Protein Modification Reagents
Medchemexpress LLC Azido-PEG20-alcohol | 1637297-21-2 | >98% | C40H81N3O20 | 100 MG
Azido-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC Methoxy-polyethylene glycol-distearoylphosphatidylethanolamine sodium salt | 95.0% | 3,000 Da (average) | 250 MG
m-PEG-DSPE sodium (MW 3000) is a methoxy-polyethylene glycol-conjugated distearoylphosphatidylethanolamine supplied as the sodium salt for research use. It is used as a PEG lipid in nanoparticle and micelle formulations to extend circulation time, improve colloidal stability, and reduce protein adsorption in colloidal drug-delivery systems.
- PEGylated phospholipid sodium salt for surface modification.
- Average molecular weight ~3,000 Da reflecting PEG chain length.
- Purity approximately 95.0% as specified by the manufacturer.
- Suitable for formulation of liposomes, lipid nanoparticles, and micelles.
- Improves circulation time and reduces opsonization.
- Supplied as a small-scale research package for laboratory use.
Medchemexpress LLC Cholesterol-PEG-maleimide | 95.1% | 2000 Da (average) | 10 MG
Cholesterol-PEG-maleimide (average MW 2000) is a cholesterol-terminated polyethylene glycol conjugate bearing a maleimide reactive group. It self-assembles in aqueous media and is used to modify liposomes or nanoparticles and to covalently attach thiol-containing ligands via maleimide-thiol chemistry.
- Maleimide functional group reacts selectively with thiol groups to form stable thioether bonds.
- Cholesterol terminus anchors into lipid bilayers for stable surface modification.
- PEG (average MW 2000) provides steric stabilization and improved circulation time.
- Amphiphilic structure facilitates liposome and nanoparticle formulation.
- Available in small research pack sizes suitable for formulation and conjugation studies.
Medchemexpress LLC DSPE-PEG-DBCO sodium | 99.6% | 3400 (average) | 5 MG
DSPE-PEG-DBCO sodium (MW 3400) is a DBCO-functionalized PEGylated phospholipid supplied as a white to off-white solid. It provides a bioorthogonal DBCO handle for strain-promoted azide-alkyne cycloaddition (SPAAC) and an amphiphilic DSPE-PEG backbone suitable for incorporation into liposomes and lipid nanoparticles for surface functionalization and delivery research.
- Provides DBCO handle for copper-free click conjugation.
- Enables surface functionalization of liposomes and nanoparticles.
- Amphiphilic PEG-lipid backbone supports stable lipid formulations.
- PEG chain (average MW 3400) imparts steric stabilization and solubility.
- Supplied as a solid suitable for small-scale research use.
- Available in small packaged quantities for laboratory experiments.
Cayman Chemical PEG 2000-dPE 50mg
A PEGylated form of DSPE; has been used in the generation of micelles and in combination with other lipids in the formation of liposomes; liposomes containing DSPE-mPEG(2000) and encapsulating doxorubicin and quercetin reduce tumor growth in an MCF-7/adr multidrug-resistant breast cancer mouse xenograft model
Medchemexpress LLC 2-((1E,3Z)-3-(1-(1-((E)-Cyclooct-2-en-1-yloxy)-1,12-dioxo-5,8-dioxa-2,11-diazaheptadecan-17-yl)-3,3- | 91.1% | 775.46 | C45H63ClN4O5 | 10 MG
Cy3-PEG2-TCO is a Cy3-based fluorescent reagent containing a two-unit PEG spacer and a trans-cyclooctene (TCO) functional group. It is designed for rapid bioorthogonal conjugation via inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine-bearing partners and is intended for research use in labeling, imaging, and bioconjugation workflows.
- Fluorescent Cy3 dye derivative suitable for imaging and labeling.
- PEG2 spacer improves solubility and reduces steric hindrance during conjugation.
- TCO functional group enables fast, selective iEDDA click reactions with tetrazines.
- Supplied as a solid with color ranging brown to reddish brown.
- High purity (~91.1%) with molecular weight 775.46 g·mol-1.
- Store protected from light under nitrogen at -20°C; in solvent, store at -80°C for long term.
Medchemexpress LLC m-PEG-DMG (MW 2000) | 1019000-64-6 | 98.0% | 2000 (average) | No fixed chemical formula - polymeric m-PEG-DMG (average MW 2000) | 10 MG
m-PEG-DMG (MW 2000) is a methoxy-terminated polyethylene glycol conjugated to dimyristoyl glycerol, provided as a solid PEGylated lipid for formulation research. It is used to prepare liposomes and lipid nanoparticles for drug delivery studies, and is supplied at an average molecular weight of 2000 with high purity for reliable experimental results.
- PEGylated lipid for liposome and lipid nanoparticle formulation.
- Average molecular weight 2000 for consistent PEG chain length.
- High purity (~98.0%) suitable for research applications.
- White to off-white solid, easy to handle in laboratory settings.
- Stable when stored as a powder at low temperatures for extended shelf life.
Medchemexpress LLC Dspe-peg-amine ammonium | 474922-26-4 | 99.5% | 1,000 g/mol (average) | (C2H4O)nN2O10P.NH3 | 250 MG
DSPE-PEG-Amine (average MW 1,000, ammonium salt) is a PEGylated phosphoethanolamine lipid bearing a terminal primary amine. It is formulated for incorporation into liposomes, micelles, and other nanoparticle systems to introduce reactive surface amines for covalent conjugation, targeting ligand attachment, and to provide steric stabilization in delivery research.
- Provides a primary amine terminus for bioconjugation.
- Incorporates into lipid bilayers and micelles for surface functionalization.
- Provides PEG steric stabilization to improve circulation and reduce aggregation.
- Suitable for covalent coupling to proteins, dyes, or targeting ligands.
- Average molecular weight 1,000 g/mol, polymeric PEG repeat unit.
- Recommend frozen, sealed storage and protection from moisture.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2COOH | 50 g | CAS 437655-96-4 | MDL MFCD26142983
Fmoc-NH-PEG6-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-96-4
- MDL: MFCD26142983
- InChIKey: HANLHKUCDRJGKX-UHFFFAOYSA-N
- Molecular Weight: 561.628
- Molecular Formula: C29H39NO10
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid
- SMILES: O=C(NCCOCCOCCOCCOCCOCCOCC(O)=O)OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
Medchemexpress LLC 4-Arm PEG-SCM MW 10 500mg
4-Arm PEG-SCM (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]