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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
MW 546 Da, Purity >95%. Non-hydrolyzable GTP analog. Has an amine group in place of an oxygen atom. Potent adenylate cyclase stimulator. Binds tightly to G-protein in the presence of Mg²+. Forms stable Ras complexes.
Advantage UltraPure PCR Nucleotide Mix, which contains all four dNTPs in a premixed aqueous solution, is ready for use in PCR amplification, cDNA synthesis, and in vitro mutagenesis. 4 x 100 uL
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This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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