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Short/small hairpin RNA (shRNA) is an artificial RNA molecule with a tight hairpin turn used to silence target gene expression via RNA interference (RNAi). Cells can be made to express shRNA through the introduction of plasmids or viral/bacterial vectors.
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This adenovirus contains a scrambled shRNA sequence which is under the control of a CMV promoter. It also have the GFP expression under another CMV promoter.
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