General Cell Based Assays
Abcam MnTBAP chloride, Supero x ide dismutase (SOD) mimetic, 10MG
MW 879.1 Da. Cell-permeable SOD mimetic. Potent peroxynitrite scavenger. Does not scavenge NO. Shows anti-inflammatory effects and reduces oxidative injury in vivo. Reduces ROS and shows a neuroprotective effect in spinal cord injury.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc Rat SuperoXide dismutase Mn
Rat SuperoXide dismutase [Mn] mitochondrial (SOD2) ELISA kit from CUSABIO Detection Range 1 87 pg/mL-120 pg/mL Sensitivity 0 47 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Sigma Aldrich Fine Chemicals Biosciences Indican Assay Kit sufficie
Indican (indoxyl sulfate) is a putrefaction product resulting from bacterial deconjugation of tryptophan in the small intestine. Indican is water soluble and excreted through urine. Increases in urine indican can indicate protein maldigestion or malabsortion or the overgrowth of gut anaerobic bacteria. Indican levels in urine can also increase in response to a high protein diet.
Eurofins Discoverx PATHHUNTER U2OS TRKA-P75 BIOAS
PathHunter U2OS TrkA-p75 Bioassay Kit, 1,000 dp (10 x 96-well).
Eurofins Discoverx PathHunter eXpress HTR2C Activated GPCR Internalization Assay, 2pl Kit. (93-0669E3CP27M)
The PathHunter HTR2C Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of HTR2C via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged HTR2C. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting HTR2C-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR182 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0754E2CP1L)
The PathHunter GPR182 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR182 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR182 and EA-tagged β-Arrestin-2. Activation of GPR182 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Montana Molecular TMPRSS2 BacMam - 30mL
TMPRSS2 packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures including A549s and HUVECs. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. This kit includes the TMPRSS2 BacMam and 500mM sodium butyrate in H2O. Use with other Montana Molecular tools including Pseudo-SARS-CoV-2 and BacMam-packaged ACE2, Neuropilin-1, and Cathepsin-L.
Genscript Corporation ToxinSensor Single Tests Kit
GenScript ToxinSensor Single Tests Kit with Standard is designed to be a qualitative In Vitro end-point endotoxin test for human and animal parenteral drugs biological products and medical devices Tachypleus Amebocyte Lysate (TAL) as supplied is to be reconstituted with sample or control directly After incubation for 1 hour and in the presence of endotoxin gelation occurs in the absence of endotoxin gelation does not occur GenScript supply a series of ToxinSensorTM Single Tests Kits with Standard with different sensitivity (0 03 EU/ml 0 06 EU/ml 0 125 EU/ml and 0 25 EU/ml)
Eurofins Discoverx PathHunter Mouse CRTH2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse CRTH2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mCRTH2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biochain Institute Inc ATP Assay Kit, 100; assays/PK
BioChain's EnzyLightTM ATP Assay Kit provides a rapid method to measure intracellular ATP. The single working reagent lyses cells to release ATP, which, in the presence of luciferase, immediately reacts with the Substrate D-luciferin to produce light. The light intensity is a direct measure of intracellular ATPconcentration. This non-radioactive, homogeneous cell-based assay is performed in microplates. The reagent is compatible with all culture media and with all liquid handling systems for high throughput screning.
Eurofins Discoverx PathHunter eXpress mADORA2B CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0469E2MCP0M)
The PathHunter mADORA2B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. NECA) based activation of mADORA2B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mADORA2B and EA-tagged β-Arrestin-2. Activation of mADORA2B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mEDG1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0476E2MCP4M)
The PathHunter mEDG1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. S1P) based activation of mEDG1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mEDG1 and EA-tagged β-Arrestin-2. Activation of mEDG1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.