Protein Modification Reagents
Medchemexpress LLC t-Boc-N-amido-PEG5-acetic acid | 890152-41-7 | MFCD31656900 | 98.0% | 395.45 | C17H33NO9 | 1 G
t-Boc-N-amido-PEG5-acetic acid is a Boc-protected PEG-based linker used for assembling PROTACs and other bioconjugates. It provides a flexible, hydrophilic spacer with a terminal acetic acid and a Boc-protected amine, enabling standard coupling and selective deprotection steps during synthesis.
- Provides a five-unit polyethylene glycol spacer for flexible linkage.
- Contains a terminal acetic acid for straightforward conjugation chemistry.
- Features a Boc-protected amine to allow selective deprotection and functionalization.
- Suitable for synthesis of heterobifunctional degraders and bioconjugates.
- Available in multiple pack sizes for research-scale synthesis.
Medchemexpress LLC Biotin-PEG4-hydrazide | 756525-97-0 | 99.9% | C21H39N5O7S | 25 MG
Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker. It is used in the synthesis of Proteolysis-targeting chimeras (PROTACs), which exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC m-PEG-DMG | 5,000 Da (average) | 10 MG
m-PEG-DMG (MW 5000) is a methoxy-terminated polyethylene glycol (PEG) conjugated to a dimyristoyl glycerol (DMG) lipid tail used as a PEG-lipid component in lipid nanoparticle and drug delivery formulations. It provides steric stabilization and can improve the delivery efficiency and tissue specificity of poorly soluble drugs.
- Used as a PEG-lipid in lipid nanoparticles and drug delivery research.
- Average molecular weight about 5,000 Da.
- Typically supplied as a powder with recommended storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Solubility in DMSO approximately 50 mg/mL (ultrasonic assistance may be required).
- Provides steric stabilization to nanoparticle surfaces and can reduce aggregation and opsonization.
Worthington Biochemical Corporation COLLAGENASE 4KU CLSPA
Chromatographically purified. <50 caseinase units per milligram. Supplied as a lyophilized powder.
Medchemexpress LLC Biotin-PEG4-NHS ester | 459426-22-3 | 99.6% | C25H40N4O10S | 250 MG
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It is designed for use in the synthesis of PROTACs, which are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled compound
- PEG-based linker
- Used for PROTAC synthesis
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules Fmoc-PEG4-NHS ester | 1314378-14-7 | MFCD20227659 | 1g
Broadpharm | Fmoc-PEG4-NHS ester | 1g | 229582925 | BP-20644 | 98.000 | 1314378-14-7 | MFCD20227659 | 584.622 | C30H36N2O10
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Nanocs Vitamin B12 PEG Biotin, 5000 Da, 5 mg
Vitamin B12 PEG Biotin is one of Nanocs bioactive PEG derivatives that can be used for bioassay development. Vitamin B12, also known as cobalamin or cyanocobalamin, is a water soluble vitamin that is involved in the metabolism of cells in human body. Product Specifications:Form: Solid powderColor: RedSolubility: Soluble in waterFunctional ligand: biotinBinding target: Avidin, streptavidin or neutravidinApplications: Bioassay development
Medchemexpress LLC Mal-amido-PEG12-NHS ester | 2101722-60-3 | 98.52% | C38H63N3O19 | 25 MG
Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC TCO-PEG3-Biotin | 99.9% | 570.74 g/mol | C27H46N4O7S | 10 MG
TCO-PEG3-Biotin is a cleavable three-unit PEG linker used for antibody-drug conjugate (ADC) synthesis and click-chemistry bioconjugation. It contains a trans-cyclooctene (TCO) moiety that reacts with tetrazine-functionalized partners via inverse electron-demand Diels-Alder (iEDDA) chemistry. This product is for research use only.
- Cleavable three-unit PEG linker suitable for ADC synthesis.
- Enables rapid iEDDA click chemistry with tetrazine-functionalized molecules.
- High purity: 99.9%.
- Molecular weight: 570.74 g/mol.
- Chemical formula: C27H46N4O7S.
- Appearance: white to off-white solid.
- Storage: powder at -20°C; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
- Available quantity: 10 MG.