Nucleotides
Apexbio Technology LLC 2-Thio-UTP(Synonyms: 2-Thiouridine-5'-triphosphate, 2-Thio-uridine triphosphate, 2-S-UTP, 2-Thio-UTP sodium salt), 50ul (100 mM).
2-Thio-UTP is a base-modified ribonucleoside triphosphate commonly used in RNA-based biomedical research Incorporation of 2-Thio-UTP into RNA transcripts reduces innate immune activation compared to unmodified RNA Mechanistically RNAs transcribed with 2-Thio-UTP lack the ability to activate RNA-dependent protein kinase (PKR) markedly diminish 2 -5 -oligoadenylate synthetase (OAS) pathway induction decrease recognition by retinoic acid-inducible gene I (RIG-I) and suppress Toll-like receptor (TLR) mediated signaling Thus 2-Thio-UTP serves as a research tool in studies designing low-immunogenic RNAs for therapeutic applications
Apexbio Technology LLC Cyanine 3-AA-CTP(Synonyms: Cy3-AA-CTP, Cy3-labeled CTP, Cyanine 3-labeled cytidine triphosphate), 5ul (10 mM).
Cyanine 3-AA-CTP is a fluorescently labeled cytidine triphosphate derivative conjugated with the fluorophore Cy3 During in vitro transcription reactions Cyanine 3-AA-CTP is enzymatically incorporated into RNA strands producing Cy3-labeled RNA molecules suitable for fluorescence-based analyses Due to Cy3 s high fluorescence intensity and photostability the labeledRNAs facilitate diverse studies such as fluorescence microscopy imaging RNA-protein interaction assays and sensitive RNA detection methodologies Consequently Cyanine 3-AA-CTP serves as an important reagent for investigating RNA biology and function
Apexbio Technology LLC Aminoallyl-dUTP(Synonyms: 5-(3-Aminoallyl)-2'-deoxyuridine-5'-triphosphate, AA-dUTP, Aminoallyl-2'-deoxyuridine triphosphate), 100ul (10mM), CAS: 116840-18-7.
Aminoallyl-dUTP (CAS 116840-18-7) is a modified deoxynucleotide designed for indirect covalent labeling of DNA or cDNA in molecular biology research Structurally analogous to natural dTTP it incorporates into DNA via enzymatic reactions including PCR (Taq polymerase) nick translation primer extension (Klenow exo-) terminal labeling (TdT) and reverse transcription (MMLV RT) The introduced primary amine moiety enables subsequent conjugation to NHS-activated labels such as fluorophores for fluorescence microscopy or biotin for affinity-based purification and detection strategies including in situ hybridization
Cayman Chemical Caspase4 InhIbItrAcLEVD 25uL
A GCGR antagonist reduces glucagon-induced hyperglycemia in wild-type mice reduces blood glucose levels in mouse models of diabetes
Apexbio Technology LLC 2-Thio-UTP(Synonyms: 2-Thiouridine-5'-triphosphate, 2-Thio-uridine triphosphate, 2-S-UTP, 2-Thio-UTP sodium salt), 100ul (100 mM).
2-Thio-UTP is a base-modified ribonucleoside triphosphate commonly used in RNA-based biomedical research Incorporation of 2-Thio-UTP into RNA transcripts reduces innate immune activation compared to unmodified RNA Mechanistically RNAs transcribed with 2-Thio-UTP lack the ability to activate RNA-dependent protein kinase (PKR) markedly diminish 2 -5 -oligoadenylate synthetase (OAS) pathway induction decrease recognition by retinoic acid-inducible gene I (RIG-I) and suppress Toll-like receptor (TLR) mediated signaling Thus 2-Thio-UTP serves as a research tool in studies designing low-immunogenic RNAs for therapeutic applications
eMolecules Uridine-5'-triphosphate trisodium salt dihydrate | 116295-90-0 | MFCD00150714 | 1g
Apollo Scientific | Uridine-5'-triphosphate trisodium salt dihydrate | 1g | 562456501 | BIU0402 | | 116295-90-0 | MFCD00150714 | 586.115 | C9H16N2Na3O17P3
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Enzo Life Sciences Plate (clear) (5x96wells)
Quantity: Five 1/2 volume clear, flat-bottom 96-well assay plates. Long Term Storage: .
Sigma Aldrich Fine Chemicals Biosciences Nicotinic acid adenine dinucleotide phosphate sodium salt >=92.5% | 5502-96-5 | MFCD00274064 | 25MG
Nicotinic acid adenine dinucleotide phosphate sodium salt >=92.5% | Purity: >=92.5% | 5502-96-5 | MFCD00274064 | 25MG
Cayman Chemical N6- 2-IsopentenyladenIn 500mg
A naturally occurring cytokinin that regulates cell division, development, and nutrient processing in plants and serves as a precursor to zeatin synthesis
Enzo Life Sciences 8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphate . sodium salt (5mg). CAS: 51239-26-0
Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels. Higher activation potential as compared to cGMP; excellent cell membrane permeability and phosphodiesterase stability. Preferred alternative to unsuitable analogs such as dibutyryl-cGMP. Alternative name: 8-pCPT-cGMP . Na. Purity: ≥99% (HPLC). Solubility: Soluble in water. Long Term Storage: -20°C.