Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,971
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2,971
Tocris Bioscience™ UCB 35625
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CAS: 202796-42-7 Molecular Formula: C30H37Cl2IN2O2
| CAS | 202796-42-7 |
|---|---|
| Molecular Formula | C30H37Cl2IN2O2 |
2,972
Tocris Bioscience™ ICA 069673
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KV7.2/KV7.3 channel opener
| CAS | 582323-16-8 |
|---|---|
| Chemical Name or Material | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C11H6ClF2N3O |
| Formula Weight | Observed MW: 269.63 |
| Assay Percent Range | >99% |
2,973
Tocris Bioscience™ Remdesivir
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Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucelotide prodrug
| Target | RNA/DNA Polymerase Inhibitors |
|---|---|
| CAS | 1809249-37-3 |
| Purity | 0.98 |
| Chemical Name or Material | 2-Ethylbutyl (2 S)-2-[[-[[(2 R,3 S,4 R,5 R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H35N6O8P |
2,974
Tocris Bioscience™ AZ 191
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Potent DYRK1B inhibitor
| CAS | 1594092-37-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | AZ 191 |
| Recommended Storage | Store at -20°C |
| Synonym | N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine |
| Molecular Formula | C24H27N7O |
| Formula Weight | 429.52 |
2,975
Tocris Bioscience™ Monastrol
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CAS: 254753-54-3 Molecular Formula: C14H16N2O3S
| CAS | 254753-54-3 |
|---|---|
| Molecular Formula | C14H16N2O3S |
2,976
Tocris Bioscience™ NVS MLLT-1
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Selective MLLT1/3 inhibitor
| Target | Bromodomain Inhibitors |
|---|---|
| CAS | 2561471-13-2 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-[[(2 S)-2-Methyl-1-pyrrolidinyl]methyl]-1 H-benzimidazol-6-yl]-6-isoquinolinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H23N5O |
2,977
Tocris Bioscience™ STX 64
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Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 288628-05-7 |
| Purity | 0.98 |
| Chemical Name or Material | 6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H15NO5S |
2,978
Tocris Bioscience™ Pomalidomide 4'-alkylC3-acid
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
2,979
Tocris Bioscience™ VH 032 amide-PEG2-amine
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VH 032-PEG2-amine
2,980
Tocris Bioscience™ RHC 80267
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CAS: 83654-05-1 Molecular Formula: C20H34N4O4
| CAS | 83654-05-1 |
|---|---|
| Molecular Formula | C20H34N4O4 |
2,981
Tocris Bioscience™ L-AP5
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CAS: 79055-67-7 Molecular Formula: C5H12NO5P
| CAS | 79055-67-7 |
|---|---|
| Molecular Formula | C5H12NO5P |
2,982
Tocris Bioscience™ IEM 1460
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CAS: 121034-89-7 Molecular Formula: C19H38Br2N2
| CAS | 121034-89-7 |
|---|---|
| Molecular Formula | C19H38Br2N2 |
2,983
Tocris Bioscience™ GW 542573X
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CAS: 660846-41-3 Molecular Formula: C19H28N2O5
| CAS | 660846-41-3 |
|---|---|
| Molecular Formula | C19H28N2O5 |
2,984
Tocris Bioscience™ Purvalanol B
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CAS: 212844-54-7 Molecular Formula: C20H25ClN6O3
| CAS | 212844-54-7 |
|---|---|
| Molecular Formula | C20H25ClN6O3 |
2,985
Tocris Bioscience™ PT-65
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Potent GSK3 Degrader (PROTAC™)