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Short/small hairpin RNA (shRNA) is an artificial RNA molecule with a tight hairpin turn used to silence target gene expression via RNA interference (RNAi). Cells can be made to express shRNA through the introduction of plasmids or viral/bacterial vectors.
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The OriGene Technologies TR30021V5 is a lentiviral control particle that functions as a negative control in shRNA experiments, featuring a GFP label for easy visualization. Engineered with a puromycin resistance gene, it allows efficient selection of transduced mammalian cells. This product aids in optimizing multiplicity of infection (MOI), providing researchers with essential tools for successful gene delivery.
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This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.
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200 ul frozen viral stock containing 1 x 10^6 infectious units of virus (IFU), sufficient for 10-20 transductions. Suitable as a negative control for experiments using targeted shRNA Lentiviral Particles DNA transduction. Encodes of a scrambled shRNA sequence that will not lead to the specific degradation of any cellular message. After transduction, cells stably expressing the control shRNA may be isolated via puromycin selection.
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The protein encoded by this gene is a member of the dual specificity protein kinase family which acts as a mitogen-activated protein (MAP) kinase kinase MAP kinases also known as extracellular signal-regulated kinases (ERKs) act as an integration point for multiple biochemical signals This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals As an essential component of MAP kinase signal transduction pathway this kinase is involved in many cellular processes such as proliferation differentiation transcription regulation and development
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More