Drug Discovery Research Screening Libraries
Drug Discovery Research Screening Libraries
Enzo Life Sciences SCREEN-WELL Natural Product library (1 Library)
Natural products are an unsurpassed source of chemical diversity and an ideal starting point for any screening program for pharmacologically active small molecules. Historically, natural products have been the most successful source of new drugs. The SCREEN-WELL Natural Product library offers over 500 isolated natural compounds of known structure and includes many compounds from ethnopharmacology. Compounds are provided in solution in DMSO. Individual compounds or subsets can be resupplied in gram quantities. Contents: 502 compounds including compounds from the following classes of products: Terpenoids, Peptolides, Flavones, Coumarins, Alkaloids, Macrolides, Isoflavones, Synthetic derivates and many more. Application: HTS. Use/Stability: Stable for at least one year from the date of receipt when stored at -80°C. Long Term Storage: -80°C
Apexbio Technology LLC DiscoveryProbe™ Ion Channel Compound Library Plus, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap, 250uL/well(10 mM solution),96 Well Racks With Screw Cap
DiscoveryProbe™ Ion Channel Compound Library Plus is a unique collection of 350 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation. Other sizes are also available. Please inqury us for quote.
Selleck Chemical LLC Anti-cancer Compound Library 100uL/well
A unique collection of 3547 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences SCREEN-WELL GABAergic ligand library (500 µl/well)
The GABAergic Ligands library contains 56 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The GABAergics Ligands plate is 1 plate of the larger Neurotransmitter Library (BML-2810) which contains over 650 CNS receptor ligands. Long Term Storage: -80°C. Applications: HTS .
AdipoGen Lac-Phe Acetate
Chemical. CAS 183241-73-8. Formula C12H15NO4 . C2H3O2. MW 237.3 . 59.0. Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise in mammals and acts to reduce food intake and potentially decrease overall body weight and fat mass. In diet-induced obese mice, pharmacological administration of Lac-Phe led to decreased food intake, adiposity and body weight, as well as improved glucose homeostasis, while movement and energy expenditure were not affected. The biosynthesis of Lac-Phe from lactate and phenylalanine occurs in CNDP2 cells, including macrophages, monocytes and other immune and epithelial cells.
Apexbio Technology LLC DiscoveryProbe™ Autophagy Compound Library Plus, 100uL/well(10 mM solution),96 Well Racks With Screw Cap
DiscoveryProbe™ Autophagy Compound Library Plus is a unique collection of 837 autophagy-related compounds for autophagy research. Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation. Other sizes are also available. Please inqury us for quote.
eMolecules AstaTech / 3-CHLOROPHENYL ISOTHIOCYANATE / 1g / 374899895 / H11337 / 95.000 / 2392-68-9 / MFCD00004805 / 169.630 / C7H4ClNS
AstaTech / 3-CHLOROPHENYL ISOTHIOCYANATE / 1g / 374899895 / H11337 / 95.000 / 2392-68-9 / MFCD00004805 / 169.630 / C7H4ClNS
eMolecules Medchem Express / N-Desmethylclozapine-d8 (hydrochloride) / 5mg / 761506678 / HY-G0021S1 / / 2705402-91-9 / [null] / 357.310 / C17H18Cl2N4
Medchem Express / N-Desmethylclozapine-d8 (hydrochloride) / 5mg / 761506678 / HY-G0021S1 / / 2705402-91-9 / [null] / 357.310 / C17H18Cl2N4
eMolecules Medchem Express / Proguanil-d6 (hydrochloride) / 5mg / 784544339 / HY-B0806AS1 / / / [null] / 296.230 / C11H17Cl2N5
Medchem Express / Proguanil-d6 (hydrochloride) / 5mg / 784544339 / HY-B0806AS1 / / / [null] / 296.230 / C11H17Cl2N5
AdipoGen Zilpaterol hydrochloride
Chemical. CAS 119520-06-8. Formula C14H19N3O2 . HCl. MW 297.78. Synthetic. Synthetic beta2-adrenoreceptor agonist that binds with the muscle beta-adrenoreceptors, leading to the activation of protein kinase A, an enzyme responsible for changes in protein synthesis and degradation, in particular in skeletal muscles. Due to its partial activity towards beta1-adrenoreceptors, has also the potential to affect cardiac muscle. In consequence, application of zilpaterol leads to preferential induction of fast glycolytic fibre types over slow oxidative fibre types resulting in enhanced growth efficiency and carcass leanness. Used as a veterinary drug in cattle to enhance growth performance in several countries.
