Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ Dynapyrazole A
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Hedgehog signaling inhibitor; dynein inhibitor
| Target | Hedgehog Signaling Inhibitors |
|---|---|
| CAS | 2226517-75-3 |
| Purity | 98% |
| Chemical Name or Material | 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H12ClIN4O |
Tocris Bioscience™ Saracatinib
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Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
Tocris Bioscience™ PZ 3022
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PanK Activator
| Target | Enzyme Activators |
|---|---|
| CAS | 2170608-85-0 |
| Purity | 0.98 |
| Chemical Name or Material | 6-[4-[2-(4-Cyclopropylphenyl)acetyl]-1-piperazinyl]-3-pyridazinecarbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H21N5O |
Tocris Bioscience™ IT1t dihydrochloride
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CAS: 1092776-63-0 Molecular Formula: C21H36Cl2N4S2
| CAS | 1092776-63-0 |
|---|---|
| Molecular Formula | C21H36Cl2N4S2 |
Tocris Bioscience™ IB-MECA
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CAS: 152918-18-8 Molecular Formula: C18H19IN6O4
| CAS | 152918-18-8 |
|---|---|
| Molecular Formula | C18H19IN6O4 |
Tocris Bioscience™ Fluticasone propionate
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CAS: 80474-14-2 Molecular Formula: C25H31F3O5S
| CAS | 80474-14-2 |
|---|---|
| Molecular Formula | C25H31F3O5S |
Tocris Bioscience™ TB 21007
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CAS: 207306-50-1 Molecular Formula: C15H17NO2S3
| CAS | 207306-50-1 |
|---|---|
| Molecular Formula | C15H17NO2S3 |
Tocris Bioscience™ CU-T12-9
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Potent TLR1/2 agonist
| CAS | 1821387-73-8 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >99% |
| Physical Form | Solid |
| Chemical Name or Material | CU-T12-9 |
| Recommended Storage | Store at 4°C |
| Synonym | N-Methyl-4-nitro-2-(4-(4-trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline |
| Molecular Formula | C17H13F3N4O2 |
| Formula Weight | 362.31 |
Tocris Bioscience™ SAG
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Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
| Inhibitors | SAG |
|---|---|
| Product Type | SAG |
| Molecular Weight (g/mol) | 490.06 |
| Purity | >99% |
Tocris Bioscience™ NX 2127
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Potent BTK Degrader (PROTAC™)
Tocris Bioscience™ Maraviroc
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CAS: 376348-65-1 Molecular Formula: C29H41F2N5O
| CAS | 376348-65-1 |
|---|---|
| Molecular Formula | C29H41F2N5O |
Tocris Bioscience™ SR 141716A
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Selective CB1 inverse agonist
Tocris Bioscience™ D-Serine
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CAS: 312-84-5 Molecular Formula: C3H7NO3
| CAS | 312-84-5 |
|---|---|
| Molecular Formula | C3H7NO3 |
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Tocris Bioscience™ SD 208
Tocris Bioscience™ SD 208
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CAS: 627536-09-8 Molecular Formula: C17H10ClFN6
| CAS | 627536-09-8 |
|---|---|
| Molecular Formula | C17H10ClFN6 |
Tocris Bioscience™ Lisuride maleate
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CAS: 19875-60-6 Molecular Formula: C24H30N4O5
| CAS | 19875-60-6 |
|---|---|
| Molecular Formula | C24H30N4O5 |