Nucleosides
5-Methylcytidine, 98%, Thermo Scientific™
BD Bromodeoxyuridine (BrdU)
A thymidine analog used in cell proliferation studies
Fialuridine, Thermo Scientific™
STEMCELL Technologies 5-Azacytidine, Size: 50 mg
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
American Radiolabeled Chemicals Inc GTP A-33P 1LC
Guanosine 5'-a-33P triphosphate tetra (triethylammonium) salt 1mCi in 50mM tricine (pH 7.6), 10 mCi/ml, S.A. 3000 Ci/mmol, M.W. 525.18, Shipped w/o dry ice, store at 4deg.C
Cayman Chemical ArachIdonyl thIo-PC 25mg
A chromogenic substrate for many PLA2s including sPLA2, cPLA2, and iPLA2
Cayman Chemical 6-thIo-2-DeoxygunosIn 5mg
A purine nucleoside analog; reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.04 µM) but is also toxic to Calu-3 cells (CC50 = 1.14 µM); decreases tumor volume and increases the number of tumor cells with telomere dysfunction-induced foci in an A549 NSCLC mouse xenograft model at 2 mg/kg; increases the number of PD-1+ CD8+ T cells, as well as induces tumor regression when administered in combination with anti-PD-L1 in MC-38 murine colon carcinoma models
Sigma Aldrich Fine Chemicals Biosciences Nucleoside 5-Diphosphate K
Nucleoside Diphosphate Kinase exists in two isoforms in eukaryotic cells NDK-A and NDK-B. These enzymes are found expressed both in the mitochondria and the cytoplasm.
Chem-Impex International, Inc. Inosine-5'-diphosphate trisodium salt | MFCD00043058 | 100MG
Inosine-5'-diphosphate trisodium salt, MFCD00043058, 100MG