Immunohistochemistry Kits and Reagents
Abcam DoubleStain CL IHC Kit: G&Rt on human/mouse tissue (HRP/Green & AP/Red), 6ML
Abcam's Doublestain IHC Kit (ab183282) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Seracare Life Sciences Inc BLOCKING SOLUTION CONCENTRATE
Blocking solution concentrate is used in immunohistochemistry applications where endogenous peroxidase activity causes non-specific signal and high background. Supplied as a 10X concentrate; working solution is prepared by diluting 1:10 in reagent quality water. Also available as part of HistoMark TrueBlue, HistoMark ORANGE and HistoMark BLACK substrate kits.
Medchemexpress LLC DDR1 protein, mouse, HEK293-expressed, C-terminal His-tag | >95.0% | 50 UG
Recombinant mouse Discoidin Domain Receptor 1 (DDR1) fragment (D20-T414) expressed in HEK293 cells and supplied as a C-terminal His-tagged solution in PBS. The protein is purified (>95% by reducing SDS-PAGE), 0.22 μm filtered, and provided in amounts including a 50 μg vial. Store at -80°C and ship on dry ice. Suitable for biochemical assays and antibody validation.
- Species: mouse
- Expression system: HEK293 cells
- Tag: C-terminal His
- Sequence range: D20-T414 (accession Q03146-2)
- Purity: >95% by reducing SDS-PAGE
- Formulation: 0.22 μm filtered PBS, pH 7.4, solution
- Storage: store at -80°C; shipped on dry ice
- Applications: binding assays, antibody validation, and cell signalling studies
ABclonal Technology Calbindin Rabbit pAb
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.
ABclonal Technology PLVAP Rabbit pAb
Predicted to enable identical protein binding activity. Involved in MAPK cascade, positive regulation of cellular extravasation, and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea.
ABclonal Technology MAP2 Rabbit mAb
This gene encodes a protein that belongs to the microtubule-associated protein family The proteins of this family are thought to be involved in microtubule assembly which is an essential step in neurogenesis The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites implicating a role in determining and stabilizing dentritic shape during neuron development A number of alternatively spliced variants encoding distinct isoforms have been described
Biotium Cytokeratin 8(H1 + TS1), CF740 conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Biotium CD6(C6/372), CF594 conjugate, 0.1mg/mL
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ABclonal Technology Phospho-p38 MAPK-T180 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Biotium Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16, Biotin conjugate, 0.1mg/mL
This antibody recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes of
Biotium Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (rCDH16/1071), Biotin conjugate, 0.1mg/mL
This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exc
Cayman Chemical S-p38 MAPK InhIbItr III 500ug
A methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro); potently blocks the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively)
Biotium Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (CDH16/1532R), Biotin conjugate, 0.1mg/mL
This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer excep
Abcam TripleStain IHC Kit: R&R&M on human tissue (DAB, AP/Red & Green/HRP), 18ML
Abcam's TripleStain IHC Kit (ab183288) is designed to be used with one mouse and two rabbit primary antibodies, supplied by the user, to detect three distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
MOLECULAR DEPOT LLC Beta-2 Microglobulin Ab -50 mg
Human Beta-2 Microglobulin Antibody is a Goat polyclonal antibody specific to human Beta-2 microglobulin This IgG fraction purified antibody has been tested in several immunoassays For in vitro research use only