Immunohistochemistry Kits and Reagents
ABclonal Technology PDK1/PDHK1 Rabbit mAb
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
ABclonal Technology HBG1 Rabbit pAb
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is 5-epsilon -- gamma-G -- gamma-A -- delta -- beta--3.
Biocare Medical, LLC Vina Green Chromogen Kit - 100 ml
Vina Green is a novel permanent chromogen that produces a green stain in the presence of horseradish peroxidase (HRP). The kit consists of liquid Vina Green chromogen and buffer that are stable, when mixed, for at least 4 hours at room temperature. Vina Green is clearly distinguishable from Warp Red and DAB on a single slide, enabling high flexibility for its application in Multiplex IHC. Vina Green is suitable for both immunohistochemistry (IHC) and in situ hybridization (ISH) applications including HPV, CMV, EBV, Kappa, Lambda, p63, HMWCK, TTF-1, Ki-67, and other targets/antigens such as blood and lymphatic vessels, and basal and myoepithelial cells. The reaction product is insoluble in alcohols and xylene and, therefore, a variety of counterstains and permanent mounting media can be used with this chromogen kit.
ABclonal Technology Desmocollin 1 Rabbit mAb
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation A subtype of IgA pemphigus a life-threatening autoimmune disease is characterized by the presence of autoantibodies that target the encoded protein The desmosomal family members are arranged in two clusters on chromosome 18 Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein
Biolegend Alexa FluorR 647 anti-IBA1
Alexa Fluor 647 anti-IBA1 [A19290E] Isotype Mouse IgG2a Reactivity Human Apps ICFC Size 25 tests
ABclonal Technology Phospho-p38 MAPK-Y182 Rabbit mAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Medchemexpress LLC HY-P1883A 1mg Medchemexpress, Bacterial Sortase Substrate III, Abz/DNP (TFA) CAS: Purity:>98%
Medchemexpress, HY-P1883A 1mg Bacterial Sortase Substrate III, Abz/DNP (TFA) CAS: Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology GLI2 Rabbit mAb
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs These motifs contain conserved H-C links Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression It is also thought to play a role during embryogenesis The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome Pallister-Hall syndrome preaxial polydactyly type IV postaxial polydactyly types A1 and B
Bioss KD-Validated p38 MAPK Rabbit R
Mitogen-Activated Protein Kinase 14 Primary Antibody Unconjugated Public Immunogen Range 150-250/360 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
MilliporeSigma T DIAGNOSTICS CMV PP65 ANTIGEN
Life Sciences,Clinical Diagnostics & Infectious Disease,LIGHT DIAGNOSTICS CMV pp65 Antigenemia Antibody Set; ~125 tests; included in kit #3247
Abcam DoubleStain CL IHC Kit: G&Rt on human/mouse tissue (HRP/Green & AP/Red), 18ML
Abcam's Doublestain IHC Kit (ab183282) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Desmocollin 1 Rabbit mAb
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily These desmosomal family members along with the desmogleins are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation A subtype of IgA pemphigus a life-threatening autoimmune disease is characterized by the presence of autoantibodies that target the encoded protein The desmosomal family members are arranged in two clusters on chromosome 18 Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein
Immunology Consultants Anti-Human Beta 2 Microglobulin Antibody (Mouse - Clone #500) - Monoclonal
This mouse monoclonal antibody provides highly specific detection of human Beta‑2‑Microglobulin (β2M), a key component of MHC class I molecules and an important biomarker in immunology, oncology, and renal function studies. Clone 500 delivers strong affinity and low background, supporting sensitive detection in ELISA, Western blotting, flow cytometry, and antigen‑capture assays. Its clean, reproducible signal makes it suitable for quantitative assays, impurity monitoring, and characterization of β2M expression in cell‑based or purified samples. MB2‑80A‑500 offers consistent lot‑to‑lot performance, enabling reliable integration into research and diagnostic development workflows
Immunology Consultants anti-Hamster (CHO) Beta 2-Microglobulin Antibody - Affinity Purified
This affinity‑purified anti‑Hamster (CHO) Beta‑2‑Microglobulin (β2M) antibody provides a high‑specificity reagent for detecting this key component of MHC class I molecules in CHO‑derived systems. β2M is a widely monitored host cell protein due to its role in antigen presentation and its potential presence as a process‑related impurity in CHO‑based biologics manufacturing. Supplied at 0.1 mg, this antibody delivers consistent performance in ELISA, Western blotting, and other immunoassay formats. Its high affinity and CHO‑targeted specificity make it an excellent tool for HCP profiling, purification validation, and analytical method development where sensitive detection of β2M is required.