Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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676
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676
Tocris Bioscience™ JNJ 1013NC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
677
Tocris Bioscience™ DA ZP1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorogenic Zn(II) sensor for isolation of stem cell derived β cells
678
Tocris Bioscience™ FSEN 1
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Induces ferroptosis; inhibits FSP1
| Target | Ferroptosis Inhibitors |
|---|---|
| CAS | 862808-01-3 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22BrN5OS |
679
Tocris Bioscience™ OGDA
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Green fluorescent D-amino acid; compatible with STED microscopy
680
Tocris Bioscience™ MS 154
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective cereblon-recruiting Degrader (PROTAC™) of mutant EGFR
681
Tocris Bioscience™ Pomalidomide 4'-PEG5-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
682
Tocris Bioscience™ HHP 9
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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BET bromodomain Degrader (PROTAC™); also potent Hedgehog pathway inhibitor
683
Tocris Bioscience™ OB-1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Stomatin-like protein-3 (STOML3) oligomerization inhibitor
| CAS | 300803-69-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H17N3O6 |
684
Tocris Bioscience™ SJ 1008066
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction
685
Tocris Bioscience™ Yoda 2
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Piezo1 channel activator
686
Tocris Bioscience™ BDY FL Lenalidomide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorescent cereblon ligand
687
Tocris Bioscience™ NDT 30805
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent NLRP3 inflammasome inhibitor
688
Tocris Bioscience™ JB 300
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Aurora A Degrader (PROTAC™;)
689
Tocris Bioscience™ FM19G11
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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HIF α-subunit inhibitor
| CAS | 329932-55-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H17N3O8 |
| Formula Weight | 463.4 |
690
Tocris Bioscience™ VAS 2870
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NADPH oxidase (Nox) inhibitor
| CAS | 722456-31-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H12N6OS |
| Formula Weight | 360.39 |