Protein Modification Reagents
eMolecules Biotin-PEG8-amine | 2183447-27-8 | | 500mg
Broadpharm | Biotin-PEG8-amine | 500mg | 550804573 | BP-24267 | | 2183447-27-8 | | 638.820 | C28H54N4O10S
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Medchemexpress LLC DSPE-PEG-DBCO sodium | 2052955-83-4 | 95.0% | 5000 (average) | 1 MG
DSPE-PEG-DBCO sodium (MW 5000) is a PEGylated phospholipid that combines a DSPE lipid anchor with a dibenzocyclooctyne (DBCO) reactive handle, designed for incorporation into lipid formulations and for strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation in drug delivery research.
- Pegylated lipid with DBCO functionality for copper-free click chemistry.
- Sodium salt form supplied as a white to yellow solid.
- Average molecular weight approximately 5000 daltons.
- Purity approximately 95% by supplier analysis.
- Enables liposome and nanoparticle surface functionalization.
- Store at -20°C and protect from light; follow solvent storage guidance for long-term stability.
eMolecules M-PEG3-CH2COOH | 16024-60-5 | MFCD25959645 | 1g
AstaTech | M-PEG3-CH2COOH | 1g | 386071048 | W13676 | 95.000 | 16024-60-5 | MFCD25959645 | 222.237 | C9H18O6
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Medchemexpress LLC DSPE-PEG-SH | 90.0% | 10 MG
DSPE-PEG-SH (MW 1000) is a thiol-terminated pegylated phospholipid consisting of a DSPE hydrophobic anchor and a polyethylene glycol chain with an average molecular weight of 1000. It self-assembles into lipid bilayers and is commonly used to functionalize liposomes and lipid nanoparticles. The terminal thiol enables site-specific conjugation for attaching ligands, peptides, or probes, while the PEG chain imparts steric stabilization and improved circulation properties.
- Thiol terminal for site-specific conjugation.
- DSPE anchor for stable membrane incorporation.
- Pegylated chain for steric stabilization and reduced opsonization.
- Average molecular weight 1000 for short PEG spacer properties.
- Suitable for liposome and lipid nanoparticle functionalization.
Medchemexpress LLC Mal-PEG2-oxyamine | 1146245-73-9 | 95.0% | C10H16N2O5 | 10MG
Mal-PEG2-oxyamine is a bifunctional PEG-based linker for use in the synthesis of PROTACs. It features a maleimide group and an aminooxy (oxyamine) group connected by a short PEG2 spacer, permitting orthogonal conjugation to thiol and carbonyl functionalities for targeted protein degradation research. The product is supplied with a reported purity of 95% and includes storage and solubility guidance for research applications.
- Bifunctional maleimide and aminooxy reactive groups.
- PEG2 spacer provides a short, flexible linkage.
- Enables selective conjugation to thiol and carbonyl partners.
- Reported purity supports synthetic and analytical use.
- Includes storage and solubility recommendations for stability.
eMolecules NH2-PEG3-COOH | AstaTech | 784105-33-5 | MFCD21607085 | 221.253 | C9H19NO5 | 95.000 | NCCOCCOCCOCCC(O)=O | 1g | 384830647
NH2-PEG3-COOH | AstaTech | 784105-33-5 | MFCD21607085 | 221.253 | C9H19NO5 | 95.000 | NCCOCCOCCOCCC(O)=O | 1g | 384830647
Cayman Chemical PAMAM Dendrimer G2 0 Amine w
An amine-terminated PAMAM dendrimer; ~29 Å in diameter; has 16 surface groups; enhances the solubility and antibacterial activity of erythromycin against S. aureus when administered in combination with erythromycin at 15 mg/ml; increases the cell growth rate of HEK293T and HeLa cells from 100-500 nM but is cytotoxic to the same cells at ≥700 nM; enhances the nasal absorption of fluorescein isothiocyanate-labeled dextran in rats when administered in combination
![eMolecules Broadpharm / TAMRA-PEG4-Methyltetrazine / 1mg / 268505117 / BP-22443 / 90.000 / 2163772-19-6 / [null] / 775.863 / C42H45N7O8](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465468.JPG-250.jpg)
eMolecules Broadpharm / TAMRA-PEG4-Methyltetrazine / 1mg / 268505117 / BP-22443 / 90.000 / 2163772-19-6 / [null] / 775.863 / C42H45N7O8
Broadpharm / TAMRA-PEG4-Methyltetrazine / 1mg / 268505117 / BP-22443 / 90.000 / 2163772-19-6 / [null] / 775.863 / C42H45N7O8
eMolecules Azide-PEG3-Tos | 178685-33-1 | MFCD18433411 | 1g
Broadpharm | Azide-PEG3-Tos | 1g | 282987813 | BP-22769 | 98.000 | 178685-33-1 | MFCD18433411 | 329.370 | C13H19N3O5S
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Medchemexpress LLC DSPE-PEG-DBCO | 99.9% | 2000 (average) | 25 MG
DSPE-PEG-DBCO (MW 2000) is a PEGylated phospholipid conjugate bearing a dibenzocyclooctyne (DBCO) group. It serves as a click-chemistry-capable lipid for incorporation into lipid nanoparticles or micelles and for rapid, copper-free conjugation to azide-containing molecules via strain-promoted alkyne-azide cycloaddition (SPAAC). Typical uses include nanoparticle formulation, surface PEGylation, and bioconjugation.
