Custom Peptides
Genscript Corporation OVA Peptide (257-264)
This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
New England Biolabs, Inc. Trypsin-digested BSA MS Standard (CAM-modified) – 500 pmol
This standard is a complex mixture of peptides produced by the tryptic digest of reduced and alkylated Bovine Serum Albumin (BSA). This peptide mixture can be used to test a Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer (TOF, Q-TOF or Ion Trap).
Cayman Chemical AmInoacetonhydrochlorIde 10mg
A natural plant alkaloid commonly used to alleviate inflammation associated with rheumatoid arthritis activates histamine release reduces joint stiffness and pain and alters cytokine generation impairs signaling through NF-KB resulting in immunosuppression as well as reduced inflammation and pain
Cayman Chemical 4NItrophenylNacetylaDga 10mg
A B1-selective adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity often used to examine the activity of the drug-transporting MDR1 gene product P-glycoprotein
Cayman Chemical PalonsetronhydrochlorIde 10mg
An antimalarial agent active against six P. falciparum drug-sensitive or -resistant strains (IC50s 1.53-3.94 nM) reduces parasitemia in P. chabaudi-infected mice at 3 6 and 8 mg/kg in combination with artesunate inhibits SARS-CoV-2 replication in infected A459-ACE2 cells (IC50 198 nM) cytotoxic against a panel of human cancer cells lines (CC50s 1.6-4.9 UM)
Cayman Chemical PhosphatIdylethnolamInbov 10mg
An antagonist of NMDA receptors with high affinity for the glycine binding site (Ki 140 nM) that is functional both in vitro and in vivo also an agonist of GPR17 (EC50 values range from 7 nM to 6 UM depending on the assay)
Cayman Chemical ResmInostathydrochlorIde 10mg
ABAR antagonist (IC50s 8.9 and 5.2 M for B1- and B2-ARs respectively) and a class III antiarrhythmic agent decreases IK in guinea pig ventricular cells and prolongs action potential duration in electrically stimulated isolated guinea pig papillary muscles at 100 M decreases heart rate and increases blood pressure and the cardiac FRP in a canine model of PES-induced ventricular tachycardia
Cayman Chemical 17phenl trInor ProstglndI 10mg
A 5-HT1B and 5-HT1D receptor agonist (Kis 4.3 and 10.1 nM respectively) selective for 5-HT1B and 5-HT1D receptors over 5-HT1A receptors (Ki 140 nM) induces vasoconstriction in isolated human middle meningeal arteries (EC50 90 nM) reduces pain behaviors and photophobia in a Cacna1a mutant transgenic mouse model of migraine at 50 and 75 mg/kg
Cayman Chemical AcYVADpNAtrIfluoroACTAte 10mg
5-trans PGF2a is the more thermodynamically stable C-5 olefin isomer of PGF2a and is a common impurity in commercial lots of PGF2a. 5-trans PGF2a administered intravenously to anesthetized rabbits caused a substantial (ten-fold) increase in respiratory rate but this attribute was common to a number of F-series compounds and analogs.{2224}
Cayman Chemical E-8-Methyl-6-nonoIc AcId 10mg
A potent inhibitor of MEK5 (IC50 4.3 nM) and moderate inhibitor of ERK5 and TGFBR1 (IC50s 810 and 1800 nM respectively)
Cayman Chemical 7fluoro TryptamInhydrochl 10mg
An alkaloid reduces the number of dsDNA breaks induced by nitrosamine in a comet assay using HepaRG cells at 5 and 50 UM
Cayman Chemical 20-ethyl ProstaglndIn F2a 10mg
A BH3 mimetic that selectively inhibits Bcl-2 (Ki 3-fold less avidly to the related family proteins Bcl-xL and Bcl-W (Kis 48 and 245 nM respectively) inhibits the growth of Bcl-2-dependent cell lines and in vivo tumor xenografts and demonstrates antileukemic activity in patients with refractory chronic lymphocytic leukemia