Custom Peptides
BANGS LABORATORIES INC Bangs Quantum™ Alexa Fluor 647 MESF Kit, Fluorescence Standardization, 100 Tests
The Bangs Laboratories Quantum™ Alexa Fluor 647 MESF 5mL kit is essential for quantitative fluorescence cytometry. It standardizes fluorescence intensity units through a calibration curve correlating instrument values with MESF units. Its key benefits include accurate cellular expression analysis and evaluation of instrument performance, with microspheres labeled for environmental responsiveness.
Cayman Chemical A20FMDV2trIfluoROCTAte sa 10mg
An EIF2AK3 activator increases phosphorylation of eIF2a at serine 51 in HT-29 and MCF-7 cells at 10 UM an effect not seen in cells transfected with EIF2AK3 siRNA reduces phosphorylation of Rb in HT-29 cells (EC50 5.1 UM) rapidly reduces the level of cyclin D1 in HT-29 cells at 10 UM inhibits the growth of HT-29 colon carcinoma cells (GI50 2.1 UM)
Cayman Chemical GluR2831-842humnmouse 10mg
An alkaloid with anticancer and antimalarial activities selectively inhibits the growth of OVCAR-8 A2780 IGROV-1 and OVCAR-4 ovarian cancer cells (IC50s 10 7.6 14 and 7.2 UM respectively) over non-cancerous ovarian surface epithelial cells (IC50 35 UM) ) reduces parasitemia and increases survival in a mouse model of infection with a chloroquine-resistant strain of P. berghei at 25 and 50 mg/kg
Cayman Chemical TyphnosIde 10mg
A steroidal saponin with diverse biological activities inhibits UGT1A4 (IC50 10.5 UM) cytotoxic to K562 cells (IC50 ~7.5 UM) improves neurological function and decreases neuronal damage in a rat model of spinal cord injury at 100 mg/kg decreases serum levels of glucose insulin and triglycerides in diabetic db/db mice at 50 mg/kg reduces serum MDA levels and stomach MPO activity in a mouse model of ethanol-induced gastric ulcers
Cayman Chemical S-Acenocoumarol 10mg
An internal standard for the quantification of hydrochlorothiazide by GC- or LC-MS
Cayman Chemical SynthetIc FumagIlol 10mg
An LMP7 inhibitor (IC50 4.1 nM) selective over the 20S proteasomal catalytic subunits B1 -B2 and -B5 (IC50s 10000 2519 and 10000 nM respectively) as well as LMP2 and PSMB10 (IC50s 10000 nM for both) increases ubiquitinated protein levels (EC50 1980 nM) and induces apoptosis in MM.1S cells (EC50 420 nM) reduces tumor volume in U266B1 OPM-2 and RPMI-8226 mouse xenograft models of multiple myeloma at 10 mg/kg per day
Cayman Chemical NMethylNnItrosopIperazIn 10mg
A synthetic intermediate has been used in the synthesis of antibacterial or kinase-inhibiting purines as well as anticancer agents increases survival time in combination with azaserine in an S180 mouse model of sarcoma at 20 mg/kg per day
Cayman Chemical Buca javnca L M. Bucn D 10mg
A PDE3 inhibitor (IC50 0.4 nM) selective for PDE3 over PDE4 (IC50 1479 nM) reduces the phytohemagglutinin-induced proliferation of isolated human monocytes inhibits LPS-induced increases of TNF-a protein levels in isolated human monocytes (IC50 520 nM) increases cAMP levels in isolated human neutrophils at 10 UM inhibits electric field stimulation-induced contractile responses in isolated guinea pig trachea in a concentration-dependent manner intranasal administration inhibits histamine-induced bronchoconstriction and tracheal edema in guinea pigs at 25 w/w
Cayman Chemical MyrIstoylCoenzyme AsodIum 10mg
A thioredoxin inhibitor inhibits Trx activity in ES-2 cells at 20 UM cytotoxic to ES-2 cells (IC50 1.6 UM) induces ferroptosis in ES-2 cells at 5 UM an effect that can be blocked by DFO Trolox or ferrostatin-1 decreases tumor volume in a 4T1 murine mammary carcinoma model using immunocompetent but not immunodeficient mice at 50 mg/kg twice per week
Cayman Chemical CobImetInIb 10mg
A membrane-permeable cationic dye that is a substrate for P-gp and is rapidly exported from cells with functional P-gp also accumulates within mitochondria and can inhibit oxidative phosphorylation ex/em 507/529 nm
Cayman Chemical CyclosporIn B 10mg
A potent selective inhibitor of PDE7 inhibiting human recombinant PDE7A1 with a Ki value of 180 nM enhances the inhibitory effects of the PDE4 blocker rolipram on monocytes lung macrophgaes and CD8 T-lymphocytes promotes apoptosis in chronic lymphocytic leukemia cells overexpressing PDE7B
Cayman Chemical AmInoethylsPropIonIc AcId 10mg
A flavanone glucoside active against H pylori at 0 5 mM scavenges DPPH radicals (IC50 2 04 mM) and inhibits the activity of intestinal maltase and HMG-CoA reductase (Kis 1800 and 9 8 UM respectively for the human enzymes) in cell-free assays prevents decreases in bone mineral density in the femur of ovariectomized rats at 2 5 and 5 g/kg diet
Cayman Chemical Benoxaprofen 10mg
Immunogen Peptide corresponding to the internal region of human Ki-67 Host Rabbit Species Reactivity ( ) Human Cross Reactivity ( ) Ki-67 Applications IHC WB
Cayman Chemical Latnoprost Lacton DIol 10mg
An alkaloid with enzyme inhibitory activity an inhibitor of AChE BChE and prolyl endopeptidase (IC50s 281 911 and 907 UM respectively)