Protein Modification Reagents
![eMolecules PC-Biotin-PEG4 | Broadpharm |669.790 | C30H47N5O10S | 95.000 | CC(O)c1cc(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)ccc1[N+]([O-])=O | 250mg | 528284366](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183596.JPG-250.jpg)
eMolecules PC-Biotin-PEG4 | Broadpharm |669.790 | C30H47N5O10S | 95.000 | CC(O)c1cc(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)ccc1[N+]([O-])=O | 250mg | 528284366
PC-Biotin-PEG4 | Broadpharm |669.790 | C30H47N5O10S | 95.000 | CC(O)c1cc(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)ccc1[N+]([O-])=O | 250mg | 528284366
eMolecules 956348-61-1 | Propargyl-PEG24-amine | Broadpharm | MFCD30723251 | 1112.352 | C51H101NO24 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 340376890
Propargyl-PEG24-amine | Broadpharm | 956348-61-1 | MFCD30723251 | 1112.352 | C51H101NO24 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 340376890
eMolecules 2110448-97-8 | Gly-PEG3-amine, TFA salt | Broadpharm277.365 | C12H27N3O4 | 98.000 | NCCCOCCOCCOCCCNC(=O)CN | 250mg | 550804396
Gly-PEG3-amine, TFA salt | Broadpharm | 2110448-97-8277.365 | C12H27N3O4 | 98.000 | NCCCOCCOCCOCCCNC(=O)CN | 250mg | 550804396
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol, 3483-12-3, MFCD00004877, 1 G
Linear Formula: HSCH2CH(OH)CH(OH)CH2SH, Molecular Weight: 154.25, ≥98% (HPLC), ≥99.0% (titration), Synonym: threo-1,4-Dimercapto-2,3-butanediol, Cleland’s reagent, DTT. An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides.
Ubpbio TCEP Powder, 25 GR, CAS# 51805-45-9
Reducing Agents - TCEP - TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.
Medchemexpress LLC Carboxyethyl-γ-aminobutyric acid | 4386-03-2 | MFCD00057954 | 175.18 g/mol | C7H13NO4 | 10 MG
Carboxyethyl-γ-aminobutyric acid is a small-molecule biochemical reagent supplied as a powder for laboratory research. Identified by CAS 4386-03-2, it has formula C7H13NO4 and molecular weight 175.18 g/mol. Store and handle according to the safety data sheet and product documentation.
Medchemexpress LLC L-dithiothreitol | 16096-97-2 | MFCD00064305 | 98.0% | 154.25 g·mol⁻¹ | C4H10O2S2 | 10 MG
L-dithiothreitol (DTT) is a small-molecule thiol reducing agent used to cleave disulfide bonds and maintain cysteine residues in the reduced state during biochemical and molecular biology workflows. It is commonly used in sample preparation, protein analysis, and enzymatic assays.
- Effective reducing agent for cleaving disulfide bonds.
- Helps maintain proteins in a reduced, active state.
- Soluble in water and compatible with common buffers.
- High purity suitable for biochemical applications.
- Available in small quantities for analytical and research use.
Medchemexpress LLC PROTAC ERα Degrader-4 | 2521299-80-7 | 99.1% | 1074.23 | 5 MG
PROTAC ERα Degrader-4 (Compound ZD12) is a highly potent and selective PROTAC ERα degrader with a Ki of 5.08 μM. It contains OBHSAs, linker, and E3 ligase ligands, demonstrating excellent cell inhibitory and ERα degradation activity against Tamoxifen-sensitive and -resistant ER+ breast cancer (BC) cells and ERα-mutated BC cells. It can induce apoptosis and is suitable for cancer research.
- Highly potent and selective ERα degrader
- Contains OBHSAs, linker, and E3 ligase ligands
- Exhibits excellent cell inhibitory and ERα degradation activity
- Effective against Tamoxifen-sensitive and -resistant ER+ breast cancer (BC) cells
- Effective against ERα-mutated BC cells
- Induces apoptosis
- Suitable for cancer research
Medchemexpress LLC Protac BTK Degrader-1 | 2801715-13-7 | 98.87% | 749.86 | 5 MG
PROTAC BTK Degrader-1 is a potent, selective, and orally active PROTAC BTK degrader with IC50 values of 34.51 nM for BTK WT and 64.56 nM for BTK-481S. It effectively reduces BTK protein levels and suppresses tumor growth. This degrader is also a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent and selective degrader
- Orally active
- Reduces protein levels
- Suppresses tumor growth
- Click chemistry reagent