General Cell Based Assays
Eurofins Discoverx PathHunter Human MIP-1α (CCR1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MIP-1α (CCR1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx AssayComplete Cell Plating 29 Reagent, 500. (93-0563R29B)
AssayComplete Cell Plating 29 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Meso Scale Discovery R-PLEX Mouse RBP4 ASY
The R-PLEX Mouse RBP4 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures RBP4 levels in mouse serum plasma and tissue culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluents needed to perform the assay The kit can quantitatively measure RBP4 levels with high precision and accuracy It is suitable for studying RBP4 biology and evaluating RBP4 as a biomarker
Cayman Chemical FFAR4GPR120 Reporter asy 1ea
An IRE1a inhibitor (IC50s 0.2 and 0.02 UM for RNase and kinase activity respectively) selective for IRE1a over Ron and FGFR1 (IC50s 4.4 and 17 UM) as well as a panel of 282 kinases at 10 UM inhibits ER stress-induced increases in the splicing of mRNA encoding XBP1 in eight multiple myeloma cell lines at 8 UM reduces viral replication in tick-borne encephalitis virus-infected SH-SY5Y and SNB-19 cells at 0.5 UM and tick-borne encephalitis virus-infected Caco-2 cells at 1 UM
Cayman Chemical NADP hydrate 100mg
The oxidized form of NADPH; serves as a cofactor in various biological reactions
American Research Products Inc Mouse Alanine Aminotransferase
Mouse Alanine Aminotransferase (ALT/GPT) ELISA Kit from CUSABIO Detection Range 0 156 mU/mL-10 mU/mL Sensitivity 0 039 mU/mL Sample serum plasma cell culture supernates cell lysates Method Sandwich
American Research Products Inc Mouse Macrophage Migration Inh
Mouse Macrophage Migration Inhibitory Factor MIF ELISA Kit from CUSABIO Detection Range 125 pg/ml - 8000 pg/ml Sensitivity 31 25 pg/ml Sample serum plasma tissue homogenates Method Sandwich
American Research Products Inc Rat tissue inhibitors of metal
Rat tissue inhibitors of metalloproteinase 2 TIMP-2 ELISA Kit from CUSABIO Detection Range 1 25 ng/mL-80 ng/mL Sensitivity 0 31 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx PathHunter eXpress DRD4 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0690E2CP0M)
The PathHunter DRD4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD4 and EA-tagged β-Arrestin-2. Activation of DRD4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Complement C3a (C3AR1) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human Complement C3a (C3AR1) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure C3AR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter CNR1 Bioassay Kit, 2-Plate. (93-0959Y2-00119)
The PathHunter CNR1 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. CP 55,940) based activation of CNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CNR1 and EA-tagged β-Arrestin-2. Activation of CNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Human NMBR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human NMBR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NMBR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human SSTR5 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human SSTR5 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure SSTR5 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Urease asy Reagent 1ea
A sesquiterpenoid with diverse biological activities selectively RXRB over RXRa and RXRY in reporter assays using HEK293T cells (EC50s 5.2 27 and 43 UM respectively) as well as RARs PPARs LXRs FXR CAR VDR and PXR at 30 UM enhances GABA-induced activation of a1B2Y2-subunit containing GABA receptors in CHO cells (EC50 12.6 UM) cytotoxic to GLC-4 and COLO 320 cells (IC50s 127 and 124 UM respectively) decreases motor performance in the rotarod test and increases pentobarbital-induced sleeping time in mice at 100 mg/kg i.p. increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice indicating anxiolytic-like activity at 12 mg/kg
Eurofins Discoverx PathHunter Human RXFP4 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human RXFP4 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure RXFP4 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.