Protein Modification Reagents
eMolecules Biotin-PEG4-alcohol | 1217609-84-1 | MFCD03701139 | 1g
Broadpharm | Biotin-PEG4-alcohol | 1g | 309209152 | BP-20650 | 98.000 | 1217609-84-1 | MFCD03701139 | 419.540 | C18H33N3O6S
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Medchemexpress LLC BODIPY FL alkyne | 1MG
BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex 503 nm Em 512 nm) a bright and photostable fluorophore which emits in fluorescein (FAM) channel BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry
Medchemexpress LLC Mal-PEG5-NHS ester | 1807537-42-3 | 99.04% | 25 MG
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Alkyl/ether and PEG-based PROTAC linker
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Contains two different ligands connected by a linker
Medchemexpress LLC DSPE-Thiol | 144735-82-0 | MFCD29079392 | 90.0% | 836.19 g·mol⁻¹ | C44H86NO9PS | 5 MG
A thiol-capped distearoyl phosphatidylethanolamine (DSPE) phospholipid for thiol-based conjugation and lipid surface modification. The terminal thiol selectively reacts with maleimide and other thiol-reactive groups, enabling preparation of phospholipid dimers, surface functionalization of liposomes or lipid nanoparticles, and formation of stable thiol-linked conjugates. Supplied as a solid with reported solubility information for DMF and typical purity at 90.0%.
- Thiol-functionalized head group for selective thiol-maleimide conjugation.
- Suitable for liposome surface modification and nanoparticle functionalization.
- Enables preparation of phospholipid dimers and thiol-linked conjugates.
- Soluble in DMF with sonication and gentle heating to aid dissolution.
- Typical purity 90.0% and molecular weight 836.19 g·mol⁻¹.
Medchemexpress LLC Mal-amido-PEG2-TFP ester | 1431291-44-9 | 98.7% | 250 MG
Mal-amido-PEG2-TFP ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This product is for research use only.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs exploit the intracellular ubiquitin-proteasome system
- PROTACs selectively degrade target proteins
Medchemexpress LLC DBCO-PEG4-PFP ester | 00-00-0 | 95.0% | C36H35F5N2O8 | 10MG
DBCO-PEG4-PFP ester is a PEG-based linker and click-chemistry reagent used for bioconjugation and PROTAC linker construction. It combines a dibenzocyclooctyne (DBCO) group for strain-promoted alkyne-azide cycloaddition (SPAAC) with a pentafluorophenyl (PFP) ester reactive handle for coupling to nucleophiles such as amines.
- Enables copper-free click reactions with azide-functionalized partners.
- Provides an active pentafluorophenyl ester for efficient amide bond formation with amines.
- Includes a PEG4 spacer to improve solubility and reduce steric hindrance.
- Suitable for PROTAC linker synthesis and general bioconjugation workflows.
- High purity and recommended storage support reproducible laboratory results.
Cayman Chemical VH 032 LInker 1 25mg
A PROTAC precursor; has been used in the synthesis of PROTACs targeting TEAD in cancer cells
STA PHARMACEUTICAL US LLC Fmoc-N-amido-PEG-9-COOH | 100 g | CAS 1191064-81-9 | MDL MFCD28385470
Fmoc-N-amido-PEG-9-COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1191064-81-9
- MDL: MFCD28385470
- InChIKey: NEESTRVILHNOJT-UHFFFAOYSA-N
- Molecular Weight: 707.814
- Molecular Formula: C36H53NO13
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Folic acid-PEG5-Mal | 00-00-0 | 99.5% | C35H45N9O12 | 10MG
FA-PEG5-Mal is a polyethylene glycol (PEG)-based linker developed for constructing proteolysis-targeting chimeras (PROTACs). It combines a folic acid-derived ligand with a PEG5 spacer and a maleimide functional group to enable selective conjugation to thiol-containing partners. Supplied as a solid for laboratory research use, it offers high purity and convenient solubility in DMSO for bioconjugation and linker assembly workflows.
- Provides a folic acid ligand for target engagement
- Contains a PEG5 spacer to give flexible linker length
- Includes a maleimide functional handle for thiol coupling
- Supplied as a solid suitable for laboratory research use
- High purity for reliable synthetic results
- Soluble in DMSO (100 mg/mL) with ultrasonic assistance recommended
Medchemexpress LLC Biotin-PEG4-amide-alkyne | 1006592-45-5 | MFCD16621136 | 95.0% | C24H40N4O7S | 10MG
Biotin-PEG4-amide-alkyne is a polyethylene glycol (PEG)-based linker reagent that combines a biotin affinity tag with a terminal alkyne group for click chemistry applications. Supplied as an off-white to light yellow solid (CAS 1006592-45-5), it is designed for bioconjugation, affinity capture, and incorporation into PROTAC and probe chemistries.
- Contains a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Includes a biotin moiety for strong affinity capture and detection.
- Features a PEG4 spacer to enhance aqueous solubility and reduce steric hindrance.
- Supplied as a stable solid suitable for storage and handling in research labs.
- Applicable to bioconjugation, probe synthesis, and PROTAC linker construction.
Medchemexpress LLC Peg4-aminooxy-MMAF | 1415246-35-3 | 923.19 | C47H82N6O12 | 50 MG
PEG4-aminooxy-MMAF is a drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It links the antitubulin payload MMAF to a noncleavable PEG4 spacer terminated with an aminooxy functional group, enabling oxime-based conjugation to aldehyde- or ketone-containing antibodies or linkers.
- Drug-linker conjugate for ADC research.
- Contains an aminooxy-terminated PEG4 spacer for oxime conjugation.
- MMAF payload provides potent antitubulin activity.
- Molecular weight 923.19.
- Chemical formula C47H82N6O12.
- Available in small research pack sizes, including 50 mg.
eMolecules t-Boc-N-amido-PEG4-NHS ester | Broadpharm | 859230-20-9 | MFCD20228887 | 462.496 | C20H34N2O10 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 1g | 340377001
t-Boc-N-amido-PEG4-NHS ester | Broadpharm | 859230-20-9 | MFCD20228887 | 462.496 | C20H34N2O10 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 1g | 340377001
eMolecules AstaTech / AZIDO-PEG3-ALDEHYDE / 0.25g / 570586065 / D84646 / 95.000 / 1807530-10-4 / MFCD28976706 / 231.252 / C9H17N3O4
AstaTech / AZIDO-PEG3-ALDEHYDE / 0.25g / 570586065 / D84646 / 95.000 / 1807530-10-4 / MFCD28976706 / 231.252 / C9H17N3O4
eMolecules Tri(Amino-PEG5-amide)-amine | 2055013-52-8 | MFCD28142444 | 500mg
Broadpharm | Tri(Amino-PEG5-amide)-amine | 500mg | 393649485 | BP-22369 | | 2055013-52-8 | MFCD28142444 | 1020.270 | C45H93N7O18
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