General Cell Based Assays
TARGETMOL CHEMICALS INC P38 MAPK INHIBITOR 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS. purity: 99%
Abcam Cell Tracking Dye Kit - Green - Cytopainter
Cell Tracking Dye Kit - Green - Cytopainter
The product is subject to the following: Abcam Restricted Use Statement
Indigo Biosciences Human Pregnane X Receptor (PXR, NR1I2) All-inclusive Cell-Based Luciferase Reporter Assay Kit, 384-well assay plate format
Eliminate weeks of cell culture while achieving superior sensitivity with reproducible results from this all-inclusive cell-based luciferase reporter assay. INDIGO’s Human Pregnane X Receptor reporter assay allows you to quickly screen test samples to quantify functional activity, either agonist or antagonist, they may exert against PXR (NR1I2). Kit includes cryopreserved reporter cells engineered to provide constitutive expression of the receptor, optimized media for use during cell thawing and in diluting test samples, reference agonist, Luciferase Detection Reagent, cell culture-ready assay plate, and detailed assay protocol. INDIGO’s unique Cryomite™ process provides exceptional cell viability post-thaw and INDIGO’s strict QA process means consistent results lot to lot (product quality data available upon request). This kit allows researchers to achieve superior sensitivity, clear, reproducible results, and eliminate weeks of cell culture work.
Echelon Biosciences Research Labs PI(4,5)P2 DiC4 500 ug
Phosphatidylinositol 4,5-bisphosphate diC4 (PI(4,5)P2 diC4) is a synthetic, purified dibutanoyl PI(4,5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K). This item is non returnable
Meso Scale Discovery R-PLEX Human Periostin/OSF-2 Assay, Singleplex, SECTOR plates, 5 plates, compatible with MESO SECTOR instruments, Research Use Only
The MESO SCALE DISCOVERY R-PLEX Human Periostin/OSF-2 Assay is a specialized immunoassay designed for the detection of human Periostin/OSF-2. Utilizing advanced electrochemiluminescence technology, this assay ensures high sensitivity and reliability for biomarker discovery and development. The complete kit includes all essential components for easy assay setup and execution, making it ideal for research applications.
- Designed for research use only
- Electrochemiluminescence assay principle
- Singleplex format for specific analyte detection
- Compatible with MESO SECTOR instruments
- Comes with biotinylated capture and SULFO-TAG™ detection antibodies
- Includes calibrator, diluents, and MSD GOLD™ Read Buffer B
- Lower limit of detection calculated at 2.5 standard deviations above background
- Supports multiplexing with other analytes using R-PLEX Assay Designer
- Quick and easy assay development process
Enzo Life Sciences GFP-CERTIFIED FLUOFORTE Calcium assay kit (10x96wells)
Enzo Life Sciences’ GFP-CERTIFIED FLUOFORTE Calcium Assay Kit (high-throughput) provides a homogeneous fluorescence-based assay for detecting intracellular calcium mobilization across a broad spectrum of biological targets. Relative to other commercially available dyes, the GFP-CERTIFIED FLUOFORTE dye is the brightest and most sensitive fluorescent calcium indicator. The kit provides a homogeneous mix-and-read, no-wash calcium mobilization assay. The homogenous cell-based assay for calcium offers fewer steps, lower variability and an easier protocol for adherent and non-adherent cell lines. In addition, it requires neither a washing step, nor exogenous addition of a quencher dye, which could adversely effect receptor-ligand interaction kinetics. Applications: Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS .
Enzo Life Sciences Blebbistatin(+/-), (5mg), CAS Number: 674289-55-5
Inhibitor of non-muscle myosin II. Blebbistatin (so named because of its ability to block cell blebbing) is a selective and high-affinity (IC50 approx. 4 µM) inhibitor of non-muscle myosin II. During cell division blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis. It inhibits pancreatic adenocarcinoma cellular invasiveness and PDGF-stimulated fibroblast-collagen matrix contraction. Formula: C18H16N2O2. MW: 292.3. CAS Number: 674289-55-5. Purity: ≥97%. Appearance: Bright yellow solid. Solubility: Soluble in DMSO (25mg/ml). Long Term Storage: -20°C