General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Phospho-p53 (Ser15) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-p53 (Ser15) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-PLC-γ1 (Tyr783) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-PLC-γ1 (Tyr783) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse PARP cleaved-Asp214 Detection Kit, 500 Assay Points
HTRF Human & Mouse PARP cleaved-Asp214 Detection Kit, 500 Assay Points
Sigma Aldrich Fine Chemicals Biosciences Ras Assay Reagent Raf 1 RB
Product Source Human Ras Binding Domain (RBD residues 1-149) of Raf-1 expressed in E. coli.
Sigma Aldrich Fine Chemicals Biosciences Proteasome 20S Activity As
Protein degradation occurs most commonly through two major mechanisms lysosomal degradation and proteasome mediated degradation. Lysosomal degradation occurs through proteolytic enzyme activity and is fairly non-specific. Proteasomal degradation is targeted for a specific protein through the ubiquitination of the target protein. The target protein is typically poly-ubiquitinated and activates the 26S proteasome toward proteolysis. The proteasome 26S is the most common form of the proteasome and is an ATP-dependent proteolytic complex which contains one 20S (700-kDa) core particle structure and two 19S (700-kDa) regulatory caps.The proteasome is responsible for the recycling of proteins and maintenance of the balance of protein synthesis and degradation. The proteasome is involved with apoptosis DNA repair endocytosis and cell cycle and has been implicated in disease states such as certain types of cancer diabetes mellitus and Alzheimer disease among others making it the target f
Sigma Aldrich Fine Chemicals Biosciences Sulfate Assay Kit sufficie
Inorganic sulfate is one of the most abundant anions in mammalian plasma. Sulfate plays important physiological roles in activating and detoxifying xenobiotics steroids neurotransmitters and bile acids. Sulfate is needed for the biosynthesis of cerebroside sulfate glycosaminoglycans and heparin sulfate. Undersulfation of cartilage proteoglycans has been associated with human inherited osteochondro-dysplasia disorders. In mammals sulfate homeostasis is regulated by the kidney. The majority of filtered sulfate is absorbed in the proximal tubules and only 5-20% of the filtered load is excreted into the urine.
Sigma Aldrich Fine Chemicals Biosciences Invertase Activity Assay K
Invertase (beta-fructofuranosidase) is an enzyme that catalyzes the hydrolysis of sucrose to fructose and glucose. Invertase is produced by certain plants microorganisms and honey bees.
Eurofins Discoverx PathHunter eXpress CNR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0959E2CP0L)
The PathHunter CNR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CP 55,940) based activation of CNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CNR1 and EA-tagged β-Arrestin-2. Activation of CNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress BRS3 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0945E2CP2M)
The PathHunter BRS3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. bombesin) based activation of BRS3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BRS3 and EA-tagged β-Arrestin-2. Activation of BRS3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EpoR/EpoR Dimerization Assay, 10-Plate Kit. (93-0965E3CP0L)
The PathHunter EpoR/EpoR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. erythropoietin) induced dimerization of EpoR/EpoR receptors. This product uses EFC technology. The cell line included overexpresses EpoR target protein fused to PK alongside EpoR target protein fused to EA. Upon ligand-induced dimerization of EpoR/EpoR, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress ACVRL1/ACVR2B Dimerization Assay, 2pl Kit. (93-0964E3CP22M)
The PathHunter ACVRL1/ACVR2B Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. GDF2/BMP9) induced dimerization of ACVRL1/ACVR2B receptors. This product uses EFC technology. The cell line included overexpresses ACVRL1 target protein fused to PK alongside ACVR2B target protein fused to EA. Upon ligand-induced dimerization of ACVRL1/ACVR2B, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human IP-10 ASY
The Meso Scale Discovery U-PLEX Human IP-10 Assay is an electrochemiluminescent immunoassay for the quantitative measurement of human interferon gamma-induced protein 10 (IP-10) in serum plasma and cell culture supernatants It utilizes MSD s proprietary SECTOR Imager 6000 for high sensitivity and a wide dynamic range The assay has high specificity with no cross-reactivity and 1% interference It requires 50 L or less sample volume and has an ultra-low lower limit of detection of 45 fg/mL The assay takes 3 5 hours for completion This powerful and sensitive assay allows reliable quantification of IP-10 across a wide range of concentrations
Cayman Chemical NBD-Fructose 10mg
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Abcam Protein Tyrosine Phosphatase Assay Kit
Protein Tyrosine Phosphatase Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam AMP Assay Kit (Colorimetric)
AMP Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement