Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,311
Tocris Bioscience™ R 268712
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective inhibitor of TGF-βRI
| Inhibitors | R 268712 |
|---|---|
| Product Type | R 268712 |
| Molecular Weight (g/mol) | 363.39 |
| Purity | >98% |
2,312
Tocris Bioscience™ CP 93129 dihydrochloride
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CAS: 879089-64-2 Molecular Formula: C12H17Cl2N3O2
| CAS | 879089-64-2 |
|---|---|
| Molecular Formula | C12H17Cl2N3O2 |
2,313
Tocris Bioscience™ ESI 09
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Epac inhibitor
| CAS | 263707-16-0 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | EPAC Inhibitors |
| Recommended Storage | Store at 4°C |
| Synonym | α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile |
| Molecular Formula | C16H15ClN4O2 |
| Formula Weight | 330.77 |
2,314
Tocris Bioscience™ CGP 74514 dihydrochloride
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Potent cdk1 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| Purity | >98% |
| Chemical Name or Material | rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H24ClN7.2HCl |
| Formula Weight | 458.82 |
2,315
Tocris Bioscience™ AMBMP Hydrochloride, >98%
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CAS: 2095432-75-8 Molecular Formula: C19H19ClN4O3
| CAS | 2095432-75-8 |
|---|---|
| Molecular Formula | C19H19ClN4O3 |
2,316
Tocris Bioscience™ Oxotremorine M
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CAS: 3854-04-4 Molecular Formula: C11H19IN2O
| CAS | 3854-04-4 |
|---|---|
| Molecular Formula | C11H19IN2O |
2,317
Tocris Bioscience™ Ruxolitinib phosphate
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Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
2,318
Tocris Bioscience™ Nafamostat mesylate
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CAS: 82956-11-4 Molecular Formula: C21H25N5O8S2
| CAS | 82956-11-4 |
|---|---|
| Molecular Formula | C21H25N5O8S2 |
2,319
Tocris Bioscience™ JZP 361, >99%
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Potent and selective reversible MAGL inhibitor
| CAS | 1680193-80-9 |
|---|---|
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >99% |
| Chemical Name or Material | [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- |
| Recommended Storage | Store at 4deg;C |
| Formula Weight | 405.88 |
2,320
Tocris Bioscience™ endo-IWR 1
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CAS: 1127442-82-3 Molecular Formula: C25H19N3O3
| CAS | 1127442-82-3 |
|---|---|
| Molecular Formula | C25H19N3O3 |
2,321
Tocris Bioscience™ MRS 2500 tetraammonium salt
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Highly potent and selective P2Y1 antagonist
2,322
Tocris Bioscience™ PI 103 hydrochloride
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CAS: 371935-79-4 Molecular Formula: C19H17ClN4O3
| CAS | 371935-79-4 |
|---|---|
| Molecular Formula | C19H17ClN4O3 |
2,323
Tocris Bioscience™ DMH-1
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CAS: 1206711-16-1 Molecular Formula: C24H20N4O
| CAS | 1206711-16-1 |
|---|---|
| Molecular Formula | C24H20N4O |
2,324
Tocris Bioscience™ 6,8-Bis(benzylthio)octanoic acid
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PDH and KGDH inhibitor
| Target | Dehydrogenase Inhibitors |
|---|---|
| CAS | 95809-78-2 |
| Purity | >99% |
| Chemical Name or Material | 6,8-Bis[(phenylmethyl)thio]octanoic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H28O2S2 |
| Formula Weight | 388.59 |
2,325
Tocris Bioscience™ SirReal 2
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Selective inhibitor of SIRT2
| Product Type | SirReal 2 |
|---|---|
| Molecular Weight (g/mol) | 420.55 |
| Purity | >98% |