General Cell Based Assays
Meso Scale Discovery U-PLEX Mouse IL-4 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IL-4 Assay Kit is an electrochemiluminescent immunoassay for quantifying mouse interleukin 4 (IL-4) in various samples It uses MSD s SECTOR Imager to detect signals from microplate wells The kit includes a capture antibody for IL-4 and a ruthenium-labeled detection antibody It has a detection range of 0 05-1000 pg/mL with no cross-reactivity with other cytokines The kit provides a 96-well plate detection antibody calibrators 10X diluent and components for 96 tests
Meso Scale Discovery R-PLEX Human ADAM17 ASYQP
The R-PLEX Human ADAM17 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active ADAM17 in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity and a broad dynamic range This kit includes a 96-well plate coated with capture antibody detection antibody Read Buffer and calibrator The assay can detect ADAM17 levels between 0 3-1000 pg/mL and requires only 50 L of sample
ABclonal Technology Cathepsin B Rabbit pAb
This gene encodes a member of the C1 family of peptidases. Alternative splicing results in multiple transcript variants, with at least one encoding a preproprotein that is processed into cathepsin B light and heavy chains, which dimerize to form the active enzyme. Cathepsin B is a lysosomal cysteine protease with endopeptidase and exopeptidase activity, involved in protein turnover. It also acts as amyloid precursor protein secretase, with incomplete APP processing linked to Alzheimers disease. Overexpression of this protein is associated with esophageal adenocarcinoma and other cancers. Both cathepsin B and L are involved in cleaving the spike protein of SARS-CoV-2 during cell entry. Multiple pseudogenes of this gene have been identified.
Eurofins Discoverx cAMP Hunter eXpress CXCR4 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0081E2CP2L)
The cAMP Hunter CXCR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL12/SDF-1α) based activation of CXCR4 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CXCR4, a naturally Gi/Go coupled GPCR. Upon activation of CXCR4, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress DDR1 Functional Assay, 2-Plate Kit. (93-0894E3CP16M)
The PathHunter eXpress DDR1 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated DDR1 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged DDR1 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Epoetin Alfa Bioassay Kit, 10pl. (93-0965Y3-00018)
The PathHunter Epoetin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses erythropoetin or epoetin alfa-induced dimerization of EPOR receptors. This product uses EFC technology. The cell line included overexpresses EPOR target protein fused to PK alongside EPOR target protein fused to EA. Upon ligand-induced dimerization of EPOR, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress SREBP2 Nuclear Translocation Assay, 10pl Kit. (93-0830E3CP5L)
The PathHunter eXpress SREBP2 Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the cholesterol biosynthesis pathway. This kit assesses ligand (e.g. 5'-UMP) based pathway activation via detection of resulting SREBP2 nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged SREBP2 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of SREBP2 leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eagle Biosciences Inc iLite® FGF-21 Assay Ready Cells
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation. The mature plasma protein is composed of apparently identical subunits (Mr=260,000) which are held together by disulfide bonds.
Revvity Health Sciences Inc AlphaScreen FITC Detection Kit, 50,000 Assay Points
AlphaScreen FITC Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Terbium cryptate Labeling Detection Kit
HTRF Terbium cryptate Labeling Detection Kit
Revvity Health Sciences Inc HTRF Human Phospho-AKT1/2/3 (Thr308) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-AKT1/2/3 (Thr308) Detection Kit, 10,000 Assay Points
Crescent Chemical Co Inc SINGLEQUANT ASSAY KIT
SingleQuant Assay Kit Single tube format assay kit for protein quantification. The assay bases on the precipitation of proteins as insoluble dye complexes with acidic, ethanolic amido black 10B solution (1,2). After precipitation the protein-dye complexes are spinned
Apexbio Technology LLC CA PHOSPH CELL TRAN KIT 100T
CA PHOSPH CELL TRAN KIT 100T APEXBIO TECHNOLOGIES
Cell Signaling Technology Malachite Green Phosphate Dete
Malachite Green Phosphate Detection Kit 1 Kit
