Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ Adenine
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CAS: 2922-28-3 Molecular Formula: C5H6ClN5
| CAS | 2922-28-3 |
|---|---|
| Molecular Formula | C5H6ClN5 |
Tocris Bioscience™ WAY 181187 oxalate
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High affinity and selective 5-HT6 agonist
| Target | 5-HT6 Receptor Agonists |
|---|---|
| CAS | 1883548-85-3 |
| Purity | >98% |
| Chemical Name or Material | 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C15H13ClN4O2S2.C2H2O4 |
| Formula Weight | 470.91 |
Tocris Bioscience™ HU 308
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CAS: 256934-39-1 Molecular Formula: C27H42O3
| CAS | 256934-39-1 |
|---|---|
| Molecular Formula | C27H42O3 |
Tocris Bioscience™ Mirtazapine
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CAS: 85650-52-8 Molecular Formula: C17H19N3
| CAS | 85650-52-8 |
|---|---|
| Molecular Formula | C17H19N3 |
Tocris Bioscience™ 3-Deazaneplanocin A hydrochloride
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CAS: 120964-45-6 Molecular Formula: C12H15ClN4O3
| CAS | 120964-45-6 |
|---|---|
| Molecular Formula | C12H15ClN4O3 |
Tocris Bioscience™ DDR1-IN-1 dihydrochloride
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Selective DDR1 inhibitor
| Inhibitors | DDR1-IN-1 dihydrochloride |
|---|---|
| CAS | 1780303-76-5 |
| Product Type | DDR1-IN-1 dihydrochloride |
| Molecular Weight (g/mol) | 625.51 |
| Purity | >98% |
Tocris Bioscience™ L-NMMA acetate
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CAS: 53308-83-1 Molecular Formula: C9H20N4O4
| CAS | 53308-83-1 |
|---|---|
| Molecular Formula | C9H20N4O4 |
Tocris Bioscience™ Rostafuroxin
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Na+/K+ ATPase modulator; antihypertensive agent
| Target | Na+/K+ ATPase Modulators |
|---|---|
| CAS | 156722-18-8 |
| Purity | >98% |
| Chemical Name or Material | 3β,5β,14β)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol |
| Recommended Storage | Store at 4°C |
| Synonym | PST 2238 |
| Molecular Formula | C23H34O4 |
| Formula Weight | 374.51 |
Tocris Bioscience™ CyPPA
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KCa2.2 and KCa2.3 (SK) channel activator
| CAS | 73029-73-9 |
|---|---|
| Chemical Name or Material | N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H23N5 |
| Formula Weight | Observed MW: 285.39 |
| Assay Percent Range | >99% |
Tocris Bioscience™ PSB CB5
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Selective GPR18 antagonist
| Target | Additional Cannabinoid-related Compounds |
|---|---|
| CAS | 1627710-30-8 |
| Purity | 98% |
| Chemical Name or Material | (2 Z)-2 [[3-[(4-Chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5 H-imidazo[2,1-b][1,3 ]thiazin-3(2 H)-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H17ClN2O2S |
Tocris Bioscience™ PB 28 dihydrochloride
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High affinity σ2 agonist
| CAS | 172907-03-8 |
|---|---|
| Solubility | Soluble to 20mM with gentle warming in water |
| Chemical Name or Material | 1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride |
| Recommended Storage | Desiccate at +4°C |
| Molecular Formula | C24H38N2O.2HCl |
| Formula Weight | Observed MW: 443.5 |
| Assay Percent Range | >99% |
Tocris Bioscience™ Ro 20-1724
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CAS: 29925-17-5 Molecular Formula: C15H22N2O3
| CAS | 29925-17-5 |
|---|---|
| Molecular Formula | C15H22N2O3 |
Tocris Bioscience™ Janelia Fluor 669, SE
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Far red dye (Reactive group: NHS ester). Applications: super resolution microscopy e.g. dSTORM & STED, confocal and live cell imaging
Tocris Bioscience™ NSC 617145
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Werner syndrome helicase (WRN) inhibitor
| CAS | 203115-63-3 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 20mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | NSC 617145 |
| Recommended Storage | Store at -20°C |
| Synonym | 1,1'-(2,2-Dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione |
| Molecular Formula | C13H10Cl4N2O4 |
| Formula Weight | 400.04 |
Tocris Bioscience™ Ruxolitinib
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Potent and selective JAK1/JAK2 inhibitor; orally bioavailable