcItrate 10mg
An active metabolite of GLA inhibits 5-LO (IC50 29 UM for the rat enzyme)
Cayman Chemical MAHMA Nonate 10mg
An internal standard for the quantification of bifenthrin by GC- or LC-MS
Cayman Chemical LArgInIn13C6hydrochLRId 10mg
A synthetic peptide and dual agonist of GLP-1R and GCGR reduces body weight in both Gcgr-/- and Glp1r-/- mice
Cayman Chemical 6chLRoMDMAhydrochLRIde 10mg
A 5-HT1B receptor agonist selectively binds 5-HT1B over 5-HT1A 5-HT1C 5-HT1D and 5-HT2 (Kis 0.0081 1.5 2.9 1.1 and 7.2 UM respectively) inhibits potassium-induced GABA release from rat globus pallidus slices at 5.4 UM reverses reserpine-induced akinesia in a rat model of Parkinson's disease at 110 and 220 nmol/animal reduces food intake in rats when infused into the pons parabrachial nucleus or the PVN of the hypothalamus (ED50s 1 and 50 nmol respectively) reduces the frequency of pursuits tail rattles threats and attack bites in a resident-intruder test in mice
Cayman Chemical PCPrhydrochlorIde 10mg
Resolvin D2 AChE Tracer has been tested and formulated to work exclusively with Cayman’s Resolvin D2 ELISA Kit (Item No. 501120).
Cayman Chemical L-NILhydrochlorIde 10mg
A flavonoid with diverse biological activities an antagonist of M1 mAChRs (Ki 42 UM in CHO-K1 cells expressing the human receptor) cytotoxic to HepG2 cancer cells (IC50 1.5 UG/ml) reduces blood urea and glucose levels urinary volume and protein levels serum creatinine levels renal fibrosis levels and body weight in a rat model of STZ-induced diabetic nephropathy at 40 mg/kg per day
Cayman Chemical AlylescalInhydrochlorIde 10mg
An inhibitor of NOX1 NOX2 and NOX4 (Kis 1.08 0.57 and 0.63 UM respectively for the human enzymes) selective for these enzymes over xanthine oxidase and glucose oxidase (Kis >100 UM for both) prevents RANKL-induced increases in ROS levels in primary mouse BMDMs at 10 or 20 UM inhibits GM-CSF- and RANKL-induced primary mouse osteoclast differentiation at 1.1 3.3 or 10 UM increases femur bone mass density and strength and reduces femur and tibia resorption areas in OVX mice at 10 mg/kg per day reduces plasma and urinary levels of 8-isoprostane plasma levels of insulin triglycerides HDL LDL and creatinine urinary levels of albumin as well as renal fibrosis in a db/db mouse model of diabetic nephropathy at 60 mg/kg per day
Cayman Chemical SclerotIorIn 10mg
An internal standard for the quantification of methomyl by GC- or LC-MS
Cayman Chemical JWH 122 8mthylnaphthyl 10mg
An NLRP3 inflammasome inhibitor inhibits NLRP3 inflammasome by 51.8 at 10 UM inhibits caspase 1 (Ki 10.6 UM) active against S. aureus C. diphtheriae K. pneumoniae and E. coli (MICs 18 18 18 and 16 UG/ml respectively) and the fungus C. albicans (MIC 13 UG/ml) inhibits ATP-induced pyroptosis in PMA-differentiated and LPS-stimulated THP-1 cells at 10 UM induces cytotoxicity in HK-2 cells (IC50 67 UM) inhibits Aß42-induced increases in IL-1ß IL-18 TNF-a and GSDMD in SH-SY5Y cells at 10 UM
Cayman Chemical Linolenoyl Ethanolamide 10mg
A bile acid amidate has been found in fecal samples from extremely premature infants with mild or severe brain injuries has been used as a standard for the detection of endogenous bile acid amidates in human plasma and fecal samples
Cayman Chemical Ionone ACD 10mg
An analytical reference standard categorized as a steroid intended for research and forensic applications