It has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).ChEBI : Not available.Crystal_Structure : Not available.InChI : Not available.InChIKey : Not available.RTECS Number: AU7480500
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N1-Methylpseudo-UTP (sodium salt) is a modified nucleotide analog utilized as a substrate for enzymatic in vitro transcription reactions aimed at generating messenger RNA (mRNA) molecules for biomedical research This nucleotide contains the N1-methylpseudouridine base modification which helps to reduce innate immune system activation triggered by exogenous mRNA transcripts within mammalian cells Incorporating N1-methylpseudo-UTP into synthetic transcripts decreases recognition by intracellular pattern-recognition receptors thereby lowering innate immune responses and enhancing cellular tolerance upon transfection Consequently N1-methylpseudo-UTP incorporation has been actively employed in developing mRNA constructs for therapeutic applications such as vaccine development protein replacement therapies and gene-editing platforms
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