AdipoGen DTagatose
Chemical. CAS 87-81-0. Formula C6H12O6. Molecular Weight 180.16. D---Tagatose, is a ketohexose acting as a low-calorie functional sweetener. It is a sugar substitute found in small quantities in nature and produced using a biotransformation method with L-arabinose isomerase as the biocatalyst and D-galactose as the substrate. Tagatose can be used as a preservative in cosmetic, detergent and pharmaceutical formulations. Tagatose is also used in diet soft drinks, chewing gum, frozen yogurt and non-fat ice cream. Potential sugar substitute rarely found in nature. Since it is metabolized differently from sucrose, tagatose has a minimal effect on blood glucose and insulin levels. Tagatose is also approved as a tooth-friendly ingredient for dental products. Tagatose has very similar sweetness to sugar while its glycemic index is very low. Tagatose reduces blood glucose level in the liver by promoting glucokinase activity which promotes transfer of glucose to glycogen.
Kyfora Bio DOTAP CHLORIDE 25MG
DOTAP Chloride (N-[1-(2 3-Dioleoyloxy)propyl]-N N N-trimethylammonium chloride) is a widely used cationic liposome-forming compound forin vitroandin vivotransfection of DNA RNA and other negatively charged molecules. DOTAP encapsulates nucleic acids to spontaneously form stable complexes via electrostatic interactions facilitates cell attachment internalization by endocytosis and endosomal escape by proton sponge. It has been used in formulations for Lipid Nanoparticles (LNPs) and Nanostructured Lipid carriers (NLCs) in the development of mRNA vaccines including COVID-19 vaccines and drug delivery systems. APPLICATIONS Transfection of DNA RNA and oligonucleotides Lipid Nanoparticles (LNPs) Nanostructured Lipid Carriers (NLCs) mRNA vaccine development drug delivery system development.
AdipoGen Xylitol
Chemical. CAS 87-99-0. Formula C5H12O5. MW 152.15. Synthetic. Sugar alcohol used as a sweetener. Unlike other natural or synthetic sweeteners, xylitol is actively beneficial for dental health by reducing caries cavities to a third in regular use and helpful to remineralization. Fair evidence was found that xylitol as chewing gum, lozenges, nasal spray, etc. reduced the incidence of acute middle ear infection in healthy children. Cavity-causing bacteria prefer six-carbon sugars or disaccharides, while xylitol is non-fermentable and cannot be used as an energy source - while still being taken up into the cell due to similar shape and interfering with bacterial growth and reproduction. The harmful micro-organisms are starved in the presence of xylitol, allowing the mouth to remineralize damaged teeth with less interruption. Possessing approximately 33% fewer calories, xylitol is a lower-calorie alternative to table sugar.
AdipoGen Tyramine
Chemical. CAS 51-67-2. Formula C8H11NO. MW 137.2. Synthetic. Tyramine is a naturally-occurring trace amine derived from the amino acid tyrosine that is produced endogenously or can be obtained from certain foods. Tyramine acts as a catecholamine releasing agent. It is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. Acts as a adrenergic and activates trace amine-associated receptor 1. Tyramine also inhibits the release of norepinephrine and dopamine. It is metabolized by monoamine oxidase A. Primarily used as an intermediate in the manufacture of pharmaceutical and agrochemical products.