Protein Modification Reagents
Cayman Chemical Boc-NH-PEG3-OH 100mg
A PEGylated building block; has been used as a spacer in biotinylated heterobifunctional cross-linker agents; has been used as a spacer in near infrared imaging probes for CYP1B1, which is expressed in a variety of tumors; has also been used in the synthesis of graftable peptidomimetics that bind to human αVβ3 integrin and inhibit adhesion of human osteoprogenitor cells to vitronectin
![eMolecules Biotin-PEG2-azide | Broadpharm | 945633-30-7 | MFCD26142991 | 400.500 | C16H28N6O4S | 98.000 | [N-]=[N+]=NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 250mg | 247403111](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1675450.jpg-250.jpg)
eMolecules Biotin-PEG2-azide | Broadpharm | 945633-30-7 | MFCD26142991 | 400.500 | C16H28N6O4S | 98.000 | [N-]=[N+]=NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 250mg | 247403111
Biotin-PEG2-azide | Broadpharm | 945633-30-7 | MFCD26142991 | 400.500 | C16H28N6O4S | 98.000 | [N-]=[N+]=NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 250mg | 247403111
LAB ALLEY Lab Alley Polyethylene Glycol (PEG) 400 Food Grade (FCC) Halal
Polyethylene Glycol is synthesized by ring-opening polymerization of ethylene oxide. This synthesis process gives PEG a range of molecular weights and distributions from 300 grams per mole to 10000000 grams per mole. PEG 400 has a molecular weight of 400 and is a clear colorless viscous liquid. Polyethylene Glycol is colorless inert odorless and non-volatile. PEG is biocompatible (it will not damage tissues or cells) hydrophilic dissolves readily in water without changing the color odor or taste and is nontoxic. Due to the high purity of Polyethylene Glycol 400 it is certified by the United States Pharmacopeia (USP) grade and the Food Chemicals Codex (FCC) grade.
eMolecules Biotin-PEG23-amine | 604786-74-5 | MFCD21363310 | 500mg
Broadpharm | Biotin-PEG23-amine | 500mg | 229582510 | BP-21959 | 94.000 | 604786-74-5 | MFCD21363310 | 1299.610 | C58H114N4O25S
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TARGETMOL CHEMICALS INC Biotin-PEG2-C2-iodoacetamide
Also available in 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis. Purity 98.01%
Cayman Chemical Boc-NH-PEG3-CH2CoH 50mg
A building block; has been used as a linker in the synthesis of PROTACs targeting MEK; has been used as a spacer in the synthesis of radiolabeled probes for dual labeling of tumor integrin αVβ3 and GRPR in tumor tissue in vivo
Medchemexpress LLC Azide-PEG5-tos | 236754-49-7 | 98.5% | 417.48 g·mol⁻¹ | C17H27N3O7S | 1 G
Azide-PEG5-Tos is a cleavable 5-unit polyethylene glycol (PEG) linker bearing an azide functional group and a tosyl terminus, designed for bioconjugation and ADC linker synthesis. The PEG spacer increases aqueous solubility and the azide enables click chemistry reactions such as CuAAC and SPAAC.
- Cleavable 5-unit PEG spacer increases aqueous solubility.
- Azide functional group enables CuAAC and SPAAC click reactions.
- Tosyl terminus acts as a leaving group for nucleophilic substitution.
- Available in multiple pack sizes, including 1 G.
- High purity (98.5%) and characterized molecular weight 417.48 g·mol⁻¹.
Medchemexpress LLC MC-VC-PABC-amide-PEG1-CH2-CC-885 | 2722697-82-5 | 99.9% | C55H68ClN11O13 | 1 MG
MC-VC-PABC-amide-PEG1-CH2-CC-885 is a neoDegrader-Linker conjugate consisting of the GSPT1 degrader/molecular glue CC-885 and a linker. This compound is utilized in the synthesis of Antibody-Drug Conjugates (ADCs) and Antibody neoDegrader Conjugates (AnDCs), which are designed to specifically degrade intracellular target proteins within target cells. It can be conjugated to various antibodies to form these conjugates.
