Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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3,001
Tocris Bioscience™ IND 1316
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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AMPK activator
| Target | AMPK Activators |
|---|---|
| CAS | 1888473-12-8 |
| Purity | 0.98 |
| Chemical Name or Material | 3-[3-(Phenylmethoxy)phenyl]-1 H-indole-2-carboxylic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H17NO3 |
3,002
Tocris Bioscience™ Rilpivirine
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Non-nucleoside reverse transcriptase inhibitor
| Target | RNA/DNA Polymerase Inhibitors |
|---|---|
| CAS | 500287-72-9 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[[4-[[4-[(1 E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H18N6 |
3,003
Tocris Bioscience™ ERB 041
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CAS: 524684-52-4 Molecular Formula: C15H10FNO3
| CAS | 524684-52-4 |
|---|---|
| Molecular Formula | C15H10FNO3 |
3,004
Tocris Bioscience™ Methysergide maleate
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CAS: 129-49-7 Molecular Formula: C25H31N3O6
| CAS | 129-49-7 |
|---|---|
| Molecular Formula | C25H31N3O6 |
3,005
Tocris Bioscience™ Orlistat
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CAS: 96829-58-2 Molecular Formula: C29H53NO5
| CAS | 96829-58-2 |
|---|---|
| Molecular Formula | C29H53NO5 |
3,006
Tocris Bioscience™ GSK 2194069
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Potent human fatty acid synthase (hFASN) inhibitor
| CAS | 1332331-08-4 |
|---|---|
| Chemical Name or Material | 4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C25H24N4O3 |
| Formula Weight | Observed MW: 428.48 |
| Assay Percent Range | >99% |
3,007
Tocris Bioscience™ Perlapine
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Potent muscarinc DREADD agonist
| Target | DREADD Activators |
|---|---|
| CAS | 11-3-1977 |
| Purity | 99% |
| Chemical Name or Material | 6-(4-Methyl-1-piperazinyl)-11 H-dibenz[b,e]azepine |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C19H21N3 |
| Formula Weight | 291.39 |
3,008
Tocris Bioscience™ KG 5
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PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
| Target | Raf Kinase Inhibitors |
|---|---|
| CAS | 877874-85-6 |
| Purity | >98% |
| Chemical Name or Material | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H16F3N7OS |
| Formula Weight | 459.45 |
3,009
Tocris Bioscience™ I-BRD9
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Potent and selective BRD9 inhibitor
| Target | Bromodomain Inhibitors |
|---|---|
| CAS | 1714146-59-4 |
| Purity | >98% |
| Chemical Name or Material | 5-Ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22F3N3O3S2 |
| Formula Weight | 497.55 |
3,010
Tocris Bioscience™ Tabimorelin hemifumarate
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Potent, orally active ghrelin receptor agonist
3,011
Tocris Bioscience™ Ibutilide hemifumarate
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CAS: 122647-32-9 Molecular Formula: C44H76N4O10S2
| CAS | 122647-32-9 |
|---|---|
| Molecular Formula | C44H76N4O10S2 |
3,012
Tocris Bioscience™ Vincristine sulfate
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CAS: 2068-78-2 Molecular Formula: C46H58N4O14S
| CAS | 2068-78-2 |
|---|---|
| Molecular Formula | C46H58N4O14S |
3,013
Tocris Bioscience™ KF 38789
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CAS: 257292-29-8 Molecular Formula: C19H21NO5S
| CAS | 257292-29-8 |
|---|---|
| Molecular Formula | C19H21NO5S |
3,014
Tocris Bioscience™ Formoterol hemifumarate
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CAS: 43229-80-7 Molecular Formula: C42H52N4O12
| CAS | 43229-80-7 |
|---|---|
| Molecular Formula | C42H52N4O12 |
3,015
Tocris Bioscience™ MIRA-1
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CAS: 72835-26-8 Molecular Formula: C8H9NO4
| CAS | 72835-26-8 |
|---|---|
| Molecular Formula | C8H9NO4 |