General Cell Based Assays
Eurofins Discoverx PathHunter C5AR1 Bioassay Kit, 2-Plate. (93-0557Y2-00059)
The PathHunter C5AR1 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. C5a) based activation of C5AR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged C5AR1 and EA-tagged β-Arrestin-2. Activation of C5AR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress mOPRM1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0524E3MCP5M)
The PathHunter mOPRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE) based activation of mOPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRM1 and EA-tagged β-Arrestin-2. Activation of mOPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCCR3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0522E2MCP0L)
The PathHunter mCCR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL24) based activation of mCCR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR3 and EA-tagged β-Arrestin-2. Activation of mCCR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mOPRM1 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0524E3MCP5L)
The PathHunter mOPRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE) based activation of mOPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRM1 and EA-tagged β-Arrestin-2. Activation of mOPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rPROKR1 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0544PE2RCP0L)
The PathHunter rPROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokineticin) based activation of rPROKR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rPROKR1 and EA-tagged β-Arrestin-2. Activation of rPROKR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCCR7 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0528PE2MCP0M)
The PathHunter mCCR7 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL19/MIP-3β) based activation of mCCR7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR7 and EA-tagged β-Arrestin-2. Activation of mCCR7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rPROKR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0544PE2RCP0M)
The PathHunter rPROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokineticin) based activation of rPROKR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rPROKR1 and EA-tagged β-Arrestin-2. Activation of rPROKR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCCR2 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0543E3MCP5M)
The PathHunter mCCR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL2/MCP-1) based activation of mCCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR2 and EA-tagged β-Arrestin-2. Activation of mCCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress LGR5 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0526E2ACP1M)
The PathHunter LGR5 (GPR49) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. R-spondins) based activation of LGR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged LGR5 and EA-tagged β-Arrestin-2. Activation of LGR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCCR4 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0515E2MCP0M)
The PathHunter mCCR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL22/MDC) based activation of mCCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR4 and EA-tagged β-Arrestin-2. Activation of mCCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
MilliporeSigma™ InnoCyte™ ECM Cell Adhesion Assay, Fibronectin
ECM cell adhesion to fibronectin
R&D Systems™ Mouse CD8+ T Cell Enrichment Column, Small
Designed to prepare sub-populations of CD8 mouse T cells via high affinity negative selection
MilliporeSigma™ LC3-II Enrichment Kit (Western Blot)
Enables sensitive and accurate quantification of autophagosome density by utilizing selective permeabilization procedure that removes cytosolic LC3-I and retains autophagosome-bound LC3-II
MilliporeSigma™ Muse™ RBC Invasion Assay
The Muse™ RBC Invasion kit is a parasitemia assays for determination of extent of RBC infection.
MilliporeSigma™ AXIS™ Axon Isolation Device, 450μm
For Cell Culture