Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ GSK 2795039
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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NADPH oxidase 2 (NOX2) inhibitor
| Target | NADPH Oxidase Inhibitors |
|---|---|
| CAS | 1415925-18-6 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H26N6O2S |
Tocris Bioscience™ Dinaciclib
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 779353-01-4 |
| Purity | 0.98 |
| Chemical Name or Material | (2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H28N6O2 |
Tocris Bioscience™ MS 39
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective VHL-recruiting Degrader (PROTAC™) of mutant EGFR
Tocris Bioscience™ PEAQX tetrasodium salt
Greener Choice
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Small and Specialty Supplier Partner
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Potent and GluN2A-selective NMDA antagonist
Tocris Bioscience™ Lac-Phe
Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 183241-73-8 |
| Purity | 0.95 |
| Chemical Name or Material | N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C12H15NO4 |
Tocris Bioscience™ BDY FL, SE
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Green BDY (BODIPY™ or boron-dipyrromethene) fluorescent dye for the labeling of amines; supplied as NHS ester
Tocris Bioscience™ TokeOni
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Small and Specialty Supplier Partner
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Near-infrared red (NIR)-emission luciferin analog
| CAS | 1429881-91-3 |
|---|---|
| Molecular Formula | C28H40N6O |
Canertinib dihydrochloride, Thermo Scientific™
CAS: 289499-45-2 Molecular Formula: C24 H25 Cl F N5 O3 · 2 H Cl
| CAS | 289499-45-2 |
|---|---|
| Molecular Formula | C24 H25 Cl F N5 O3 · 2 H Cl |
Tocris Bioscience™ b-Cyclodextrin
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Small and Specialty Supplier Partner
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Cyclic complexing agent
Tocris Bioscience™ GSK 2256098
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent focal adhesion kinase (FAK) inhibitor
| Target | Focal Adhesion Kinase Inhibitors |
|---|---|
| CAS | 1224887-10-8 |
| Purity | 0.98 |
| Chemical Name or Material | 2-[[5-Chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl]amino]-N-methoxybenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H23ClN6O2 |
Tocris Bioscience™ STING Degrader N-Me-SP23
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Negative control for STING Degrader SP23 (Cat. No. 8053)