RNAi and RNA Reagents
ABclonal Technology PI3 Kinase p110 beta
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K) These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB) PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection Alternative splicing results in multiple transcript variants
ABclonal Technology KO Validated LKB1 Rabbit mAb
The protein encoded by this gene is a serine threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome as well as with skin pancreatic and testicular cancers
Apexbio Technology LLC EZ Cap EGFP mRNA (m1Ψ) 5x1mg (1mg/mL)
Enhanced green fluorescent protein (EGFP) is a commonly used reporter molecule that emits intense and bright green fluorescence upon excitation EZ CapTM EGFP mRNA (m1 ) is provided at a concentration of approximately 1 mg/mL It features a Cap 1 structure generated through co-transcriptional capping which is more suitable for mammalian systems and offers higher transcription efficiency compared to Cap 0 structures (ARCA and mCap) Incorporation of N1-Methylpseudo-UTP (m1 ) and a poly (A) tail helps suppress RNA-mediated innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo Additionally the poly (A) tail plays a crucial role in enhancing the efficiency of translation initiation
Cayman Chemical BLT2 Receptr PolycLNal ntI 1ea
Immunogen: peptide from the C-terminal region of human BLT2 • Host: Rabbit • Species Reactivity: (+) Human and mouse • Application(s): WB
Cayman Chemical EP Receptr asy Prostaglnd 20uL
An ionizable cationic lipid (pKa 6.39) has been used in the generation of LNPs for siRNA delivery in vitro and in vivo LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter decrease viability of HepG2 cells LNPs containing O12-D3-I3 and an mRNA reporter selectively accumulate in the tumor and liver over the lungs kidneys spleen and heart in mice LNPs containing O12-D3-I3 and encapsulating ferrocene and siRNA targeting Nrf2 or system xc- cystine/glutamate transporter reduce tumor growth and volume in an MCF-7 breast cancer mouse xenograft model LNPs containing O12-D3-I3 and encapsulating siRNA targeting Factor VII decrease hepatocyte Factor VII mRNA levels in mice
Cayman Chemical ATG5 MoncLNal ANTIBDYClo 100ug
Immunogen: Full-length human recombinant ATG5 protein • Host: Mouse • Species Reactivity: (+) Human • Cross Reactivity: (-) ATG8 • Applications: ELISA, IF
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS HUMAN ME3 SIRNA
ON-TARGETplus Human ME3 siRNA SMART pool
