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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
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2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP) is a mononucleotide that has guanine as its nucleobase. This compound acts as a reactant in the analysis of self-assembling solutions and the nucleation/growth of G-quadruplexes. It is also involved in nucleophilic trapping and reductive alkylation processes. As a nucleic acid guanosine triphosphate (GTP) derivative, it serves as a nucleotide precursor in DNA synthesis.
Reactant in analysis of self-assembling solutions
Reactant in nucleation and growth of G-quadruplexes
Used in nucleophilic trapping
Used in reductive alkylation
Functions as an oxidizable target
Serves as a nucleotide precursor in DNA synthesis
Suitable for evaluating biologically relevant photosensitizing properties
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CTP inhibitor (Compound 792949) is a research-grade small molecule that selectively inhibits the plasma membrane citrate transporter (PMCT/CTP). It is supplied as a high-purity solid for use in biochemical and cell-based studies of citrate transport and metabolism.
Potent and selective inhibitor of the plasma membrane citrate transporter.
High purity (98.0%) suitable for in vitro research.
Supplied as a solid; also available as 10 mM solution in DMSO.
Multiple size options, including 25 mg.
Storage: store at 4°C protected from light; in solvent, -80°C (6 months), -20°C (1 month).
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5-Propargylamino-dCTP is an alkyne-modified deoxycytidine triphosphate designed for incorporation into DNA and subsequent conjugation using click chemistry. It is intended for research applications requiring sensitive nucleic acid labeling and high chemical purity.
Alkyne-modified nucleotide for bioorthogonal conjugation.
Enables click chemistry labeling of incorporated nucleotides.
High purity suitable for molecular biology assays.
Water soluble at high concentration for convenient formulation.
Stable when stored frozen; follow sealed, moisture-free storage.
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Digoxigenin (DIG) -11-uridine triphosphate (UTP) is provided as a SOLUTIONon of the tetralithium salt in 3.5mM (200nmol) or 10mM (250nmol) concentration. It is used as a substrate for SP6 T3 and T7 RNA polymerases. It can replace UTP in the in vitro transcription reaction for DIG labeling of RNA in a ratio of 3565%.
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This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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