Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ DDR1-IN-1 dihydrochloride
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Selective DDR1 inhibitor
| Inhibitors | DDR1-IN-1 dihydrochloride |
|---|---|
| CAS | 1780303-76-5 |
| Product Type | DDR1-IN-1 dihydrochloride |
| Molecular Weight (g/mol) | 625.51 |
| Purity | >98% |
Tocris Bioscience™ L-371,257
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CAS: 162042-44-6 Molecular Formula: C28H33N3O6
| CAS | 162042-44-6 |
|---|---|
| Molecular Formula | C28H33N3O6 |
Tocris Bioscience™ GSK 264220A
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CAS: 685506-42-7 Molecular Formula: C17H21N3O4S
| CAS | 685506-42-7 |
|---|---|
| Molecular Formula | C17H21N3O4S |
Tocris Bioscience™ ESI 1
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Selective HDAC3 inhibitor; also myelination inducer
| Target | Class I Histone Deacetylases Inhibitors |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(2-Aminophenyl)-5-[(phenylmethyl)amino]-2-pyrazinecarboxamide dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H17N5O.2HCl |
Tocris Bioscience™ API-2
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Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
Tocris Bioscience™ Atipamezole hydrochloride
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CAS: 104075-48-1 Molecular Formula: C14H17ClN2
| CAS | 104075-48-1 |
|---|---|
| Molecular Formula | C14H17ClN2 |
Tocris Bioscience™ L-NMMA acetate
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CAS: 53308-83-1 Molecular Formula: C9H20N4O4
| CAS | 53308-83-1 |
|---|---|
| Molecular Formula | C9H20N4O4 |
Tocris Bioscience™ A 784168
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CAS: 824982-41-4 Molecular Formula: C19H15F6N3O3S
| CAS | 824982-41-4 |
|---|---|
| Molecular Formula | C19H15F6N3O3S |
Tocris Bioscience™ U 73122
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CAS: 112648-68-7 Molecular Formula: C29H40N2O3
| CAS | 112648-68-7 |
|---|---|
| Molecular Formula | C29H40N2O3 |
Tocris Bioscience™ SB 204990
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ATP citrate lyase (ACLY) inhibitor
| Inhibitors | SB 204990 |
|---|---|
| Product Type | SB 204990 |
| Molecular Weight (g/mol) | 389.27 |
| Purity | >98% |
Tocris Bioscience™ BGC 20-761
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Tocris Bioscience™ Flumazenil
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CAS: 78755-81-4 Molecular Formula: C15H14FN3O3
| CAS | 78755-81-4 |
|---|---|
| Molecular Formula | C15H14FN3O3 |
Tocris Bioscience™ Thalidomide 4'-ether-PEG2-azide
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
Tocris Bioscience™ Rostafuroxin
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Na+/K+ ATPase modulator; antihypertensive agent
| Target | Na+/K+ ATPase Modulators |
|---|---|
| CAS | 156722-18-8 |
| Purity | >98% |
| Chemical Name or Material | 3β,5β,14β)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol |
| Recommended Storage | Store at 4°C |
| Synonym | PST 2238 |
| Molecular Formula | C23H34O4 |
| Formula Weight | 374.51 |
Tocris Bioscience™ CS 640
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Potent CaM kinase I inhibitor
| Target | CaM Kinase I |
|---|---|
| CAS | 2388506-83-8 |
| Purity | 0.98 |
| Chemical Name or Material | 2-[(3S)-3-Amino-1-piperidinyl]-4-[[2,6-bis(1-methylethyl)-4-pyridinyl]amino]-5-pyrimidinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H31N7O |