General Cell Based Assays
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-NF-κB (Ser536) Detection Kit, 50,000 Assay Points
Cayman Chemical Bilirubin Conjugate (sodium salt), Purity: ≥95%, CAS: 68683-34-1, 500 mg
A stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives; exhibits anti-oxidant and antimutagenic effects
Revvity Health Sciences Inc HTRF Human & Mouse Total STAT1 Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Total STAT1 Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter eXpress GIPR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-1095E2CP2M)
The PathHunter GIPR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GIP) based activation of GIPR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GIPR and EA-tagged β-Arrestin-2. Activation of GIPR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Pan-Phospho- EGFR Detection Kit, 10,000 Assay Points
HTRF Human Pan-Phospho- EGFR Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter eXpress OPRM1 U2OS β-Arrestin-1 GPCR Assay, 10-Plate Kit. (93-0878E3CP5L)
The PathHunter OPRM1 (ARR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-1. Activation of OPRM1 stimulates the recruitment of β-Arrestin-1 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mGIPR U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0846E3MCP5L)
The PathHunter mGIPR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GIP) based activation of mGIPR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGIPR and EA-tagged β-Arrestin-2. Activation of mGIPR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rCHRM4 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0870E2RCP2L)
The PathHunter rCHRM4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. acetylcholine) based activation of rCHRM4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rCHRM4 and EA-tagged β-Arrestin-2. Activation of rCHRM4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam LDH Assay Kit¿(Cytotoxicity)
LDH Assay Kit¿(Cytotoxicity)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress IL7R/IL2RG Dimerization Assay, 10pl Kit. (93-0997E13CP0L)
The PathHunter IL7R/IL2RG Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-7) induced dimerization of IL7R/IL2RG receptors. This product uses EFC technology. The cell line included overexpresses IL7R target protein fused to PK alongside IL2RG target protein fused to EA. Upon ligand-induced dimerization of IL7R/IL2RG, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress PROKR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0090E2CP2M)
The cAMP Hunter PROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PROKR1, a naturally Gs coupled GPCR. Upon activation of PROKR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human DRD2L β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human DRD2L β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure DRD2L (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx InCELL Hunter eXpress MEK1 Kinase Binding Assay, 10pl Kit. (96-0040E15CP0L)
The InCELL Hunter eXpress MEK1 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of MEK1 via detection of MEK1 levels. This product uses EFC technology. The cell line included overexpresses MEK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.