Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Color
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Quantity
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796
Tocris Bioscience™ Pexacerfont
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective CRF1 antagonist; anxiolytic
| CAS | 459856-18-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 8-(6-Methoxy-2-methyl-3-pyridinyl)-2,7-dimethyl-N-[(1R)-1-methylpropyl]pyrazolo[1,5-a]-1,3,5-triazin-4-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H24N6O |
| Formula Weight | 340.43 |
797
Tocris Bioscience™ Ambrisentan
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Selective ETA antagonist
798
Tocris Bioscience™ Avagacestat
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Highly potent γ-secretase inhibitor; orally bioavailable
| CAS | 1146699-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide |
| Recommended Storage | Store at 4°C |
| Synonym | BMS-708163 |
| Molecular Formula | C20H17ClF4N4O4S |
| Formula Weight | 520.89 |
799
Tocris Bioscience™ XMU MP 1
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Potent and selective ATP-competitive mammalian sterile 20-like kinase (MST) 1/2 inhibitor
800
Tocris Bioscience™ VH 032 amide-alkylC3-amine
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VHL ligand with alkyl linker and terminal amine for onward chemistry
802
Tocris Bioscience™ EM 163
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TIR-TIR interaction inhibitor
803
| CAS | 85650-56-2 |
|---|---|
| Molecular Formula | C17H16ClNO·C4H4O4 |
804
Tocris Bioscience™ AS 1842856
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Foxo1 inhibitor; orally bioavailable
| CAS | 836620-48-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Molecular Formula | C18H22FN3O3 |
805
Tocris Bioscience™ 6 TMR Tre
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Fluorescent trehalose conjugate for imaging bacterial cell envelope
806
Tocris Bioscience™ SJF 0628
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Potent BRAF PROTAC™
807
R&D Systems™ CMP-Cy5-Sialic Acid
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Activated Sugar
808
Tocris Bioscience™ TAC
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TERT activator
| Target | TERT |
|---|---|
| CAS | 666699-46-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-(3-Chloro-4-fluorophenyl)-4-fluoro-3,5-dimethylbenzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H12ClF2NO2S |
809
Tocris Bioscience™ WM 1119
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity KAT6A (MOZ) competitive inhibitor
| CAS | 2055397-28-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H13F2N3O3S |
| Formula Weight | 389.38 |
810
Tocris Bioscience™ SB 431542
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Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| CAS | 301836-41-9 |
|---|---|
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C22H16N4O3 |
| Formula Weight | 384.39 |