Immunohistochemistry Kits and Reagents
Biotium S100B(S100B/1012), CF594 conjugate, 0.1mg/mL
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and case
Biotium Hydroxystilbamidine
Hydroxystilbamidine (also called Fluoro-Gold) has been used extensively as a retrograde tracer for neurons and also a histochemical stain. Fluoro-Gold can undergo retrograde axonal transport, it shows extensive filling of dendrites, and has a high resistance to fading. Also see hydroxystilbamidine 4% in H2O, which is a more convenient, ready-to-use form. Properties: Ex/Em = 361/536 nm; Yellow solid soluble in water; Store at 4°C and protect from light; C18H24N4O7S2; MW: 473; [223769-64-0].Fluoro-Gold is a trademark of Fluorochrome, LLC.
Biotium NKX2.2(NX2/294), CF594 conjugate, 0.1mg/mL
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD86(BU63), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 70 kDa, which is identified as CD86. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4, a cancer immunotherapy target. It is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. N
Biotium CMV-p65(CMV101), CF594 conjugate, 0.1mg/mL
Ten to forty percent of the patients with acquired immunodeficiency syndrome (AIDS) develop cytomegalovirus (CMV) infections. In some patients with AIDS, CMV is detected in the bronchoalveolar lavage fluid (BALF), urine, and other specimens, even when there are no symptoms of CMV disease. An indicator of active CMV infection is needed to facilitate the diagnosis of CMV disease in patients with AIDS or HIV infection. CMV p65 antigen was detected in the leukocytes of both the peripheral blood and BALF during the early phase of CMV disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Abcam DoubleStain CL IHC Kit: G&Rt on human/mouse tissue (HRP/Green & AP/Red), 6ML
Abcam's Doublestain IHC Kit (ab183282) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DoubleStain IHC Kit: G&M on human tissue (Green/HRP & AP/Red), 6ML
Abcam's DoubleStain IHC kit (ab183272) is designed to use with user supplied goat and mouse antibodies to detect two distinct antigens on human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences PATHO-GENE HPV type 16 18 31 33 51 probe (1ml)
The PATHO-GENE HPV type 16/18/31/33/51 probe is a mixture of biotin-labeled HPV-16, HPV- 18, HPV-31, HPV-33 and HPV-51 specific probes in buffered formamide and hybridization enhancers. Long Term Storage: +4°C.
Enzo Life Sciences MITO-ID Red detection kit (GFP-CERTIFIED) (500tests)
MITO-ID Red Detection Kit (GFP-CERTIFIED) contains a proprietary membrane-permeable mitochondria-selective dye suitable for use with live-, detergent-permeabilized- and even aldehyde-fixed-cells. Unlike conventional dyes, such as DiOC6(3), JC-1, rhodamine 123 and tetramethylrhodamine ethyl ester, MITO-ID Red dye highlights mitochondria regardless of their energetic state. The dye is compatible with most fluorescence detection systems, including conventional and confocal fluorescence microscopes, as well as, High Content Screening (HCS) platforms. The kit is useful for assessing mitochondrial morphology changes, estimating mitochondrial mass and co-localizing GFP-tagged proteins to the mitochondrial compartment. Wavelength maxima: MITO-ID Red λex 558 nm, λem 690 nm; Hoechst 33342 λex 350 nm, λem 461 nm. Applications: Fluorescence microscopy, Fluorescent detection .
Perkin Elmer US LLC Front Plate for Auto Sipper Accessory for LAMBDA 365
The Front Plate for the Auto Sipper Accessory enables the tube connections between the Auto Sipper and the LAMBDA 365 spectrometer.
Cayman Chemical S-p38 MAPK InhIbItr III 10mg
A methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro); potently blocks the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively)
Abcam Tissue Clearing Washing Buffer 10 x - hydrophobic, 70ML
Tissue Clearing Washing Buffer ab243306 is part of our range of tissue clearing reagents and products that enable you to set up tissue clearing easily and quickly.
The product is subject to the following: Abcam Restricted Use Statement
World Precision Instrument Kit, CABLAY ISO-DAM8A, unterminated
- Unterminated, 5' multi-strand cable on an 8-pin DIN
Biotium CD70(BU69), CF594 conjugate, 0.1mg/mL
This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blu