General Cell Based Assays
Dojindo Molecular Technologies Inc Glucose Uptake Assay Kit-Green (1 set) , simple measurement of glucose uptake, 200 times more sensitive than 2-NBDG, no more radioactive waste, high cellular retention, Ex=507 nm, Em=518 nm.
Elevated glucose uptake is a marker of tumors, and glucose transporters are important targets in cancer treatment. One common method for evaluating the glucose uptake ability of cells uses radioisotope-labeled glucose. Although this method has been used for many years, it requires special handling facilities and disposal of radioactive materials, at the disadvantage of inconvenience and high cost. 2-NBDG has been used widely to detect cellular glucose uptake, but the sensitivity is poor because of the low fluorescence intensity.Glucose Uptake Probe-Green has resolved those limitations. This probe emits strong green fluorescence (Ex=507 nm, Em=518 nm), allowing for easy detection of glucose uptake over 200 times more sensitive than 2-NBDG by fluorescent microscope, microplate reader, and flow cytometry.The WI Solution in this kit enhances cellular retention of the probe to give more reliable data. Glucose Uptake Assay Kit-Green is qualified for screening purposes.
Abcam Heme Assay Kit
Heme Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Electron Microscopy Sciences Flim Sleeve 135 mm/36 exp with Clear open flap
Polyguard Polypropylene film sleeves are the finest archival quality material, and are guaranteed to give you ultimate protection for your most important film negatives. Polyguard is 100% acid free, as well as being free from optical distortion. It is resistant to water, grease, oil, alkalies, and organic solvents. Polyguard is durable, yet pliable and gentle to the film and will not become brittle, crack, or abrade the film.
Type: Clear open flap
Eurofins Discoverx PathHunter Panitumumab Bioassay Kit, 2-Plate. (93-1051Y3-00093)
The PathHunter Panitumumab Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses EGF-induced dimerization of ErbB2 and EGFR receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of ErbB2 and EGFR, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Panitumumab Bioassay Kit, 10-Plate. (93-1051Y3-00094)
The PathHunter Panitumumab Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses EGF-induced dimerization of ErbB2 and EGFR receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of ErbB2 and EGFR, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Apexbio Technology LLC DiscoveryProbe™ PI3K/Akt/mTOR Compound Library 100uL/well(10 mM solution),96 Well Deep Well Plate
The DiscoveryProbe PI3K/Akt/mTOR Compound Library comprises 178 small molecule inhibitors targeting PI3K/Akt/mTOR-related signaling pathways This pathway regulates processes such as cell growth proliferation survival apoptosis and metabolism in various cell types making it a frequent focus for oncology and disease mechanism research The collection encompasses compounds approved by regulatory agencies including FDA and EMA and agents studied extensively in academic and pharmaceutical research settings Representative inhibitors within this library include PI3K-selective inhibitors ATM/ATR inhibitors (DNA damage response regulators) and DNA-PK and GSK-3 targeting compounds providing comprehensive coverage for biological pathway elucidation drug discovery screening and pharmacological mechanism-of-action studies
Hycult Biotech Inc LAL CHROMOGENIC ENDPOINT ASSAY
The LAL assays is to be used for the in vitro quantitative determination of bacterial endotoxin in various biological fluids (including sera), devices, (air)filters and tissue culture medium.
ABclonal Technology Pyruvate carboxylase (PC) Rabbit mAb
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5 UTRs, but encoding the same protein, have been found for this gene.
Eurofins Discoverx PathHunter eXpress GPR50 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0648E2CP1M)
The PathHunter GPR50 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR50 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR50 and EA-tagged β-Arrestin-2. Activation of GPR50 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Tissue type Plasminogen Activator Activity Assay Kit (Colorimetric, Human)
Tissue type Plasminogen Activator Activity Assay Kit (Colorimetric, Human)
The product is subject to the following: Abcam Restricted Use Statement
Abcam MitoTox™ Complex II +¿III OXPHOS Activity¿Assay Kit
MitoTox™ Complex II +¿III OXPHOS Activity¿Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx cAMP Hunter eXpress CRHR1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0047E2CP2L)
The cAMP Hunter CRHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CRH, sauvagine) based activation of CRHR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CRHR1, a naturally Gs coupled GPCR. Upon activation of CRHR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Molecular Devices Neurotransmitter Uptake Assay, Explorer, Homogeneous, 96/384-Well
Molecular Devices' Neurotransmitter Transporter Uptake Assay Explorer Kit provides a homogeneous, fluorescence-based method to measure dopamine, norepinephrine, and serotonin transporter (DAT, NET, SERT) uptake activity in live cells. The no-wash format supports kinetic and endpoint reads and is optimized for high-throughput screening and for use with transfected or endogenously expressing cells.
- Homogeneous no-wash assay format.
- Fluorescent substrate for DAT, NET, and SERT uptake.
- Five lyophilized reagent vials, each sufficient for one 96- or 384-well plate.
- Compatible with bottom-read fluorescence microplate readers and kinetic read modes.
- Store reagents at -20°C; dye solution stable up to eight hours at room temperature or up to five days when aliquoted and frozen.
Molecular Devices Fluorescent Assay Kit, cAMP, 96-Well, Bulk
The CatchPoint cAMP Fluorescent Assay Kit is a 96-well competitive immunoassay for quantitative measurement of intracellular or biochemical cAMP levels in cell-based and enzymatic assays. It provides high-affinity reagents and pre-coated microplates optimized for sensitive fluorescence detection.
- Format: 96-well bulk kit with reagents for ten 96-well plates.
- Target analyte: 3',5'-cyclic adenosine monophosphate (cAMP).
- Detection: fluorescent competitive immunoassay, 120 μL total assay volume per well.
- Contents: pre-coated black 96-well plates, rabbit anti-cAMP antibody, HRP-cAMP conjugate, cAMP calibrator, substrate, assay buffer, wash concentrate, cell lysis buffer.
- Incubation: 2 hours for antibody/conjugate incubation; substrate signal readable from 10 minutes up to 24 hours.
- Storage: store components at 4°C; reconstituted reagents stable for about 3 weeks at 4°C.