Immunohistochemistry Kits and Reagents
Biocare Medical, LLC Reveal Decloaker, RTU - 1 gal
Reveal Decloaker is a heat retrieval solution that is suitable for most antibody-antigen staining and reduces non-specific background staining, blocks endogenous peroxidase and removes mercury crystals. Reveal Decloaker can be used with Biocare's digital electric pressure cooker (Decloaking Chamber), a steamer, a water bath, or a microwave oven. For many antibodies, titers are doubled and background staining is significantly reduced when compared to citrate buffer, pH 6.0. Reveal Decloaker incorporates AssureTM technology, a color-coded high temperature pH indicator solution. The end-user is assured by visual inspection that the solution is at the correct dilution and pH. This product is specially formulated for superior pH stability at high temperatures and will help prevent the possibility of losing pH sensitive antigens. Reveal Decloaker is non-toxic, non-flammable, odorless and sodium azide and thimerosal free.
Biotium HIF1α(HIF1A-84), CF594 conjugate, 0.1mg/mL
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stab
ABclonal Technology p38 MAPK Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
ABclonal Technology PLVAP Rabbit pAb
Predicted to enable identical protein binding activity. Involved in MAPK cascade, positive regulation of cellular extravasation, and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea.
Revvity Health Sciences Inc HTRF Human Total ADAR1 Detection Kit, 500 Assay Points
HTRF Human Total ADAR1 Detection Kit, 500 Assay Points
Cayman Chemical NapsIn n-Term RabbIt Mon 100uL
A CaMKK inhibitor (IC50s 120 and 40 ng/ml for CaMKKa and CaMKKB respectively) selective for CaMKKs over CaMKI CaMKII CaMKIV MLCK PKC PKA and p42 MAPK (IC50s ≥ 10000 ng/ml for all) inhibits phosphorylation of CaMKI and AMPK in chicken sperm in the presence of extracellular calcium as well as reduces chicken sperm motility decreases Npy and Agrp expression and cumulative food intake in mice at 20 M 0.5 L/hour i.c.v. increases cortical striatal and total infarct volume in a mouse model of MCAO-induced focal transient cerebral ischemia at 3 g/animal i.c.v.
Diagnostic Biosystems UNOVUE RABBIT AP DETECTION REA UnoVue™ Rabbit AP Detection Reagent
The UnoVue Rabbit AP Detection Reagent is suitable for use with rabbit antibodies, both monoclonal and polyclonal. The reagents can be used for manual staining or with automated staining instruments and are well suited for multiplex immunohistochemical staining assays.
Abcam 3D Tissue Staining Pots ( x 10) – CUBIC, 1PACK
3D Tissue Staining Pots (x10) – CUBIC (ab316247) is part of the reagents, controls & accessories range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC DDR1 protein, human (HEK293, His) | >95.0% | 50 UG
DDR1 protein is the recombinant extracellular domain of human Discoidin Domain Receptor 1, produced in HEK293 mammalian cells and supplied with a C-terminal His tag as a lyophilized preparation for research use. It is suitable for binding studies, antibody characterization, and assay development, and is provided with purity and handling information in the accompanying documentation.
- Recombinant extracellular domain of human DDR1 expressed in HEK293 cells.
- Supplied with a C-terminal His tag for detection or purification.
- Lyophilized formulation with trehalose for stability during storage.
- Purity greater than 95% by SDS-PAGE.
- Molecular weight approximately 55-70 kDa, extracellular domain D21-T416.
- Store frozen; aliquot and avoid repeated freeze-thaw cycles.
Abcam Tissue Clearing Reagent 1 and 2 combo - hydrophobic, 30ML
Tissue Clearing Reagent 1 and 2 combo, ab243316, contains both clearing reagents, which are components of the complete kit: Tissue Clearing Kit ab243298.
The product is subject to the following: Abcam Restricted Use Statement
Bioss KD-Validated Desmin Rabbit Rec
Desmin Primary Antibody Unconjugated Public Immunogen Range 80-130/375 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Diagnostic Biosystems HRP PERM RED CHROMOGEN - 30MLS PermaRed™/HRP
PermaRed™/HRP is a substrate-chromogen system designed to be used for either IHC or ISH when utilizing horseradish peroxidase. PermaRed™/HRP can be permanently mounted to produce a strong red brick color that can be easily distinguished from other stains.
Meso Scale Discovery R-PLEX Human Calbindin ASY
The R-PLEX Human Calbindin Assay from Meso Scale Diagnostics is a multiplex immunoassay for measuring calbindin in human serum plasma urine and other fluids It uses electrochemiluminescence (ECL) detection for high sensitivity a wide dynamic range and low sample volume This assay quantifies calbindin a calcium-binding protein in the intestine and kidneys aiding in diagnosing diseases related to calbindin levels The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and necessary reagents