Crosslinking Reagents
Sigma Aldrich Fine Chemicals Biosciences Dimethyl pimelimidate dihydrochloride | 58537-94-3 | MFCD00038942 | 1g
Dimethyl pimelimidate dihydrochloride | 259.17 | 58537-94-3 | MFCD00038942 | 1g
Cayman Chemical CInabarInIc AcId 50mg
An agonist of mGluR4 and active metabolite of 3-hydroxyanthranilic acid; selectively induces inositol phosphate production in HEK293 cells expressing mGluR4 over HEK293 cells expressing mGluR1, mGluR2, mGluR5, mGluR6, mGluR7, or mGluR8 at 100 µM; inhibits DAAO in a cell-free assay (IC50 = 1.37 µM); increases levels of ROS and induces apoptosis in primary mouse thymocytes at 30 µM
Cayman Chemical RItalInIc AcId 50mg
An inactive, major metabolite of methylphenidate; intended for forensic and biological research purposes
Perkin Elmer US LLC SPB Probe 6 in. for 50 mL Tubes
The SPB Probe provides direct control and monitoring of actual sample temperature via a corrosion-resistant, PFA-coated temperature probe. Each probe is supplied with five Probe Watch Glasses and a probe holder.
Cayman Chemical AmIno TadalafIl 50mg
An analog of tadalafil that has been detected as an illegal adulterant in a dietary supplement
Cayman Chemical 1 3 7-TrImethylurIc AcId 50mg
A metabolite of caffeine; scavenges hydroxyl radicals in a cell-free assay at 500 µM; inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes
Diagenode Inc ChIP Cross-link Gold, 250x concentrated solution, 600 μL
The Diagenode ChIP Cross-link Gold (C01019027) is a specialized reagent that enhances chromatin immunoprecipitation (ChIP) assays by stabilizing protein-protein interactions. This innovative product addresses the limitations of traditional formaldehyde fixation, particularly for proteins not directly bound to DNA. It facilitates a sequential fixation protocol that stabilizes protein complexes before interlinking protein-DNA, yielding a more comprehensive view of chromatin architecture.
- Application in chromatin immunoprecipitation (ChIP)
- Enhances protein-protein cross-linking
- Targets higher-order and dynamic protein interactions
- Shipped at -20°C
- Store at -20°C; for long term, store at -80°C
- Volume of 600 μL
- Avoid multiple freeze-thaw cycles
- 250x concentrated solution
Medchemexpress LLC Lys-SMCC-DM1 | 1281816-04-3 | 98.2% | 1103.71 g/mol | C53H75ClN6O15S | 1 MG
Lys-SMCC-DM1 is a lysine-conjugated SMCC-DM1 linker-payload metabolite used in antibody-drug conjugate (ADC) research. It serves as the active metabolite of the DM1 payload and is used as a linker-payload building block and analytical reference for ADC development, characterization, and stability studies. Molecular formula C53H75ClN6O15S; molecular weight 1103.71 g/mol. Store under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Used as an ADC linker-payload building block and analytical reference.
- Active DM1 metabolite that contributes to tubulin inhibition assays.
- Purified small molecule suitable for conjugation workflows.
- Stable under specified cold-storage conditions when stored under nitrogen.
- Molecular characterization supports analytical method development.
Cell Signaling Technology Human Reactive Inflammatory Cytokine Antibody Sampler Kit 1 Kit
Human Reactive Inflammatory Cytokine Antibody Sampler Kit 1 Kit
Cayman Chemical QuIlaIc AcId 50mg
A triterpene saponin with diverse biological activities; cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively); induces hot plate analgesia in mice (ED50 = 20.7 mg/kg); reduces arachidonic acid- or TPA-induced EAr edema in mice when administered at 0.7 and 1.6 mg/ear, respectively
![eMolecules Sulfo-SMCC | Combi-Blocks, Inc. | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 5g | 589787848](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2082641.JPG-250.jpg)
eMolecules Sulfo-SMCC | Combi-Blocks, Inc. | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 5g | 589787848
Sulfo-SMCC | Combi-Blocks, Inc. | 92921-24-9 | MFCD00054978 | 436.370 | C16H17N2NaO9S | 95.000 | [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O | 5g | 589787848
Cayman Chemical GlycohyodeoxycholIc AcId 50mg
A major metabolite of hyodeoxycholic acid in humans; supplementation in prairie dogs fed a lithogenic diet decreases the frequency of cholesterol crystals in the gallbladder; inhibits the activity of cholesterol 7α-hydroxylase
Cayman Chemical OrselInIc AcId 50mg
A fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities; scavenges DPPH radicals (IC50 = 5 mM); prevents PAF-induced PARP cleavage in PC12-AC cells and PAF-induced cytotoxicity in Pafr-/-mouse cerebellar granule cells at 1 μg/ml
Cayman Chemical Clobetasol PropIonate 1g
A corticosteroid; binds to glucocorticoid receptors in a cell-free assay (IC50 = 3.17 nM) and inhibits proliferation of primary human skin fibroblasts at 5 UG/ml; topical administration reduces croton oil-induced EAr edema in mice
eMolecules TargetMol DSG Crosslinker 200mg 726061666 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
TargetMol DSG Crosslinker 200mg 726061666 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8