Custom Peptides
Cayman Chemical L-3-n-ButylphthalIde 10mg
A phthalide with antiplatelet and neuroprotective activities; inhibits ADP-, collagen-, and arachidonic acid-induced platelet aggregation ex vivo at 3-100 mg/kg; inhibits thrombus formation in a collagen and epinephrine-induced rat model of experimental thrombosis; reduces amyloid-β-induced decreases in GPX activity and decreases MDA levels in the cortex and hippocampus and improves spatial learning and memory in the Morris water maze in a rat model of Alzheimer’s disease induced by i.c.v. infusion of amyloid-β (1-40)
Cayman Chemical 3hydroxy DecNIc ACD mthy 10mg
A hydroxy fatty acid methyl ester; has been found in PHA polymers produced by P. putida and D. tsuruhatensis; has antibacterial activity against S. faecalis AD-4
Cayman Chemical 1 2DIlauroylracglycerol 10mg
A diacylglycerol; has been used as an internal standard for the quantification of diacylglycerols in rat desheathed sciatic nerves; has been used in monomolecular films as substrates to measure the effects of surface pressure and pancreatic procolipase and colipase on the activity of porcine pancreatic lipase
Cayman Chemical 10deACtyl7xylosyl PaclIta 10mg
A microtubule disruptor; induces the disassembly of pig brain and Physarum microtubules in cell-free assays (IC50s = 0.3 and 0.5 µM, respectively); inhibits proliferation of (IC50 = 5 µM), as well as induces cell cycle arrest at the G2/M phase and apoptosis in, PC3 cells
Cayman Chemical Broprmn 10mg
An immunomodulator with diverse biological activities; a TLR7 agonist that inhibits RANKL-induced osteoclast differentiation of murine BMDMs; dietary administration prevents development of TCCs in a mouse model of carcinogen-induced bladder carcinoma at 200 mg/kg twice per week; reduces pulmonary collagen accumulation and BALF monocyte and eosinophil infiltration in a hamster model of bleomycin-induced lung fibrosis at 100 mg/kg; delays disease onset and progression and increases plasma IFN levels in a mouse model of EAE
Bachem H-Asp-Asp-OH
H-Asp-Asp-OH, 58471-53-7, C8H12N2O7, Mr 248.19, 1g. Dipeptides as aspartylaspartate and glutamylglutamate can be utilized as growth substrates for the oral bacteria Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Fusobacterium nucleatum.
Cayman Chemical 8-DesoxygartnIn 10mg
A xanthone with anti-inflammatory and enzyme inhibitory activities; inhibits NF-κB p65 binding to DNA in a cell-free assay in an enzyme assay (IC50 = 11.3 µM); inhibits BChE and AChE (IC50s = 2.46 and 7.75 UG/ml)
Cayman Chemical JWH 203 4CLOrophenl IsomR 10mg
An analytical reference standard categorized as a synthetic cannabinoid; reduces spontaneous locomotor activity, but does not induce antinociception or a decrease in body temperature, in mice; intended for research and forensic applications
Cayman Chemical 4ethylN NDImethylcathInon 10mg
A potential stimulatory designer drug of the amphetamine and cathinone chemical classes; intended for forensic purposes
Cayman Chemical RucaparIbphosphate 10mg
A PARP1 inhibitor; reduces PARP1 activity in D283 Med cancer cells by 91.7% at 1 µM; selectively inhibits the proliferation of MDA-MB-436 cancer cells expressing mutant BRCA1 (IC50s = 1.3 µM) over MCF-7 cancer cells expressing wild-type BRCA1 and BRCA2 (IC50s = 20.2 µM); potentiates temozolomide-induced growth inhibition in D283 Med and D384 Med cells at 0.4 µM; potentiates temozolomide-induced delays in tumor growth in D283 Med and D384 Med mouse xenograft models at 1 mg/kg per day
Cayman Chemical LuteolosIde 10mg
A flavanoid with diverse biological activities; reduces LDH and caspase-3 activities and production of ROS and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury; blocks 3C protease activity (IC50 = 0.36 mM); reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM); inhibits the growth of HCC cells in vitro and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model at 2 mg/kg; reduces acanthosis and expression of epidermal differentiation markers in a mouse model of imiquimod-induced psoriasis
Cayman Chemical aPyroldInopentIophenon me 10mg
An analog of α-PVP in which the keto group is reduced; intended for forensic and research purposes
Cayman Chemical AvIbactamsodIum salt 10mg
A β-lactamase inhibitor (IC50s = 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively); restores antimicrobial activity of ceftazidime, ceftriaxone, imipenem and piperacillin in vitro (MIC90 reduction 4-1024-fold across 190 E. coli and K. pneumoniae clinical isolates)
Cayman Chemical S-PhenylmercapturIc AcId 10mg
A metabolite of benzene; used as a biomarker for benzene exposure; urinary concentrations up to 543 UG/g creatinine have been detected