Protein Modification Reagents
Medchemexpress LLC Tco-peg8-nhs ester | 2353409-95-5 | 95.0% | C32H54N2O14 | 10MG
TCO-PEG8-NHS ester is a PEG-based PROTAC linker with an N-hydroxysuccinimide (NHS) activated ester that enables efficient conjugation to primary amines. The molecule incorporates a trans-cyclooctene (TCO) moiety separated by an eight-unit PEG spacer to provide aqueous solubility and flexible spacing for bioconjugation and targeted protein degradation construct synthesis.
- NHS-activated ester for efficient amide bond formation.
- Eight-unit PEG spacer improves solubility and flexibility.
- Provides a trans-cyclooctene (TCO) handle for click chemistry.
- High reported purity (95.0%).
- Supplied in small-mass packages suitable for research use.
![eMolecules endo-BCN-PEG4-acid | Broadpharm | 2226472-38-2 | MFCD23704190 | 441.521 | C22H35NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 204725189](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1763703.jpg-250.jpg)
eMolecules endo-BCN-PEG4-acid | Broadpharm | 2226472-38-2 | MFCD23704190 | 441.521 | C22H35NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 204725189
endo-BCN-PEG4-acid | Broadpharm | 2226472-38-2 | MFCD23704190 | 441.521 | C22H35NO8 | 0.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 204725189
Medchemexpress LLC Azide-PEG5-Tos | 236754-49-7 | MFCD28505520 | 98.5% | 417.48 g/mol | C17H27N3O7S | 250 MG
Azide-PEG5-Tos is a cleavable five-unit polyethylene glycol (PEG5) linker bearing an azide functional group and a tosyl leaving group. It is used as a click-chemistry compatible linker and crosslinker for antibody-drug conjugates (ADCs) and other bioconjugation applications.
- Cleavable five-unit PEG linker suitable for ADC synthesis.
- Azide functional group enables CuAAC and strain-promoted cycloaddition.
- High purity suitable for research applications.
- Soluble in DMSO at ≥100 mg/mL.
- Molecular weight 417.48 g/mol; chemical formula C17H27N3O7S.
- Available in milligram to gram pack sizes, including 250 MG.
eMolecules Broadpharm / Mal-amido-PEG5-NHS / 100mg / 795361687 / BP-40158 / / 1315355-92-0 / MFCD20230002 / 557.553 / C24H35N3O12
Broadpharm / Mal-amido-PEG5-NHS / 100mg / 795361687 / BP-40158 / / 1315355-92-0 / MFCD20230002 / 557.553 / C24H35N3O12
eMolecules Mal-PEG2-Val-Cit-PAB-OH | 2055041-38-6 | MFCD29918233 | 50mg
Broadpharm | Mal-PEG2-Val-Cit-PAB-OH | 50mg | 368397818 | BP-23203 | 98.000 | 2055041-38-6 | MFCD29918233 | 618.688 | C29H42N6O9
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eMolecules Cbz-N-amido-PEG15-amine | | MFCD30723279 | 1g
Broadpharm | Cbz-N-amido-PEG15-amine | 1g | 340376868 | BP-23502 | 98.000 | | MFCD30723279 | 855.029 | C40H74N2O17
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Medchemexpress LLC Mal-amido-PEG5-C2-NHS ester | 1315355-92-0 | ≥98.0% | 557.55 g·mol⁻1 | C24H35N3O12 | 100 MG
Mal-amido-PEG5-C2-NHS ester is a noncleavable linker reagent combining a maleimide and an N-hydroxysuccinimide (NHS) ester for thiol- and amine-directed bioconjugation. It is intended for labeling primary amines and for constructing stable linkages in antibody-drug conjugates, protein, and oligonucleotide conjugations.
- Contains maleimide for thiol-selective conjugation
- Contains NHS ester reactive toward primary amines
- High purity (≥98.0%) suitable for research use
- Molecular weight ~557.55 and formula C24H35N3O12
- Available in a 100 mg package for lab-scale synthesis and labeling workflows
Medchemexpress LLC M-PEG15-NHS ester | 00-00-0 | 98.0% | C39H73NO20 | 10MG
m-PEG15-NHS ester is a methoxy-terminated polyethylene glycol (PEG) N-hydroxysuccinimide ester used as a hydrophilic linker in PROTAC synthesis and bioconjugation. It supplies an amine-reactive NHS group for covalent coupling to primary amines and a PEG15 spacer to improve solubility, flexibility, and distance between conjugated moieties.
- Provides an NHS ester for efficient amine coupling.
- Contains a methoxy-terminated PEG15 spacer to increase solubility.
- High purity (98.0%) suitable for research applications.
- Storage recommended at -20°C, sealed and protected from moisture and light.
- Available in multiple package sizes to support different scales of synthesis.
eMolecules Broadpharm / Biotin-PEG4-Picolyl azide / 5mg / 296213266 / BP-22954 / 95.000 / 2222687-71-8 / MFCD29052186 / 622.740 / C27H42N8O7S
Broadpharm / Biotin-PEG4-Picolyl azide / 5mg / 296213266 / BP-22954 / 95.000 / 2222687-71-8 / MFCD29052186 / 622.740 / C27H42N8O7S
Medchemexpress LLC N3-PEG3-VC-PAB-MMAF | 2757277-32-8 | 100.0% | 1352.62 g/mol | C66H105N13O17 | 10 MG
N3-PEG3-VC-PAB-MMAF is an azide-functional drug-linker conjugate used for antibody-drug conjugate (ADC) research and bioconjugation. It combines a PEG3-VC-PAB cleavable linker with the tubulin inhibitor MMAF, and is designed for click-chemistry attachment to alkyne or strained-alkyne partners.
- Enables click chemistry conjugation via azide handle.
- Contains a cleavable valine-citrulline-PAB linker for payload release.
- Suitable for ADC linker-payload synthesis and site-specific attachment.
- Solid, white to off-white material with high purity for research use.
Chemscene ChemScene | DL-dithiothreitol | 500G | CS-3035 | 0.98 | 578517| MFCD00004877 | 154.25
ChemScene | DL-dithiothreitol | 500G | CS-3035 | 0.98 | 578517| MFCD00004877 | 154.25
Crescent Chemical Co Inc MERCAPTOETHANOL MOL BIO GRADE
Mercaptoethanol molecular biology grade DNase/RNase not detected. Size - 50ML Storage Conditions - +2 °C TO +8 °C Catalog Number - 39563.01 CAS 60-24-2