Knockdown your target gene function with confidenceThe patented modification pattern for specificity, combined with the SMARTselection algorithm for efficient, guaranteed target gene silencing, makes ON-TARGETplus siRNA the premium choice for optimal knockdown and reduced off-targets.Available as pre-designed, genome-wide reagents for human, mouse and rat.Off-targets reduced by up to 90% compared to unmodified siRNAGuaranteed silencing by SMARTpool and 3 of 4 individual siRNAs (see Guarantee tab)Sequence information provided with siRNA purchase