Protein Modification Reagents
Medchemexpress LLC Dspe-peg-cho | 89.0% | 2000 (Average) | 50 MG
DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent featuring DSPE phospholipids and aldehyde groups. Its PEG linkers provide good hydrophilicity and water solubility. This reagent is commonly used to bind antibodies, peptides, or other ligands to the surface of liposomes and lipid-polyethylene glycol nanoparticles.
- Linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups.
- PEG linkers provide good hydrophilicity and water solubility.
- Used to bind antibodies, peptides, or other ligands to liposomes and lipid-polyethylene glycol nanoparticles.
- Can be used for drug delivery.
Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-MMAE | 00-00-0 | 98.0% | C73H115N11O19 | 10MG
Mal-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It pairs a protease-cleavable Val-Cit-PAB peptide linker with the potent MMAE payload and a maleimide thiol-reactive handle, providing a reagent for thiol-based conjugation and intracellular, enzyme-triggered payload release.
![eMolecules Broadpharm / N-(Biotin-PEG2)-N-Bis(PEG3-azide) / 25mg / 761705491 / BP-28407 / 98.000 / / [null] / 776.950 / C32H60N10O10S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502474117.JPG-250.jpg)
eMolecules Broadpharm / N-(Biotin-PEG2)-N-Bis(PEG3-azide) / 25mg / 761705491 / BP-28407 / 98.000 / / [null] / 776.950 / C32H60N10O10S
Broadpharm / N-(Biotin-PEG2)-N-Bis(PEG3-azide) / 25mg / 761705491 / BP-28407 / 98.000 / / [null] / 776.950 / C32H60N10O10S
Medchemexpress LLC Ald-Ph-amido-PEG4-C2-NHS ester | 1353011-74-1 | 98.1% | 494.49 g/mol | C23H30N2O10 | 250 MG
A noncleavable 4-unit PEG linker bearing an NHS ester reactive group for antibody-agent conjugation. It is supplied for research use and is amine-reactive for coupling payloads to antibody lysines.
- Noncleavable 4-unit PEG spacer provides hydrophilicity and flexibility.
- NHS ester functionality for amine-reactive conjugation.
- High purity suitable for research applications.
- Soluble in DMSO; protocols provided for in vivo formulations.
- Stable when stored pure at -20°C.
Cayman Chemical VH 032 LInker 2 10mg
A VHL Ligand 1 derivative; comprises the VHL ligand domain and PEG linker of the BET inhibitor-containing PROTACs MZ2 and MZP-55
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 10 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
STA PHARMACEUTICAL US LLC Azide-PEG3-L-alanine-Fmoc | 50 g | CAS 2054345-69-4 | InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
Azide-PEG3-L-alanine-Fmoc is a Amino Acid reagent (Subcategory: Azido/Alkynyl AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2054345-69-4
- MDL: No data
- InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
- Molecular Weight: 484.509
- Molecular Formula: C24H28N4O7
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
- SMILES: O=C(N[C@H](COCCOCCOCCN=[N+]=[N-])C(O)=O)OCC1C2=C(C=CC=C2)C3=C1C=CC=C3
![eMolecules Broadpharm / TAMRA-PEG3-biotin / 1mg / 445408872 / BP-24274 / 97.000 / 2279944-59-9 / [null] / 831.000 / C43H54N6O9S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502496078.JPG-250.jpg)
eMolecules Broadpharm / TAMRA-PEG3-biotin / 1mg / 445408872 / BP-24274 / 97.000 / 2279944-59-9 / [null] / 831.000 / C43H54N6O9S
Broadpharm / TAMRA-PEG3-biotin / 1mg / 445408872 / BP-24274 / 97.000 / 2279944-59-9 / [null] / 831.000 / C43H54N6O9S
Cayman Chemical PomalIdomIde-d5 500ug
An internal standard for the quantification of pomalidomide by GC- or LC-MS
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 10 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Dbco-peg4-val-cit-pab-mmaf | 2244602-23-9 | 98.7% | 1672.01 | C88H126N12O20 | 50 MG
DBCO-PEG4-Val-Cit-PAB-MMAF is a cleavable antibody-drug conjugate (ADC) linker construct combining a DBCO click handle, a four-unit PEG spacer, a Val-Cit cleavable dipeptide, a PAB self-immolative spacer, and the cytotoxin MMAF. Supplied as a solid for conjugation workflows, it is intended for ADC synthesis and strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners.
- Cleavable Val-Cit linker for enzymatic payload release.
- DBCO handle enables copper-free click conjugation (SPAAC).
- PEG4 spacer improves solubility and reduces aggregation.
- High purity (~98.7%) suitable for research use.
- Supplied as a solid; recommended storage -20°C under nitrogen.
- Suitable for conjugation to azide-functionalized biomolecules.
Medchemexpress LLC Fluorescein-PEG4-acid | 1807518-76-8 | 96.3% | 654.68 | 50 MG
Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker.
Medchemexpress LLC Pomalidomide-PEG4-C2-NH2 | 2225940-52-1 | 95.11% | 492.52 | 2 G
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a 4-unit PEG linker used in PROTAC technology. It is for research use only and not sold to patients.
- Appearance: solid
- Color: light yellow to yellow
- Shipping: room temperature in continental US; may vary elsewhere.
- Storage: powder -20°C for 3 years, 4°C for 2 years. The compound is unstable in solutions, so freshly prepared solutions are recommended.
- Target: cereblon
- Related classifications: cancer, cancer targeted therapy, PROTAC E3 ligase ligand-linker conjugates.
- Usage: for research use only. We do not sell to patients.