Custom Peptides
Cayman Chemical 1-DeoxymnojIrImycInhydroc 10mg
A specific inhibitor of class I α-1,2-mannosidase (IC50 = 20 mM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi; inhibiting α-1,2-mannosidase with 1-Deoxymannojirimycin generates N-linked oligosaccharides with high mannose content, preventing proteasomal degradation of misfolded proteins
Cayman Chemical MaleIMDoACtIc ACD Nhydrox 10mg
A crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 Å spacer arm; used for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates
Cayman Chemical NundecnoylLHomoserIn lac 10mg
A bacterial quorum-sensing signaling molecule; induces GFP production in E. coli expressing the V. fischeri LuxR-PluxI quorum-sensing operon from 100-1,000 nM; inhibits concanavalin A-induced proliferation of isolated mouse splenocytes (IC50 = 90 µM)
Cayman Chemical 4acetoxy DEThydrochLRIde 10mg
An analytical reference standard categorized as a tryptamine; induces the HTR in mice; intended for research and forensic applications
Cayman Chemical 17trIfluoromthylphnyl13 1 10mg
A number of 17-phenyl trinor PGF2α derivatives have been approved for the treatment of glaucoma.{8941,9341,8839} Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.{9736} 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2α would act very much like the free acid of latanoprost.
Cayman Chemical Lacto-N-tetraose 10mg
An oligosaccharide; promotes the growth of the bacterium B. longum and B. breve; levels are increased in breast milk from mothers of rotavirus-positive neonates with gastrointestinal symptoms and are positively correlated with levels of Enterobacter and Klebsiella in maternal milk and infant stool
Cayman Chemical -Cloprostenol 10mg
A synthetic analog of PGF2α; an FP receptor agonist and a potent luteolytic agent in rats and hamsters; the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity
Cayman Chemical IQ-1Sfree acId 10mg
An inhibitor of NF-κB/AP-1 (IC50 = 2.3 µM in a reporter assay); inhibits the production of TNF-α and IL-6 production in human Mono-Mac-6 cells (IC50s = 1.3 and 3.8 µM, respectively) and isolated human PBMCs (IC50s = 2.6 and 5.6 µM, respectively), as well as NO production in murine J774-A.1 macrophages (IC50 = 3.1 µM); binds to JNKs (Kd = 0.24, 0.36, and 0.1 for JNK1-3), as well as CK1δ, PI3Kγ, and MKNK2 (Kds = 0.38, 0.47, and 0.92 µM, respectively)
Cayman Chemical HederasponIn B 10mg
A triterpene saponin with antiviral and antioxidant activities; inhibits the cytopathic effect induced by the EV71 genotypes C3 and C4a (EC50s = 24.77 and 41.77 UG/ml, respectively), as well as reduces expression VP2, in Vero cells; inhibits superoxide generation in human neutrophils at 100, 150, and 200 UG/ml
Cayman Chemical PalIfosfamIde 10mg
An active metabolite of ifosfamide; formed through hydroxylation of ifosfamide by various hepatic CYP isoforms; cytotoxic to L1210 and CCRF-CEM cancer cells at 100 µM; reduces tumor growth in Lewis lung carcinoma and L1210 leukemia mouse models, as well as a rat Yoshida ascitic sarcoma model at 100 mg/kg per da
Cayman Chemical BofutrelvIr 10mg
An inhibitor of Mpro (IC50 = 0.053 µM in a TR-FRET assay); reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50 = 0.53 µM); reduces viral RNA copy numbers in the same model from 1.85-50 µM
Cayman Chemical R-OfloxacIn 10mg
A fluoroquinolone antibiotic; the (R) isomer of ofloxacin and levofloxacin; active against certain Gram-positive and Gram-negative bacteria, including E. coli, P. aeruginosa strains 32104 and 32122, S. aureus strains 209P and Smith, and S. epidermis strain 56556 (MICs = 0.78, 12.5, 6.25, 25, 12.5, and 25 UG/ml, respectively) but not S. epidermis strain 56500, S. pyogenes, or S. faecalis (MICs = >100 UG/ml for all); inhibits E. coli DNA gyrase with an IC50 value of 75 UG/ml, which is approximately 30- and 50-fold lower than inhibition by ofloxacin and levofloxacin, respectively
Cayman Chemical Glycoursodeoxycholc ACDd4 10mg
An internal standard for the quantification of glycoursodeoxycholic acid by GC- or LC-MS
Cayman Chemical MacrnthoIdIn B 10mg
A triterpenoid saponin with anticancer activity; increases the production of ROS and induces apoptosis in HCT116 cells from 20-400 µM