General Cell Based Assays
Abcam Creatinine Assay Kit (Colorimetric)
Creatinine Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cholesterol/Cholesteryl Ester Assay Kit - Detection
Cholesterol/Cholesteryl Ester Assay Kit - Detection
The product is subject to the following: Abcam Restricted Use Statement
Abcam INOSINE QUANTIFICATION ASSAY K ..
INOSINE QUANTIFICATION ASSAY K ..
The product is subject to the following: Abcam Restricted Use Statement
AMERICAN RESEARCH PRODUCTS INC MO SRBD DELTA B16172 SIGA KIT
503008484 MO SRBD DELTA B16172 SIGA KIT
Bioss Actin Fruit Fly Loading Cont
Actin (Fruit Fly Loading Control) Primary Antibody Unconjugated Host Species Rabbit Target Species Clonality Monoclonal Applications WB Concentration 1mg/ml Size 100 ul Storage Buffer 0 01M TBS(pH7 4) with 1% BSA 0 02% Proclin300 and 50% Glycerol
Apexbio Technology LLC DiscoveryProbe™ PI3K/Akt/mTOR Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe PI3K/Akt/mTOR Compound Library comprises 178 small molecule inhibitors targeting PI3K/Akt/mTOR-related signaling pathways This pathway regulates processes such as cell growth proliferation survival apoptosis and metabolism in various cell types making it a frequent focus for oncology and disease mechanism research The collection encompasses compounds approved by regulatory agencies including FDA and EMA and agents studied extensively in academic and pharmaceutical research settings Representative inhibitors within this library include PI3K-selective inhibitors ATM/ATR inhibitors (DNA damage response regulators) and DNA-PK and GSK-3 targeting compounds providing comprehensive coverage for biological pathway elucidation drug discovery screening and pharmacological mechanism-of-action studies
Eurofins Discoverx PathHunter eXpress FGFR4-β-Klotho Functional Assay, 10pl Kit. (93-1060E3CP0L)
The PathHunter eXpress FGFR4-β-Klotho Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated FGFR4 and β-Klotho dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FGFR4 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, β-Klotho. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress MCHR2 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0691E3CP5M)
The PathHunter MCHR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. MCH) based activation of MCHR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MCHR2 and EA-tagged β-Arrestin-2. Activation of MCHR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EphB3 Functional Assay, 10-Plate Kit. (93-0842E3CP16L)
The PathHunter eXpress EphB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB3 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress BLK Activity Assay, 10-Plate Kit. (93-0882E3CP16L)
The PathHunter eXpress BLK Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the BLK kinase domain. The cell line is engineered to express the catalytic domain from BLK fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the BLK catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.