General Cell Based Assays
Eurofins Discoverx PathHunter eXpress TRHR Total Internalization Assay, 10pl Kit. (93-0949E3CP5L)
The PathHunter TRHR Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of TRHR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged TRHR and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the TRHR receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human GPR143 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR143 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR143 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TACR3 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human TACR3 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure TACR3 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress VIPR2 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0052E2CP2M)
The cAMP Hunter VIPR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. VIP) based activation of VIPR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type VIPR2, a naturally Gs coupled GPCR. Upon activation of VIPR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
National Diagnostics Diogenes Cellular Luminescence Enhancement System, Superoxide detection, Non-cytotoxic, Requires fewer cells, Assay Yield: Up to 100 assays per 10 ml
Diogenes Cellular Luminescence Enhancement System, Superoxide detection, Non-cytotoxic, Requires fewer cells, Assay Yield: Up to 100 assays per 10 ml
Electron Microscopy Sciences Flim Sleeve 135 mm/36 exp with Frosted Open Flap
Polyguard Polypropylene film sleeves are the finest archival quality material, and are guaranteed to give you ultimate protection for your most important film negatives. Polyguard is 100% acid free, as well as being free from optical distortion. It is resistant to water, grease, oil, alkalies, and organic solvents. Polyguard is durable, yet pliable and gentle to the film and will not become brittle, crack, or abrade the film.
Type: Frosted Open Flap
Eurofins Discoverx PathHunter eXpress PTGIR Total Internalization Assay, 2pl Kit. (93-0838E3CP0M)
The PathHunter PTGIR Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of PTGIR via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged PTGIR and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the PTGIR receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sciencell Research Laboratories Human Non-Pigmented Ciliary Epithelial Cells Kit
solated from human ciliary body. HNPCEpiC are cryopreserved at P0 and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume.Kit includes:Cells (Catalog #6580), Specialty Medium (Catalog #4101), DPBS (Catalog #0303), Trypsin/EDTA (Catalog #0183), Trypsin Neutralizing Solution (Catalog #0113), PLL (Catalog #0413)
BioVendor, LLC QuickZyme Sensitive Tissue Hydroxyproline Kit 96-Assays (for collagen analysis)
QuickZyme Sensitive Tissue Hydroxyproline Kit, 96-Assays. Measure hydroxyproline in small tissue samples with low collagen levels! The ONLY hydroxyproline-based assay which shows no matrix effect and no need for further dilution of the hydrolysate, enabling measurement in small samples with low hydroxyproline levels. No drying of hydrolysate is needed, resulting in a fast (<2 hrs), sensitive and easy (96-well plate format) assay. Dynamic range: 6-300 uM. Sensitivity: 0.3 ug/ml. Species independent. Measures total hydroxyproline. If this hydroxyproline is obtained upon hydrolysis of collagen, it represents all collagen types present without discriminating between types of collagen, procollagen, mature collagen and collagen degradation products. Hydroxyproline in tissue hydrolysates can be used as a direct measure of the amount of collagen present. Collagen hydrolysis tubes & protocol not included (if these items are needed, please order QuickZyme Sensitive Tissue Collagen Assay).
Eurofins Discoverx PathHunter eXpress mCMKLR1 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0537E2MCP0L)
The PathHunter mCMKLR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. chemerin) based activation of mCMKLR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCMKLR1 and EA-tagged β-Arrestin-2. Activation of mCMKLR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam RG 108, non-nucleoside DNA methyltransferase inhibitor (DNMT), 50MG
MW 334.3 Da, Purity >99%. Novel, non-nucleoside DNA methyltransferase (DNMT) inhibitor, capable of interacting with the DNMT1 active site (IC₅₀ = 115 nM). Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes in vitro. Capable of enhancing the efficiency of induced pluripotent stem cell (iPS) generation.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc ASPARTATE ASP COLORIMETRIC KIT
5000265389 ASPARTATE ASP COLORIMETRIC KIT
American Research Products Inc URIC ACID UA FLUOROMETRIC KIT
5000265018 URIC ACID UA FLUOROMETRIC KIT