Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Molecular Weight (g/mol)
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1,291
R&D Systems™ DCEBIO
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Activates Cl- conductance and hKCa3.1 channels
| CAS | 60563-36-2 |
|---|---|
| Solubility | Soluble to 100mM in DMSO |
| Chemical Name or Material | 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C9H8Cl2N2O |
| Formula Weight | Observed MW: 231.08 |
| Assay Percent Range | >99% |
1,292
R&D Systems™ MS 275
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. HDAC (Class I) inhibitor
| CAS | 209783-80-2 |
|---|---|
| Chemical Name or Material | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N4O3 |
| Formula Weight | Observed MW: 376.41 |
| Assay Percent Range | >99% |
1,293
R&D Systems™ TBB
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 17374-26-4 Molecular Formula: C6HBr4N3
| CAS | 17374-26-4 |
|---|---|
| Molecular Formula | C6HBr4N3 |
1,294
R&D Systems™ CHR 6494 trifluoroacetate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective haspin inhibitor
1,295
R&D Systems™ Dynole 34-2
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1128165-88-7 Molecular Formula: C25H36N4O
| CAS | 1128165-88-7 |
|---|---|
| Molecular Formula | C25H36N4O |
1,296
R&D Systems™ ABT 199
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective, high affinity Bcl-2 inhibitor; orally bioavailable
| Target | Bcl-2 Family Inhibitors |
|---|---|
| CAS | 1257044-40-8 |
| Product Type | Inhibitor |
| Purity | 98% |
| Chemical Name or Material | 4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2 H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1 H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide |
| Recommended Storage | Store at -20°C |
| Synonym | GDC-0199 |
| Molecular Formula | C45H50ClN7O7S |
| Formula Weight | 868.45 |
1,297
R&D Systems™ VX 745
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 209410-46-8 Molecular Formula: C19H9Cl2F2N3OS
| CAS | 209410-46-8 |
|---|---|
| Molecular Formula | C19H9Cl2F2N3OS |
1,298
R&D Systems™ PF 06465469
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1407966-77-1 Molecular Formula: C30H33N7O2
| CAS | 1407966-77-1 |
|---|---|
| Molecular Formula | C30H33N7O2 |
1,299
R&D Systems™ SIS3
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
| Product Type | SIS3 |
|---|---|
| Molecular Weight (g/mol) | 489.99 |
| Purity | 97% |
1,300
R&D Systems™ Blasticidin S HCl
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A Tocris product, part of R&D Systems. Antibiotic; selection reagent for bis, bsr and BSD transformed cells
1,301
R&D Systems™ NPE-caged-proton
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1186195-63-0 Molecular Formula: C8H8NNaO6S
| CAS | 1186195-63-0 |
|---|---|
| Molecular Formula | C8H8NNaO6S |
1,302
R&D Systems™ LY 487379 hydrochloride
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CAS: 353229-59-1 Molecular Formula: C21H20ClF3N2O4S
| CAS | 353229-59-1 |
|---|---|
| Molecular Formula | C21H20ClF3N2O4S |
1,303
R&D Systems™ Trametinib
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A Tocris product, part of R&D Systems. Potent and selective MEK inhibitor; orally bioavailable
| Target | MEK Inhibitors |
|---|---|
| CAS | 871700-17-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H23FIN5O4 |
1,304
R&D Systems™ PHTPP
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CAS: 805239-56-9 Molecular Formula: C20H11F6N3O
| CAS | 805239-56-9 |
|---|---|
| Molecular Formula | C20H11F6N3O |
1,305
R&D Systems™ Ciclopirox
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A Tocris product, part of R&D Systems. Pan-histone demethylase inhibitor
| CAS | 29342-05-0 |
|---|---|
| Chemical Name or Material | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C12H17NO2 |
| Formula Weight | Observed MW: 207.27 |
| Assay Percent Range | >99% |