Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,741
Tocris Bioscience™ TCS OX2 29
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CAS: 1610882-30-8 Molecular Formula: C23H32ClN3O3
| CAS | 1610882-30-8 |
|---|---|
| Molecular Formula | C23H32ClN3O3 |
1,742
Tocris Bioscience™ IN 1130
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Potent and selective inhibitor of TGF-βRI
1,743
Tocris Bioscience™ NVS PAK1 1
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Potent and selective PAK1 inhibitor
| CAS | 1783816-74-9 |
|---|---|
| Chemical Name or Material | (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H25ClF3N5O |
| Formula Weight | Observed MW: 479.93 |
| Assay Percent Range | >98% |
1,744
Tocris Bioscience™ PD 4'-piperazine
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Stable cereblon ligand, for PROTAC synthesis
1,745
Tocris Bioscience™ PF 573228
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CAS: 869288-64-2 Molecular Formula: C22H20F3N5O3S
| CAS | 869288-64-2 |
|---|---|
| Molecular Formula | C22H20F3N5O3S |
1,746
Tocris Bioscience™ BTT 3033
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Selective inhibitor of integrin α2β1
| Inhibitors | BTT 3033 |
|---|---|
| Product Type | BTT 3033 |
| Molecular Weight (g/mol) | 465.5 |
| Purity | >98% |
1,747
Tocris Bioscience™ Ferrostatin 1
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Selective inhibitor of erastin induced ferroptosis
| Inhibitors | Ferrostatin 1 |
|---|---|
| Product Type | Ferrostatin 1 |
| Molecular Weight (g/mol) | 262.35 |
| Purity | >98% |
1,748
Tocris Bioscience™ GSK 343
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Potent and selective SAM-competitive EZH2 inhibitor
1,749
Tocris Bioscience™ CGP 3466B maleate
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CAS: 200189-97-5 Molecular Formula: C23H21NO5
| CAS | 200189-97-5 |
|---|---|
| Molecular Formula | C23H21NO5 |
1,750
Tocris Bioscience™ LaKe
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Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells
1,751
Tocris Bioscience™ NS 8593 Hydrochloride
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Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
| CAS | 875755-24-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | NS 8593 hydrochloride |
| Recommended Storage | Store at 4°C |
| Synonym | N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride |
| Molecular Formula | C17H17N3·HCl |
| Formula Weight | 299.8 |
1,752
Tocris Bioscience™ SB 612111 hydrochloride
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Selective NOP antagonist
| Inhibitors | SB 612111 hydrochloride |
|---|---|
| Product Type | SB 612111 hydrochloride |
| Molecular Weight (g/mol) | M.W. (Observed): 454.86 |
| Purity | 97% |
| Recommended Storage | -20°C |
| Molecular Formula | (5 S,7 S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5 H-benzocyclohepten-5-ol hydrochloride |
1,753
Tocris Bioscience™ JBJ-03-142-02
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Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
1,754
Tocris Bioscience™ ANR 94
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CAS: 634924-89-3 Molecular Formula: C9H13N5O
| CAS | 634924-89-3 |
|---|---|
| Molecular Formula | C9H13N5O |
1,755
Tocris Bioscience™ SF 11
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CAS: 443292-81-7 Molecular Formula: C27H30N2O2S
| CAS | 443292-81-7 |
|---|---|
| Molecular Formula | C27H30N2O2S |