Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Thermo Scientific Chemicals Silver proteinate, mild, ∼20% silver
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Thermo Scientific Chemicals Silver proteinate, mild, ∼20% silver
CAS: 1301199-90-5
| CAS | 1301199-90-5 |
|---|
572
Tocris Bioscience™ Thalidomide 4'-ether-alkylC2-acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
573
R&D Systems™ Cy5 Labeled Hyaluronan (Low MW)
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574
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Thermo Scientific Chemicals Idebenone
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Thermo Scientific Chemicals Idebenone
CAS: 58186-27-9 Molecular Formula: C19H30O5
| CAS | 58186-27-9 |
|---|---|
| Molecular Formula | C19H30O5 |
575
Tocris Bioscience™ Acetazolamide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Carbonic anhydrase inhibitor
576
Tocris Bioscience™ SPOP-i-6lc
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SPOP E3 ubiquitin ligase inhibitor
577
Tocris Bioscience™ OX 04528
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Highly potent and selective GPR84 agonist
| Target | Orphan 7-TM Receptor Agonists |
|---|---|
| CAS | 3028055-45-7 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H13F6NO2 |
578
Tocris Bioscience™ Pexidartinib
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Potent CSF-1R inhibitor
| Target | Additional RTK Inhibitors |
|---|---|
| CAS | 1029044-16-3 |
| Purity | 98% |
| Chemical Name or Material | N-[5-[(5-Chloro-1 H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H15ClF3N5 |
579
Tocris Bioscience™ LDN 193189
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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LDN 193189 synthesized to cGMP guidelines
| CAS | 1435934-00-1 |
|---|---|
| Purity | 99% |
580
Tocris Bioscience™ Pomalidomide 4'-alkylC5-azide
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Small and Specialty Supplier Partner
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
581
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Thermo Scientific Chemicals Ropivacaine hydrochloride
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Thermo Scientific Chemicals Ropivacaine hydrochloride
CAS: 98717-15-8 Molecular Formula: C17H26N2O·HCl
| CAS | 98717-15-8 |
|---|---|
| Molecular Formula | C17H26N2O·HCl |
582
Tocris Bioscience™ TH 1760
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Potent and selective NUDT15 hydrolase inhibitor
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 2567914-01-4 |
| Purity | 0.95 |
| Chemical Name or Material | 6-[[4-(1 H-Indol-5-ylcarbonyl)-1-piperazinyl]sulfonyl]-2(3 H)-benzoxazolone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H18N4O5S |
583
Tocris Bioscience™ CELT-211
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Small and Specialty Supplier Partner
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Fluorescent serotonin 5HT2B receptor ligand for HTS
584
Tocris Bioscience™ Neratinib
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Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
| Target | EGF Receptor Inhibitors |
|---|---|
| CAS | 698387-09-6 |
| Purity | 0.98 |
| Chemical Name or Material | (2 E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C30H29ClN6O3 |
