Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ CGP 3466B maleate
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CAS: 200189-97-5 Molecular Formula: C23H21NO5
| CAS | 200189-97-5 |
|---|---|
| Molecular Formula | C23H21NO5 |
Tocris Bioscience™ Belinostat
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Potent pan-HDAC inhibitor
| Target | Histone Deacetylase Inhibitors |
|---|---|
| CAS | 866323-14-0 |
| Purity | 98% |
| Chemical Name or Material | (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H14N2O4S |
Tocris Bioscience™ DCG IV
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Highly potent group II mGlu agonist; also NMDA agonist
| Target | Group II mGluR Agonists |
|---|---|
| CAS | 147782-19-2 |
| Solubility | Soluble to 100mM in water |
| Purity | 98% |
| Chemical Name or Material | (2 S,2 'R,3 'R)-2-(2 ',3 '-Dicarboxycyclopropyl)glycine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C7H9NO6 |
| Formula Weight | Observed MW: 203.15 |
| Assay Percent Range | >98% |
Tocris Bioscience™ SNC 80
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CAS: 156727-74-1 Molecular Formula: C28H39N3O2
| CAS | 156727-74-1 |
|---|---|
| Molecular Formula | C28H39N3O2 |
Tocris Bioscience™ SB 277011A dihydrochloride
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CAS: 1226917-67-4 Molecular Formula: C28H32Cl2N4O
| CAS | 1226917-67-4 |
|---|---|
| Molecular Formula | C28H32Cl2N4O |
Tocris Bioscience™ dTAG Janelia Fluor™ 525
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Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) labeled proteins
Tocris Bioscience™ LRRK2-IN-1
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CAS: 1234480-84-2 Molecular Formula: C31H38N8O3
| CAS | 1234480-84-2 |
|---|---|
| Molecular Formula | C31H38N8O3 |
Tocris Bioscience™ GSK 2795039
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NADPH oxidase 2 (NOX2) inhibitor
| Target | NADPH Oxidase Inhibitors |
|---|---|
| CAS | 1415925-18-6 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H26N6O2S |
Tocris Bioscience™ Psoralen-triethylene glycol azide
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RNA conformation probe; reagent for COMRADES RNA platform
Tocris Bioscience™ Flumazenil
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CAS: 78755-81-4 Molecular Formula: C15H14FN3O3
| CAS | 78755-81-4 |
|---|---|
| Molecular Formula | C15H14FN3O3 |
Tocris Bioscience™ PSEM 308 hydrochloride
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3.HCl |
| Formula Weight | 303.83 |
Tocris Bioscience™ LY 2886721 Hydrochloride
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Potent and selective β-secretase (BACE) inhibitor
| Target | Additional Synthetic Protease Inhibitors |
|---|---|
| CAS | 1262036-49-6 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-[(4 AS,7 AS)-2-Amino-4 A,5-dihydro-4 H-furo[3,4-d][1,3 ]thiazin-7 A(7 H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H16F2N4O2S.HCl |
Tocris Bioscience™ Levcromakalim
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CAS: 94535-50-9 Molecular Formula: C16H18N2O3
| CAS | 94535-50-9 |
|---|---|
| Molecular Formula | C16H18N2O3 |
Tocris Bioscience™ NPE-caged-proton
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CAS: 1186195-63-0 Molecular Formula: C8H8NNaO6S
| CAS | 1186195-63-0 |
|---|---|
| Molecular Formula | C8H8NNaO6S |
Tocris Bioscience™ Tomoxetine hydrochloride
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CAS: 82248-59-7 Molecular Formula: C17H22ClNO
| CAS | 82248-59-7 |
|---|---|
| Molecular Formula | C17H22ClNO |