Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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571
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585
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571
R&D Systems™ GSK 2239633A
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent CCR4 antagonist
| CAS | 1240516-71-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide |
| Molecular Formula | C24H25ClN4O5S2 |
572
R&D Systems™ E 7820
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. α2 integrin inhibitor; anti-angiogenic
| Target | Integrin Receptor Inhibitors |
|---|---|
| CAS | 289483-69-8 |
| Purity | 98% |
| Chemical Name or Material | 3-Cyano-N-(3-cyano-4-methyl-1 H-indol-7-yl)benzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H12N4O2S |
| Formula Weight | 336.37 |
573
R&D Systems™ H 151
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. STING antagonist
| Target | STING Antagonists |
|---|---|
| CAS | 941987-60-6 |
| Purity | 98% |
| Chemical Name or Material | N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea |
| Recommended Storage | Store at 4°C |
| Synonym | ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173 |
| Molecular Formula | C17H17N3O |
| Formula Weight | 279.34 |
574
R&D Systems™ TRAM 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Chemical inducer of proximity for dTAG protein FKBPF36V and ecDHFR tags
575
R&D Systems™ Sitagliptin Phosphate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective DPP IV (DPP4) inhibitor (IC50 = 18 nM)
| CAS | 654671-78-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C16H15F6N5O.H3O4P |
| Formula Weight | 505.31 |
576
R&D Systems™ CU-76
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective inhibitor of cyclic GMP-AMP synthase (cGAS)
578
R&D Systems™ 4-Octyl Itaconate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Nrf2 activator; cell permeable
| CAS | 3133-16-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Methylenebutanedioic acid 4-octyl ester |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H22O4 |
| Formula Weight | 242.31 |
579
R&D Systems™ GSK'872
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective RIP3 kinase inhibitor
| CAS | 1346546-69-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17N3O2S2 |
| Formula Weight | 383.49 |
580
R&D Systems™ GSK 6853
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective BRPF1 inhibitor
| CAS | 1910124-24-1 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxybenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H27N5O3 |
| Formula Weight | 409.48 |
581
R&D Systems™ WNTinib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
| Target | beta-Catenin |
|---|---|
| CAS | 2770091-44-4 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H16F6N4O3 |
582
R&D Systems™ eIF4A i28
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. eIF4A inhibitor
583
R&D Systems™ JQAD1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective EP300 Degrader
584
R&D Systems™ Avagacestat
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Highly potent γ-secretase inhibitor; orally bioavailable
| CAS | 1146699-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide |
| Recommended Storage | Store at 4°C |
| Synonym | BMS-708163 |
| Molecular Formula | C20H17ClF4N4O4S |
| Formula Weight | 520.89 |
585
R&D Systems™ Z 944
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. CaV3.x blocker
| CAS | 1199236-64-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H27ClFN3O2 |
| Formula Weight | 383.89 |