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Complete and incomplete formulations of Freund's and alum-based adjuvants to mix and emulsify with processed immunogens; for use in the preparation and subcutaneous or intravenous injection of immunization agents into animals for efficient antibody production.
Used to prepare antigen-adjuvant emulsions. BD™ Difco™ Adjuvants are used in immunological studies with laboratory animals. (Not intended for human or therapeutic use.)
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Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
FastAb Adjuvant is a novel, water-soluble mouse adjuvant designed specifically for preparing monoclonal and polyclonal antibodies. It can be used as an alternative to the classic Freund's adjuvant.
Alum Adjuvant is insoluble white colloidal suspension of aluminum hydroxide used to potentiate immune response. Antigen adsorbs on the aluminum hydroxide precipitate and when injected form a depot of insoluble antigen at injection site which attracts immune cells and enhance immune response.
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Alhydrogel adjuvant 2% is an aluminium hydroxide (referred to as alum) wet gel suspension. Alum acts primarily through the formation of a depot at the injection site, enabling enhanced antigen availability, activation of antigen presenting cells (APCs) and uptake by immune cells. It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs). The NLR pathway has been recently described as an important mechanism in alum adjuvancy. Alum has been shown to activate the NLRP3 inflammasome although its role in alum-induced antibody response is controversial. 21645-51-2.
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The TLR4 agonist, MPLA (monophosphoryl lipid A) is a derivative of lipid A from Salmonella minnesota R595 lipopolysaccharide (LPS or endotoxin). MPLA is considerably less toxic than LPS whilst maintaining immunostimulatory activity.
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