Non-Mammalian cDNA
ABclonal Technology SLC18A3 Rabbit pAb
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
ABclonal Technology CD64 Rabbit pAb
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Medchemexpress LLC 9β,10α-Cholesta-5,7-dien-3β-ol | 5226-01-7 | 99.5% | 384.64 | 10 MG
Lumisterol 3 (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosteroid metabolite, classified as a vitamin D3 photoisomer derivative. It is used in the preparation of vitamin D.
- Source: endogenous metabolite, human gut microbiota metabolites
- Appearance: solid, off-white to light yellow
- Molecular formula: C27H44O
- Structure classification: steroids
- Shipping: shipped with dry ice
- Storage: -80°C, protected from light, under nitrogen. Solutions are unstable, freshly prepared recommended.
- Biological activity: reduces UVB-induced cellular oxidant formation, inhibits proliferation of UVB-irradiated keratinocytes, promotes cellular DNA damage repair, increases nuclear/cytosolic Nrf2 ratio and nuclear p53 expression, enhances Nrf2-regulated antioxidant proteins.
Cell Signaling Technology PathScanR TotalPD-L1 Sandwich ELISA Kit 10 Kit
PathScanR TotalPD-L1 Sandwich ELISA Kit 10 Kit
ABclonal Technology ErbB3/HER3 Rabbit pAb
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. It has a neuregulin binding domain but lacks an active kinase domain, so it binds the ligand without transmitting signals via protein phosphorylation. It forms heterodimers with other EGFR family members that have kinase activity, activating pathways for cell proliferation or differentiation. Amplification or overexpression of this gene is linked to various cancers, including prostate, bladder, and breast tumors. Alternative splice variants encoding different isoforms have been identified, including one isoform that lacks the intermembrane region and is secreted to modulate the membrane-bound form’s activity. Other splice variants have been reported but are not fully characterized.
Medchemexpress LLC DRB18 | 2863686-81-9 | 99.6% | C22H23ClN2O2 | 50 MG
DRB18 is a potent pan-class GLUT inhibitor that modifies energy-related metabolism in A549 cells by altering metabolite abundance in glucose-related pathways. This can result in G1/S phase arrest, increased oxidative stress, and necrotic cell death. It has demonstrated anti-tumor activity.
- Potent pan-class GLUT inhibitor
- Modifies energy-related metabolism in A549 cells
- Leads to G1/S phase arrest
- Increases oxidative stress
- Causes necrotic cell death
- Demonstrates anti-tumor activity
- Reduces glucose uptake in HEK293 cell lines
- Inhibits tumor volume and weight in xenografted tumors
American Research Products Inc AntiHuman CD64
Anti-Human CD64 (FCGR1) In Vivo Antibody - Low Endotoxin is a in vivo antibody with human reactivity produced in mouse Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
Cayman Chemical 8 12-Iso-IPF2a-VI 10ug
The most abundant isoprostane product formed during lipid peroxidation; detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and CSF of patients with Alzheimer’s disease
Medchemexpress LLC PRKCI protein, human recombinant (Sf9, His tag) | 10UG
Recombinant human PRKCI protein expressed in Sf9 insect cells and purified with a His tag. Supplied as a 0.22 μm filtered solution in a Tris-based buffer with glycerol and stabilizers, the protein is intended for biochemical assays, signaling studies, and reagent validation. Ship on dry ice; store at -80°C for long-term stability and avoid repeated freeze-thaw cycles.
- Recombinant human protein expressed in Sf9 insect cells
- His tag for straightforward purification and detection
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays
- Provided in Tris buffer with NaCl, GSH, PMSF, and 10% glycerol for stability
- Shipped on dry ice and stable at -80°C for long-term storage
American Research Products Inc AntiHuman CD64
Anti-Human CD64 (FCGR1) In Vivo Antibody - Low Endotoxin is a in vivo antibody with human reactivity produced in mouse Available in 100 mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
ABclonal Technology Integrin beta 4 (ITGB4/CD104) Rabbit pAb
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
ABclonal Technology INSRR Rabbit pAb
Enables transmembrane receptor protein tyrosine kinase activity. Involved in actin cytoskeleton reorganization, cellular response to alkaline pH, and protein autophosphorylation. Part of receptor complex.