- Consists of a GSPT1 degrader/molecular glue and a linker.
- Can be conjugated to various antibodies to form conjugates.
- Designed to specifically degrade intracellular target proteins within target cells.
- Utilized in the synthesis of antibody-drug conjugates (ADCs).
- Utilized in the synthesis of antibody neoDegrader conjugates (AnDCs).
![Carbosynth LLC. Cyclo[Arg-Gly-Asp-D-Tyr-Lys(PEG)], 1mg, MF= C33H52N10O11](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501952421.jpg-250.jpg)
Carbosynth LLC. Cyclo[Arg-Gly-Asp-D-Tyr-Lys(PEG)], 1mg, MF= C33H52N10O11
This item has a minimum order quantity of 3 per supplier requirements
Application: salt: Trifluoroacetate Salt, one letter code: c[RGDyK(PEG)], MW: 764.84
![eMolecules Broadpharm / N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) / 100mg / 784454967 / BP-29791 / 98.000 / / [null] / 1288.612 / C59H121N3O26](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502478464.JPG-250.jpg)
eMolecules Broadpharm / N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) / 100mg / 784454967 / BP-29791 / 98.000 / / [null] / 1288.612 / C59H121N3O26
Broadpharm / N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) / 100mg / 784454967 / BP-29791 / 98.000 / / [null] / 1288.612 / C59H121N3O26
Cayman Chemical dPE-PEG 2000 Cynur 1mg
A PEGylated form of DSPE; has been used in the generation of LNPs for the delivery of miRNA in vitro; LNPs containing DSPE-PEG(2000) cyanur, encapsulating let-7a miRNA, and conjugated to ephrin-A1 reduce the proliferation and colony formation and size of NCI H2081, NCI 5380, and A549 cancer cells, as well as reduce migration of NCI 5380 cells in a wound healing assay
Cayman Chemical STng PROTAC SP23 1mg
A PROTAC that drives STING degradation; degrades STING in THP-1 cells (DC50 = 3.2 µM); decreases cGAMP-induced increases in the levels of IFN-β, IL-6, and CXCL10 in THP-1 cells at 2.5-10 µM; reduces kidney weight, improves kidney function, and increases the survival rate in a mouse model of cisplatin-induced acute kidney injury at 30 and 60 mg/kg
Medchemexpress LLC Cyanine5 alkyne | 1223357-57-0 | 98.2% | C35H42ClN3O | 10MG
Cyanine5 alkyne is a near-infrared fluorescent dye bearing a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (click chemistry). It enables covalent labeling of azide-functionalized biomolecules for fluorescence imaging and detection in biochemical assays.
- Click-reactive terminal alkyne enables CuAAC conjugation.
- Near-infrared excitation and emission for reduced background in imaging.
- High purity suitable for sensitive fluorescence assays.
- Available in multiple milligram sizes for flexible experimental use.
- Stable when stored sealed away from moisture and light.
Medchemexpress LLC DSPE-NHS | 1383932-86-2 | MFCD34561791 | 95.0% | 945.21 g/mol | C49H89N2O13P | 5 MG
DSPE-NHS is an NHS-activated phospholipid reagent used for bioconjugation and liposome/nanocarrier preparation. It contains two hydrophobic stearoyl tails and an NHS ester that reacts with primary amines to form stable amide bonds; in aqueous solution it self-assembles into lipid bilayers and is commonly used to label antibodies and conjugate proteins.
- Reacts with primary amines to form stable amide linkages.
- Self-assembles into lipid bilayers in aqueous solution.
- Suitable for antibody labeling and protein conjugation.
- Solid form with practical storage recommendations for solvent and sealed conditions.
- Provided at high purity for research applications.