- PEGylated phospholipid with average molecular weight 2000.
- DBCO functional group enables copper-free SPAAC with azides.
- Suitable for lipid nanoparticle and micelle formulation.
- Facilitates bioconjugation and surface modification.
- High purity (reported 99.9%) for research applications.
Medchemexpress LLC Biotin-PEG2-C6-azide 50mg | 1011268-29-3 | 50 MG
Biotin-PEG2-C6-azide is a biotinylated PEG-based linker (CAS 1011268-29-3) containing an azide functional group used primarily in click chemistry and linker synthesis. It is supplied as a research reagent for conjugation, affinity capture, and PROTAC development.
- Contains a biotin tag for selective affinity capture of conjugates.
- Azide functional group enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- PEG2 spacer improves solubility and provides flexible linkage between groups.
- Appropriate for PROTAC linker synthesis, bioconjugation, and pull-down assays.
- Provided in small laboratory pack sizes suitable for research use.
![Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl) pentaoxa-4-azanonadecan-oate | 00-00-0 | 95.0% | C26H38N2O10 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259060.png-250.jpg)
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl) pentaoxa-4-azanonadecan-oate | 00-00-0 | 95.0% | C26H38N2O10 | 10MG
BCN-PEG4-NHS ester is a polyethylene glycol-based bifunctional linker that pairs a bicyclononyne moiety for copper-free click conjugation with an N-hydroxysuccinimide activated ester for amine coupling. Supplied as a colorless to light yellow liquid with high reported purity, it is designed for bioconjugation, linker assembly, and synthesis workflows that require efficient, selective coupling and good solubility.
- enables copper-free click conjugation via strain-promoted alkyne-azide cycloaddition.
- provides an NHS-activated ester for rapid amine coupling.
- peg4 spacer enhances solubility and reduces steric hindrance.
- high reported purity suitable for synthetic and bioconjugation use.
- stable under recommended frozen storage for extended shelf life.
- available in small pack sizes for method development and optimization.
Medchemexpress LLC Propargyl-PEG4-NHS ester | 1428629-70-2 | MFCD22380743 | 97.0% | 357.36 g/mol | C16H23NO8 | 250 MG
Propargyl-PEG4-NHS ester is a noncleavable four-unit polyethylene glycol (PEG) linker bearing a propargyl (alkyne) group and an N-hydroxysuccinimide (NHS) ester. It is used as a click chemistry reagent to couple azide-containing molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC), and as a PEG-based linker in antibody-drug conjugate synthesis and other bioconjugation applications.
- Noncleavable four-unit PEG linker provides a hydrophilic spacer.
- Terminal propargyl (alkyne) group enables copper-catalyzed azide-alkyne click chemistry.
- NHS ester is amine-reactive for efficient conjugation to primary amines.
- High purity (97.0%) and molecular weight of 357.36 g/mol aid predictable performance.
- Viscous liquid form; recommended storage: pure form -20°C, in solvent -80°C or -20°C.