General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 500 Assay Points
HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human IL-2 Detection Kit, 96 Assay Points
HTRF Human IL-2 Detection Kit, 96 Assay Points
Revvity Health Sciences Inc HTRF Human Total cGAS Detection Kit, 500 Assay Points
HTRF Human Total cGAS Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress HTR2C Activated GPCR Internalization Assay, 2pl Kit. (93-0669E3CP27M)
The PathHunter HTR2C Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of HTR2C via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged HTR2C. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting HTR2C-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ION BIOSCIENCES Brilliant Lithium Assay Flex kit - 10 plates
ION Biosciences’ Brilliant Lithium Assay Flex kit is a next-generation, fluorescence-based approach for high-throughput screening of NaV1.X channel modulators. The assay uses ION Lithium Green 1 AM (ILG-1 AM), a membrane-permeable, lithium-sensitive fluorescent dye that enables functional voltage-gated sodium channel measurements using lithium as a surrogate ion. Lithium readily permeates open NaV1.X channels while bypassing many endogenous sodium-handling mechanisms, resulting in a robust and selective readout of channel activity. Upon depolarization or pharmacological activation of NaV1.X channels, lithium accumulates intracellularly producing a rapid, quantifiable fluorescence increase that reflects real time channel activity. 10-plate kit.
ION BIOSCIENCES Brilliant Calcium Assay Flex kit - 10 plates
ION Biosciences’ Brilliant Calcium (Ca²⁺) Assay Flex kit is a total assay solution for multi-well plate-based, high-throughput measurements of dynamic changes in intracellular Ca²⁺. The ION Biosciences’ Brilliant Calcium Assay is useful for a wide range of effectors of intracellular Ca²⁺ including many G protein-coupled receptors (GPCRs), divalent cation channels, and other proteins capable of transporting Ca²⁺ or affecting intracellular Ca²⁺ dynamics. In multi-well, plate-based formats, the Brilliant Calcium Assay can be used to discover and characterize the effects of tens to many tens-of-thousands of compounds and environmental factors which can act to affect intracellular Ca²⁺ levels. 10-plate kit.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0442
PhosphoSens-Kinetic Phosphatase Activity Kit 1000 assays - AQT0442